14 Results for "

Siegesbeckia

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "Siegesbeckia" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N6028
CAS No.: 59219-65-7
Darutoside is an orally effective diterpene compound with significant anti-inflammatory, analgesic, wound healing promotion, and immunomodulatory activities. Darutoside reduces edema and pain responses by inhibiting the expression of COX-2 and the migration of inflammatory cells. It regulates macrophage polarization towards the M2 type by inhibiting the NF-κB pathway, alleviating inflammation and promoting wound healing. Through multi-target regulation of metabolic networks, Darutoside significantly alleviates acute gouty arthritis .
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Cat. No.: HY-N1496
CAS No.: 1188282-02-1
Target:  

Others

Research Areas:  

Others

15,16-Di-O-acetyldarutoside (compound 5) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
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Cat. No.: HY-N4245
CAS No.: 196399-16-3
Siegesmethyletheric acid is isolated from the ethyl acetate fraction of Siegesbeckia orientalis L. (Asteraceae) .
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Cat. No.: HY-N11547
CAS No.: 145042-08-6
Leocarpinolide F is a natural sesquiterpenoid that can be isolated from Siegesbeckia orientalis .
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Cat. No.: HY-N3972
CAS No.: 22338-69-8
Grandifloric acid is a Diterpenoids product that can be isolated from the herbs of Siegesbeckia orientalis L. .
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Cat. No.: HY-N6028R
CAS No.: 59219-65-7
Darutoside (Standard) is the analytical standard of Darutoside. This product is intended for research and analytical applications. Darutoside is a diterpenoid isolated from Siegesbeckia .
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Cat. No.: HY-N0559R
CAS No.: 52659-56-0
Kirenol (Standard) is the analytical standard of Kirenol (HY-N0559). This product is intended for research and analytical applications. Kirenol is a diterpenoid compound, an orally active apoptosis inducer and signaling pathway regulator, with a Kd value of 5.47 μM against the target CK2. Kirenol promotes the cleavage of Bid into tBid, regulates the protein levels/phosphorylation of Bax, Bcl-2, p53 and p21, and induces caspase-independent apoptosis, S-phase cell cycle arrest, ROS accumulation and cytotoxicity in cancer cells. Kirenol activates the CK2/AKT and AMPK-mTOR-ULK1 pathways, inhibits the signaling of NF-κB, TGF-β/Smads and NLRP3 inflammasome, and regulates the GSK3β, BMP and Wnt/β-catenin pathways. Kirenol induces autophagy, mitophagy and osteoblast differentiation, promotes mitochondrial fusion, and exerts antioxidant, anti-inflammatory, antifibrotic, renoprotective, cardioprotective, neuroprotective and analgesic effects. Kirenol is applicable to research related to chronic myeloid leukemia, ischemic stroke, diabetic nephropathy, heart failure, acute lung injury and osteoporosis.
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Cat. No.: HY-N3812
CAS No.: 1188281-98-2
ent-14,16-Epoxy-8-pimarene-3,15-diol is a Diterpenoids product that can be isolated from the herbs of Siegesbeckia orientalis .
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Cat. No.: HY-N3814
CAS No.: 3301-61-9
ent-16β,17-Dihydroxykauran-19-oic acid is an anti-inflammatory agent, which can be isolated from Siegesbeckia pubescens herb. ent-16β,17-Dihydroxykauran-19-oic acid inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia .
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Cat. No.: HY-N21533
CAS No.: 335150-90-8
Pubeside D is a kaurane-type diterpenoid glycoside that exists in Siegesbeckia glabrescens, Siegesbeckia orientalis and Siegesbeckia pubescens .
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Cat. No.: HY-N19943
CAS No.: 2095244-07-6
Siegeside B is a diterpenoid glycoside found in the dried aerial parts of Siegesbeckia pubescens. Siegeside B inhibits epidermal growth factor-induced migration and invasion of breast cancer cells. Siegeside B can be used for the research of breast cancer .
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Cat. No.: HY-N2751
CAS No.: 1188281-99-3
7-Hydroxydarutigenol is a Diterpenoids product that can be isolated from the herbs of Siegesbeckia orientalis .
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Cat. No.: HY-N1603
CAS No.: 1188282-01-0
Target:  

Others

Research Areas:  

Others

16-o-Acetyldarutigenol (compound 4) is an ent-pimarane diterpenoid compound isolated from the ethanol extract of Siegesbeckia orientalis .
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Cat. No.: HY-N0559A
CAS No.: 1622876-96-3
(6-Rac)-Kirenol is an ent-pimarane-type diterpenoid. (6-Rac)-Kirenol inhibits the production of superoxide anions in activated human neutrophils. (6-Rac)-Kirenol inhibits the release of elastase from activated human neutrophils .
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