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Cat. No.: HY-N0559A

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(6-Rac)-Kirenol

(6-Rac)-Kirenol is an ent-pimarane-type diterpenoid. (6-Rac)-Kirenol inhibits the production of superoxide anions in activated human neutrophils. (6-Rac)-Kirenol inhibits the release of elastase from activated human neutrophils.

For research use only. We do not sell to patients.

CAS No.: 1622876-96-3
Formula: C₂₀H₃₄O₄
Molecular Weight:338.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(6-Rac)-Kirenol Chemical Structure

CAS No.: 1622876-96-3

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
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Biological Activity

Description

In Vitro

(6-Rac)-Kirenol (compound 15) (10 μg/mL) inhibits superoxide anion generation in FMLP/CB-activated human neutrophils with 38.44% inhibition at 10 μg/mL and an IC₅₀ > 10 μg/mL^[1].
(6-Rac)-Kirenol (10 μg/mL) inhibits elastase release in FMLP/CB-activated human neutrophils with 21.80% inhibition at 10 μg/mL and an IC₅₀ > 10 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1622876-96-3
Molecular Weight 338.49
Formula C₂₀H₃₄O₄
SMILES

C[C@]12[C@]3(C(=C[C@](C(CO)O)(C)CC3)CC[C@@]1([C@@](CO)(C)C[C@@H](O)C2)[H])[H]
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang R, et al. In vitro anti-inflammatory effects of diterpenoids and sesquiterpenoids from traditional Chinese medicine Siegesbeckia pubescens. Bioorganic & medicinal chemistry letters. 2014 Aug 15;24(16):3944-7. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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