Tephrosia candida DC.

Darutoside is an orally effective diterpene compound with significant anti-inflammatory, analgesic, wound healing promotion, and immunomodulatory activities. Darutoside reduces edema and pain responses by inhibiting the expression of COX-2 and the migration of inflammatory cells. It regulates macrophage polarization towards the M2 type by inhibiting the NF-κB pathway, alleviating inflammation and promoting wound healing. Through multi-target regulation of metabolic networks, Darutoside significantly alleviates acute gouty arthritis.

ent-16β,17-Dihydroxykauran-19-oic acid is an anti-inflammatory agent, which can be isolated from Siegesbeckia pubescens herb. ent-16β,17-Dihydroxykauran-19-oic acid inhibits lipopolysaccharide-induced nitric oxide production in BV2 microglia.

Pubeside D is a kaurane-type diterpenoid glycoside that exists in Siegesbeckia glabrescens, Siegesbeckia orientalis and Siegesbeckia pubescens.

(6-Rac)-Kirenol is an ent-pimarane-type diterpenoid. (6-Rac)-Kirenol inhibits the production of superoxide anions in activated human neutrophils. (6-Rac)-Kirenol inhibits the release of elastase from activated human neutrophils.

Siegeside B is a diterpenoid glycoside found in the dried aerial parts of Siegesbeckia pubescens. Siegeside B inhibits epidermal growth factor-induced migration and invasion of breast cancer cells. Siegeside B can be used for the research of breast cancer.

Rotenonone is a derivative of Rotenone (HY-B1756), with a LD₅₀ of 0.68 μg/g against larvae of Spodoptera litura.

Psoracorylifol A is a Helicobacter pylori inhibitor present in the seeds of Psoralea corylifolia, with an MIC of 25 μg/mL against H. pylori strain SS1 and the metronidazole-resistant strain ATCC 43504. Psoracorylifol A is applicable to research related to Helicobacter pylori infection.

Ent-17α,18-dihydroxy-kauran-19-oic acid (81) is a natural compound that can be isolated from S. pubescens.

Siegeskaurolic acid is an orally active anti-inflammatory agent. Siegeskaurolic acid inhibits the productions of nitric oxide (NO), prostaglandin E(2) (PGE(2)), tumor necrosis factor-alpha (TNF-alpha) and the activationon of nuclear factor-kappaB .

Darutoside (Standard) is the analytical standard of Darutoside. This product is intended for research and analytical applications. Darutoside is a diterpenoid isolated from Siegesbeckia.