Rotenonone
Rotenonone is a derivative of Rotenone (HY-B1756), with a LD50 of 0.68 μg/g against larvae of Spodoptera litura.
For research use only. We do not sell to patients.
- CAS No.: 4439-62-7
- Formula: C23H18O7
- Molecular Weight:406.38
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Fourth-instar armyworm larvae (average body weight 4.95 g)[1]
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Dosage:0.8; 0.4; 0.2 and 0.08 μg/g body weight
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Administration:topical; single dose
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Result:Induced 55% mortality at 0.8 μg/g body weight at 120 hours post-treatment.
Induced 37% mortality at 0.4 μg/g body weight at 120 hours post-treatment.
Induced 20% mortality at 0.2 μg/g body weight at 120 hours post-treatment.
Induced 10% mortality at 0.08 μg/g body weight at 120 hours post-treatment.
Determined an LD50 of 0.68 μg/g body weight.
Chemical Information
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CAS No. 4439-62-7
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Molecular Weight 406.38
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Formula C23H18O7
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SMILES
O=C1C(C2=CC(OC)=C(OC)C=C2O3)=C(OC4=C(C[C@@H](O5)C(C)=C)C5=CC=C41)C3=O
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Acute Systemic Toxicity Study
Acute systemic toxicity studies evaluate adverse effects occurring after a single exposure, or repeated exposure within a short acute window, and the main in vivo readouts are mortality, moribund condition, clinical signs, body-weight change, and gross pathological findings; acute oral toxicity methods were developed to replace classical LD50 testing with reduced-animal designs such as fixed-dose procedure, acute toxic class method, and up-and-down procedure. The fixed-dose procedure classifies acute toxicity by administering predefined dose levels and observing evident toxicity rather than using death as the primary endpoint, whereas the acute toxic class method uses sequential groups of three animals per step and the up-and-down procedure doses animals sequentially to estimate an LD50 with fewer animals than conventional LD50 testing.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Rotenonone Related Classifications
HY-N11731 Related Classifications
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