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Cat. No.: HY-N19943

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Siegeside B

Siegeside B is a diterpenoid glycoside found in the dried aerial parts of Siegesbeckia pubescens. Siegeside B inhibits epidermal growth factor-induced migration and invasion of breast cancer cells. Siegeside B can be used for the research of breast cancer.

For research use only. We do not sell to patients.

CAS No.: 2095244-07-6
Formula: C₂₆H₄₄O₈
Molecular Weight:484.62

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Siegeside B Chemical Structure

CAS No.: 2095244-07-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
MDA-MB-231	IC₅₀	0.27 μM Compound: 2	Inhibition of EGF-induced invasion of human MDA-MB-231 cells by MTT assay Inhibition of EGF-induced invasion of human MDA-MB-231 cells by MTT assay	[PMID: 28302401]

In Vitro

Siegeside B potently inhibits EGF-induced invasion of MB-MDA-231 breast cancer cells with an IC₅₀ of 0.27 µM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2095244-07-6
Molecular Weight 484.62
Formula C₂₆H₄₄O₈
SMILES

C[C@]12[C@@]3([H])C(CC[C@]1([H])C(C)([C@@H](CC2)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO)C)=C[C@](C)(CC3)[C@H](O)CO
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Wang J, et al. Isolation and characterization of diterpene glycosides from Siegesbeckia pubescens. Bioorg Med Chem Lett. 2017;27(8):1815-1819. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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