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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
TAOK1 kinase
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "TAOK1 kinase" in MCE Product Catalog:
6
TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death .
Cat. No.: HY-181280
Target:
Research Areas:
VU6083859 is a blood-brain barrier-permeable TAOK1 inhibitor with an IC50 of 158 nM. VU6083859 selectively inhibits TAOK1, exhibits only weak or no activity against TAOK2 and TAOK3, and shows high selectivity for a variety of other kinases. VU6083859 is applicable to research related to neurodevelopmental disorders and tauopathies.
Cat. No.: HY-P702749
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: TAOK1; Serine/Threonine-Protein kinase TAO1; TAO kinase 1; Prostate-Derived STE20-Like kinase 2; MAP3K16; kinase From Chicken Homolog B; HTAOK1; FLJ14314; HKFC-B; PSK-2; MARKK; Microtubule Affinity Regulating kinase kinase; PSK2; Serine/Threonine Protein
Species:
Human
Source:
Sf9 insect cells
Cat. No.: HY-181619
CAS No.: 3114565-22-6
Target:
Research Areas:
TAO Kinase-IN-3 is a potent pan-TAOK (Thousand-And-One Kinase) inhibitor that specifically binds to and inhibits the kinase activities of TAOK1, TAOK2 and TAOK3 with Kd values of <0.17 nM, 0.34 nM, and 0.17 nM, respectively. TAO Kinase-IN-3 can be used to study Alzheimer's disease, primary tauopathies and related syndromes. In addition, TAO Kinase-IN-3 is also widely used in research on the mechanisms of cancer cachexia and the muscle atrophy it induces .
Cat. No.: HY-181281
Target:
Research Areas:
VU6080195 is a blood-brain barrier-permeable pan-TAOK activator. VU6080195 shows the highest potency against TAOK1 (EC50 = 270 nM), followed by TAOK3 (EC50 = 503 nM) and TAOK2 (EC50 = 1,376 nM). VU6080195 can be used for the research of diseases such as neurodevelopmental disorders, tauopathies and breast cancer .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
