850467-66-2
Chemical Structure
TAO Kinase inhibitor 1
Synonym(s): CP 43
- CAS. Nr.: 850467-66-2
- Formula:C25H24N2O2
- Molecular Weight:384.47
IUPAC Name: N-(2-oxo-2-((1,2,3,4-tetrahydronaphthalen-1-yl)amino)ethyl)-[1,1'-biphenyl]-4-carboxamide
InChIKey: WQKXOAJVNFOHNZ-UHFFFAOYSA-N
SMILES: O=C(CNC(C1=CC=C(C2=CC=CC=C2)C=C1)=O)NC(CCC3)C4=C3C=CC=C4
Biological Activity: TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death[1].
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TAO Kinase inhibitor 1 | 99.81% | TAO Kinase inhibitor 1 (compound 43) is a selective, ATP-competitive thousand-and-one amino acid kinases (TAOK) inhibitor with IC50s of 11 to 15 nM for TAOK1 and 2, respectively. TAO Kinase inhibitor 1 delays mitosis and induces mitotic cell death. | ||||||||||||||||||||
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Keywords