2 Results for "

TNF/IFN-γ-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "TNF/IFN-γ-IN-1" in MCE Product Catalog:

Cat. No.: HY-161016
CAS No.: 876013-29-5
Target:  

TNF Receptor IFNAR

Research Areas:  

Neurological Disease

TNF/IFN-γ-IN-1 (compound TGA) is a dual inhibitor of TNF and IFN-γ. TNF/IFN-γ-IN-1 can used in study Alzheimer’s disease .
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16
16 Cited Publications
Cat. No.: HY-19744
CAS No.: 2437475-16-4
Target:  

MyD88

Research Areas:  

Inflammation/Immunology

T6167923 is a selective inhibitor of MyD88-dependent signaling pathways. T6167923 directly binds to Toll/IL1 receptor (TIR) domain of MyD88 and disrupts MyD88 homodimeric formation. T6167923 inhibits NF-κB driven Staphylococcus enterotoxin AP (SEAP) activity, and improves anti-inflammatory activity with IC50s of 2.7 μM, 2.9 μM, 2.66 μM and 2.66 μM for IFN-γ, IL-1β, IL-6 and TNF-α, respectively .
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