2 Results for "

Tedisamil dihydrochloride

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Tedisamil dihydrochloride" in MCE Product Catalog:

Art. -Nr.: HY-126704A
CAS. Nr.: 132523-84-3
Synonyms: KC-8857 dihydrochloride
Target:  

Potassium Channel

Forschungsgebiete:  

Cardiovascular Disease

Tedisamil (KC-8857) dihydrochloride is an antiarrhythmic compound with important biological activities. Tedisamil dihydrochloride exhibits a significant slowing effect on heart rate, which is achieved by inhibiting the transient outward potassium current (I(to)) in the atrium. Tedisamil dihydrochloride inhibits multiple potassium currents, including IK, K(ATP), and PKA-activated chloride channels, thereby prolonging the cardiac action potential and QT interval, and increasing cardiac reentry. Tedisamil dihydrochloride has antiarrhythmic effects on ventricular arrhythmias and atrial flutter in animal models .
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Art. -Nr.: HY-126704
CAS. Nr.: 90961-53-8
Synonyms: KC-8857
Target:  

Potassium Channel

Forschungsgebiete:  

Cardiovascular Disease

Tedisamil (KC-8857) is an antiarrhythmic compound with important biological activities. Tedisamil exhibits a significant slowing effect on heart rate, which is achieved by inhibiting the transient outward potassium current (I(to)) in the atrium. Tedisamil inhibits multiple potassium currents, including IK, K(ATP), and PKA-activated chloride channels, thereby prolonging the cardiac action potential and QT interval, and increasing cardiac reentry. Tedisamil has antiarrhythmic effects on ventricular arrhythmias and atrial flutter in animal models .
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