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1 Result for "
Thalidomide-1-Me,4-OH
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "Thalidomide-1-Me,4-OH" in MCE Product Catalog:
Cat. No.: HY-W441376
CAS No.: 2244568-06-5
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Thalidomide-1-Me,4-OH is a Thalidomide (HY-14658) analogue. Thalidomide-1-Me,4-OH contains an extra methyl group on the glutarimide moiety of thalidomide, which is known to abrogate its ability to bind the E3 ligase CRBN. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
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