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Thalidomide-1-Me,4-OH

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Thalidomide-1-Me,4-OH is a Thalidomide (HY-14658) analogue. Thalidomide-1-Me,4-OH contains an extra methyl group on the glutarimide moiety of thalidomide, which is known to abrogate its ability to bind the E3 ligase CRBN. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.

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  • Purity: 98.0%
  • CAS No.: 2244568-06-5
  • Formula: C14H12N2O5
  • Molecular Weight:288.26
  • Storage:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • Thalidomide-1-Me,4-OH Chemical Structure
    Thalidomide-1-Me,4-OH Chemical Structure
CAS No.: 2244568-06-5
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  • Thalidomide-1-Me,4-OH Chemical Structure
    Thalidomide-1-Me,4-OH Chemical Structure
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  • Thalidomide-1-Me,4-OH