Search Result
Results for "
Trisodium
" in MedChemExpress (MCE) Product Catalog:
36
Biochemical Assay Reagents
8
Isotope-Labeled Compounds
| Cat. No. |
Product Name |
Target |
Research Areas |
Chemical Structure |
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- HY-113596
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Acetyl-CoA Trisodium
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Oxidative Phosphorylation
Endogenous Metabolite
Autophagy
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Metabolic Disease
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Acetyl-coenzyme A (Acetyl-CoA) trisodium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trisodium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trisodium is also a key precursor of lipid synthesis .
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- HY-107837
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2-Phospho-L-ascorbic acid Trisodium
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Phosphatase
Reactive Oxygen Species (ROS)
Endogenous Metabolite
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Metabolic Disease
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L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression . L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation .
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- HY-B2201
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- HY-N7033
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Uridine 5'-diphosphoglucuronic acid Trisodium salt
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Drug Intermediate
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Metabolic Disease
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UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
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- HY-W013093
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- HY-W009362
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Endogenous Metabolite
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Cardiovascular Disease
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DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is an intermediate product in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products .
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- HY-12695
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5'-GTP Trisodium
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Exosomes
Endogenous Metabolite
DNA/RNA Synthesis
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Metabolic Disease
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate trisodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
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- HY-B1610
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Trisodium citrate dihydrate; Citric acid Trisodium salt dihydrate
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Environmental Pollutants
Endogenous Metabolite
Apoptosis
Bacterial
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Infection
Cardiovascular Disease
Cancer
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Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .
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- HY-W011184
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Endogenous Metabolite
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Metabolic Disease
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6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite .
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- HY-106950A
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Diphosphofructose Trisodium; Esafosfan Trisodium; FDP Trisodium
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Endogenous Metabolite
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Cardiovascular Disease
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Fosfructose trisodium (Diphosphofructose trisodium, Esafosfan trisodium, FDP trisodium) is a cytoprotective natural sugar phosphate used in research on cardiovascular ischemia, sickle cell anemia, and asthma. Fosfructose trisodium acts by stimulating anaerobic glycolysis, which produces adenosine triphosphate under ischemic conditions .
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- HY-126303C
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GS-441524 triphosphate Trisodium; Remdesivir metabolite Trisodium
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DNA/RNA Synthesis
SARS-CoV
RSV
HCV
Drug Metabolite
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Infection
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GS-443902 trisodium (GS-441524 triphosphate trisodium) is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor with IC50s of 1.1 μM, 5 μM for RSV RdRp and HCV RdRp, respectively. GS-443902 trisodium is the active triphosphate metabolite of Remdesivir (GS-5734) .
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- HY-12688A
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Mitochondrial Metabolism
Reactive Oxygen Species (ROS)
Amyloid-β
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Neurological Disease
Inflammation/Immunology
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Succinyl phosphonate trisodium salt is a α-Ketoglutarate Dehydrogenase Complex (KGDHC) modulator with neuroprotective activity. Succinyl phosphonate trisodium salt protects this complex, reduces cellular succinyl-CoA concentration, downregulates protein succinylation levels, and inhibits the activity of the α-ketoglutarate dehydrogenase complex. Succinyl phosphonate trisodium salt corrects hypoxic or ethanol-induced behavioral impairments, modulates exploratory behavior and emotional stress responses, and improves hypoxia tolerance. Succinyl phosphonate trisodium salt reduces glutamate excitotoxicity, restores the activity of the α-ketoglutarate dehydrogenase complex, reverses the changes in glutamate dehydrogenase and glutamine synthetase activities induced by β-amyloid (Amyloid-β), modulates cognitive function, and prevents β-amyloid-induced neuronal damage. Succinyl phosphonate trisodium salt improves microglial senescence, alleviates neuroinflammation, reactive oxygen species (ROS) production, lipid peroxidation, and the expression of proinflammatory cytokines. Succinyl phosphonate trisodium salt can be used in the research of Alzheimer's disease, aging-related neuroinflammation, and Parkinson's disease .
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- HY-B1318
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Trisodium phosphonoformate; Phosphonoformic acid Trisodium salt
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DNA/RNA Synthesis
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Infection
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Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis .
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- HY-17026E
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dFdCTP Trisodium
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Drug Metabolite
DNA/RNA Synthesis
Apoptosis
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Cancer
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Gemcitabine triphosphate (dFdCTP) trisodium is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate trisodium cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate trisodium shows a Ki of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate trisodium partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate trisodium disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate trisodium can be used for the research of pancreatic cancer and non-small cell lung cancer .
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- HY-103265
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FPL 67156 Trisodium
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NTPDase
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Cardiovascular Disease
Inflammation/Immunology
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ARL67156 (FPL 67156) trisodium is a selective small molecular inhibitor, targeting to ecto-ATPase, CD39, and CD73. ARL67156 trisodium is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12?μM, respectively. ARL67156 trisodium can be used in the research of calcific aortic valve disease, asthma .
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- HY-B1610E
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- HY-B1009
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EDTA Trisodium salt; Trisodium EDTA
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Environmental Pollutants
Bacterial
SOD
Ferroptosis
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Cardiovascular Disease
Neurological Disease
Cancer
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Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
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- HY-100767
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Guanosine 5'-[β,γ-imido]triphosphate Trisodium
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Adenylate Cyclase
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Endocrinology
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Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .
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- HY-108648
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2-Methylthioadenosine diphosphate Trisodium; 2-Methylthio-ADP Trisodium
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P2Y Receptor
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Neurological Disease
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2-Methylthioadenosine diphosphate trisodium is a potent purinergic P2Y receptors agonist, with EC50s of 19, 6.2, and 5 nM for human P2Y13, mouse P2Y13 and human P2Y12, respectively. 2-Methylthioadenosine diphosphate trisodium has pEC50s of 8.29 and 5.75 for human P2Y1 and rat P2Y6, respectively. 2-Methylthioadenosine diphosphate trisodium induces platelet aggregation and shape change, and inhibits cyclic AMP accumulation in platelets exposed to prostaglandin E1 .
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- HY-W587427
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Endogenous Metabolite
Monocarboxylate Transporter
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Neurological Disease
Cancer
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D-2-Phosphoglyceric acid trisodium is a glycolysis and gluconeogenesis intermediate with altered levels linked to MCT4-modulated glycolytic pathways. D-2-Phosphoglyceric acid trisodium shows reduced intracellular levels in hypoxic glioblastoma stem cells after MCT4 knockdown. D-2-Phosphoglyceric acid trisodium can be used for the research of glioblastoma .
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- HY-137888A
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oATP Trisodium salt
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P2X Receptor
NOD-like Receptor (NLR)
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Inflammation/Immunology
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Oxidized ATP (oATP) trisodium salt is a broad-spectrum P2 receptor inhibitor. Oxidized ATP trisodium salt irreversibly antagonizes P2X7R activation. Oxidized ATP trisodium salt inhibits c-reactive protein (CRP)-induced NLRP3 inflammasome activation. Oxidized ATP trisodium salt can be used for research of atherosclerosis .
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- HY-137683A
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GDPβS Trisodium
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Adenylate Cyclase
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Cardiovascular Disease
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Guanosine 5'-O-(2-thiodiphosphate) trisodium (GDPβS trisodium) is a non-hydrolyzable derivative of GDP. Guanosine 5'-O-(2-thiodiphosphate) trisodium acts as an inhibitor of adenylyl cyclase (AC) with a Ki value of 600 nM. In the absence of glutamic-pyruvic transaminase (GPT) in cerebral cortex membranes of rodent models, Guanosine 5'-O-(2-thiodiphosphate) trisodium partially activates AC with an EC50 of 400 nM. Guanosine 5'-O-(2-thiodiphosphate) trisodium prevents norepinephrine-induced nitric oxide release in ventricular myocytes .
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- HY-101400A
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dCTP Trisodium solution (100 mM); 2′-Deoxycytidine-5′-triphosphate Trisodium solution (100 mM)
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
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Metabolic Disease
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Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100 mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .
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- HY-W088066
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Bacterial
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Infection
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Trisodium phosphate dodecahydrate is an Antibacterial agent. Trisodium phosphate dodecahydrate reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate is used in poultry processing .
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- HY-W008661
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dGTP Trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate Trisodium solution (100 mM)
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DNA/RNA Synthesis
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Others
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Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
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- HY-107372A
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UTP Trisodium dihydrate; Uridine 5'-triphosphate Trisodium dihydrate
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Biochemical Assay Reagents
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Others
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Uridine triphosphate (trisodium dihydrate) (UTP (trisodium dihydrate); Uridine 5'-triphosphate (trisodium dihydrate)) is a biochemical reagent.
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- HY-W013256
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Trisodium phosphonoformate hexahydrate; Phosphonoformic acid Trisodium salt hexahydrate
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DNA/RNA Synthesis
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Infection
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Foscarnet trisodium hexahydrate (Trisodium phosphonatoformate hexahydrate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet trisodium hexahydrate is an antiherpesvirus agent used in cytomegalovirus retinitis .
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- HY-131521
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Oxalomalate Trisodium
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Isocitrate Dehydrogenase (IDH)
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Cancer
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Oxalomalic acid (Oxalomalate) trisodium is a aconitase and NADP-dependent isocitrate dehydrogenase inhibitor. Oxalomalic acid trisodium inhibits nitrite production and iNOS protein expression in lipopolysaccharide (HY-D1056)-activated J774 macrophages .
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- HY-N8060A
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Orotidine monophosphate Trisodium; Orotidylic acid Trisodium
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Endogenous Metabolite
DNA/RNA Synthesis
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Metabolic Disease
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Orotidine 5'-monophosphate trisodium is a pyrimidine nucleotide. Orotidine 5'-monophosphate trisodium is synthesized via the de novo synthesis pathway for DNA synthesis in a large number of microorganisms including M. tuberculosis, S. cerevisiae, S. typhimurium and P. falciparum to name a few. The synthesis of orotidine 5'-monophosphate trisodium uses phosphoribosyl pyrophosphate (PRPP) and orotic acid (OA) as the substrates catalyzed by orotate phosphoribosyltransferase (OPRT) .
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- HY-B0993
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MnDPDP
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Apoptosis
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Neurological Disease
Cancer
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Mangafodipir trisodium (MnDPDP), hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir trisodium shows no negative interference with the tumoricidal activity of chemotherapy .
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- HY-147338A
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5-Methyl-CTP Trisodium
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DNA/RNA Synthesis
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Others
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5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5′-triphosphate trisodium can apply in replacing unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells .
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- HY-135780A
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- HY-136650A
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F-ara-ATP Trisodium
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Nucleoside Antimetabolite/Analog
Drug Metabolite
DNA/RNA Synthesis
Apoptosis
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Cancer
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Fludarabine triphosphate (F-ara-ATP) trisodium, the active metabolite of Fludarabine (HY-B0069), is a potent, noncompetitive and specific inhibitor of DNA primase, with an IC50 of 2.3 μM and a Ki of 6.1 μM. Fludarabine triphosphate trisodium inhibits DNA synthesis by blocking DNA primase and primer RNA formation. Fludarabine triphosphate trisodium inhibits ribonucleotide reductase and DNA polymerase and ultimately leads to cellular apoptosis .
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- HY-Y1329
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- HY-103265B
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FPL 67156 Trisodium hydrate
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NTPDase
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Cardiovascular Disease
Inflammation/Immunology
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ARL67156 (FPL 67156) trisodium hydrate is a selective small is a selective samll molecular inhibitor, targeting to ecto-ATPase, CD39, and CD73. ARL67156 trisodium hydrate is also a competitive inhibitor of NTPDase1 (CD39), NTPDase3 and NPP1, with Kis of 11, 18 and 12 μM, respectively. ARL67156 trisodium hydrate can be used in the research of disease like calcific aortic valve disease, asthma .
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- HY-W010861
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- HY-136648B
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dATP Trisodium,100 mM Solution,PCR Grade
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Biochemical Assay Reagents
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Others
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2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade (dATP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. 2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade is used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
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- HY-W017068B
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2'-Deoxyuridine-5'-triphosphate Trisodium,100 mM Solution,PCR Grade
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Biochemical Assay Reagents
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Others
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dUTP trisodium,100 mM Solution,PCR Grade (2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade) is a highly stable nucleotide that can participate in the biosynthesis of DNA and is suitable for various conventional molecular biology experiments. This product is provided in the form of aqueous solution .
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- HY-112581B
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5-Methoxy-UTP Trisodium solution (100 mM); 5-OMe-UTP Trisodium solution (100 mM)
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DNA/RNA Synthesis
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Others
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5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase .
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- HY-B1610I
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Trisodium citrate dihydrate, for molecular biology
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Biochemical Assay Reagents
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Others
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Sodium citrate dihydrate, for molecular biology is an antacid used in studies to neutralize gastric acid. Sodium citrate dehydrate is often used to prepare biological buffers and can be used in molecular biology research .
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- HY-136648AR
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dATP Trisodium (Standard)
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Reference Standards
Endogenous Metabolite
DNA/RNA Synthesis
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Metabolic Disease
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2'-Deoxyadenosine-5'-triphosphate trisodium (Standard) (dATP trisodium (Standard)) is the analytical standard of 2'-Deoxyadenosine-5'-triphosphate trisodium (HY-136648A). This product is intended for research and analytical applications. 2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase .
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- HY-123979A
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NSC37044 Trisodium
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PKC
Apoptosis
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Cancer
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ζ-Stat trisodium (NSC37044 trisodium) is a specific and atypical PKC-ζ inhibitor, with an IC50 of 5 μM. ζ-Stat trisodium can reduce melanoma cell lines proliferation and induce apoptosis, and has antitumor activity in vitro .
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- HY-W854659
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Ce6 Trisodium
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Photosensitizer
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Cancer
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Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions .
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- HY-W008661A
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dGTP Trisodium,100 mM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate Trisodium,100 mM Solution,PCR Grade
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DNA/RNA Synthesis
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Others
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Deoxyguanosine triphosphate (dGTP) trisodium,100 mM Solution,PCR Grade is one of the raw materials used by DNA polymerases to synthesize long DNA strands during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
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- HY-115736A
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- HY-164094A
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- HY-134320B
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8-Azidoadenosine 5'-triphosphate Trisodium; 8-N3-ATP Trisodium
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Potassium Channel
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Metabolic Disease
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8-Azido-ATP (8-N3-ATP) trisodium, a photoreactable nucleotide analog, is useful for the identification of proteins, such as DNA-dependent RNA polymerase. 8-Azido-ATP trisodium is a click chemistry reagent that contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. 8-Azido-ATP trisodium can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups .
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- HY-W013256R
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Trisodium phosphonoformate hexahydrate (Standard); Phosphonoformic acid Trisodium salt hexahydrate (Standard)
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Reference Standards
DNA/RNA Synthesis
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Infection
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Foscarnet (trisodium hexahydrate) (Standard) is the analytical standard of Foscarnet (trisodium hexahydrate). This product is intended for research and analytical applications. Foscarnet trisodium hexahydrate (Trisodium phosphonatoformate hexahydrate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet trisodium hexahydrate is an antiherpesvirus agent used in cytomegalovirus retinitis .
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- HY-113371A
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Methylcitric acid Trisodium
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Endogenous Metabolite
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Metabolic Disease
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2-Methylcitric acid trisodium (Methylcitric acid trisodium) is an endogenous metabolite in the 2-methylcitric acid cycle. 2-Methylcitric acid trisodium accumulates in methylmalonic and propionic acidemias and acts as a marker metabolite. 2-Methylcitric acid trisodium markedly inhibits ADP-stimulated and uncoupled respiration in mitochondria supported by glutamate .
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- HY-109560
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Zn-DTPA Trisodium
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Biochemical Assay Reagents
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Others
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Pentetate zinc trisodium (Zn-DTPA trisodium) forms stable chelates with metal ions by exchanging zinc for a metal of greater binding capacity .
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- HY-N7033R
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Uridine 5'-diphosphoglucuronic acid Trisodium salt (Standard)
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Reference Standards
Drug Intermediate
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Metabolic Disease
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UDP-glucuronic acid (trisodium) (Standard) is the analytical standard of UDP-glucuronic acid (trisodium). This product is intended for research and analytical applications. UDP-?glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, ranging from mammalian glycosaminoglycans and plant cell wall polysaccharides to bacterial capsule glycoglycerolipids.
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- HY-W009362R
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Reference Standards
Endogenous Metabolite
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Others
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DL-Isocitric acid (trisodium salt) (Standard) is the analytical standard of DL-Isocitric acid (trisodium salt). This product is intended for research and analytical applications. DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is an intermediate product in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products.
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- HY-W011184R
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Reference Standards
Endogenous Metabolite
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Metabolic Disease
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6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.
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- HY-164840A
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DNA/RNA Synthesis
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Cancer
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Clofarabine-5'-triphosphate trisodium is the trisodium salt form of Clofarabine-5'-triphosphate (HY-164840). Clofarabine-5'-triphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-triphosphate trisodium exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .
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- HY-W013093R
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UTP Trisodium salt (Standard); Uridine 5'-triphosphate Trisodium salt (Standard)
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Reference Standards
Endogenous Metabolite
P2Y Receptor
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Cardiovascular Disease
Inflammation/Immunology
Cancer
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Uridine triphosphate (trisodium salt) (Standard) is the analytical standard of Uridine triphosphate (trisodium salt). This product is intended for research and analytical applications. Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors .
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- HY-W088066A
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Bacterial
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Infection
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Trisodium phosphate dodecahydrate, 98% is an Antibacterial agent. Trisodium phosphate dodecahydrate, 98% reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate, 98% modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate, 98% is used in poultry processing .
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- HY-W010771A
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dCTP Trisodium,100 mM Solution,PCR Grade; 2′-Deoxycytidine-5′-triphosphate Trisodium,100 mM Solution,PCR Grade
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DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Others
|
|
Deoxycytidine triphosphate (dCTP; 2′-Deoxycytidine-5′-triphosphate) trisodium,100 mM Solution,PCR Grade is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. This product is supplied as an aqueous solution .
|
-
- HY-W145618
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Trisodium Glycyrrhizinate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-B1009R
-
|
EDTA Trisodium salt (Standard); Trisodium EDTA (Standard)
|
Ferroptosis
Bacterial
SOD
Reference Standards
|
Cardiovascular Disease
Neurological Disease
Cancer
|
|
Ethylenediaminetetraacetic acid (trisodium salt) (Standard) is the analytical standard of Ethylenediaminetetraacetic acid (trisodium salt). This product is intended for research and analytical applications. Ethylenediaminetetraacetic acid trisodium salt (EDTA trisodium salt; Trisodium EDTA) is a kind of metal chelating agent (binds to bivalent and trivalent metal cations, including calcium). Ethylenediaminetetraacetic acid trisodium salt has antibacterial, anti-inflammatory, antioxidant, anti-hypercalcemia and anticoagulant activities. Ethylenediaminetetraacetic acid trisodium salt decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid trisodium salt can alleviate the liver fibrosis. Ethylenediaminetetraacetic acid can be used for coronary artery disease and neural system disease research .
|
-
- HY-W127847
-
|
Triglycollamic acid Trisodium salt
|
Environmental Pollutants
Biochemical Assay Reagents
|
Others
|
|
Nitrilotriacetic acid (Triglycollamic acid) trisodium salt is a chelating agent commonly used in various industrial processes, especially in the production of detergents, cleaners and metal plating solutions. Nitrilotriacetic acid trisodium salt has unique chemical properties that bind to metal ions, preventing them from reacting or precipitating out of solution.
|
-
- HY-137608A
-
|
UDP-β-S Trisodium
|
P2Y Receptor
DNA/RNA Synthesis
|
Cardiovascular Disease
Inflammation/Immunology
|
|
Uridine 5'-O-thiodiphosphate trisodium (UDP-β-S trisodium) is a P2Y6 receptor agonist with an EC50 of 25 nM. Uridine 5'-O-thiodiphosphate trisodium resists degradation by extracellular nucleotidases and stimulates the accumulation of inositol phosphates. Uridine 5'-O-thiodiphosphate trisodium stimulates contractile responses in endothelium-denuded rat mesenteric arteries. As a mitogen, Uridine 5'-O-thiodiphosphate trisodium stimulates DNA synthesis, [ 3H] thymidine incorporation, protein synthesis, [ 3H]leucine incorporation, and increases the number of vascular smooth muscle cells. Uridine 5'-O-thiodiphosphate trisodium can be used in the research of cardiovascular diseases such as atherosclerosis .
|
-
- HY-10822A
-
|
BGC 945 Trisodium; ONX 0801 Trisodium; CB 300945 Trisodium
|
Thymidylate Synthase
|
Cancer
|
|
Idetrexed (ONX 0801) trisodium is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed trisodium can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
|
-
- HY-177596A
-
|
Cp3C Trisodium
|
CCR
|
Others
|
|
Dicytidine 5′-triphosphate (Cp3C) trisodium is a cytosine-containing dinucleoside polyphosphate. Dicytidine 5′-triphosphate trisodium inhibits the intracellular accumulation of trans-resveratrol and trans-piceid. Dicytidine 5′-triphosphate trisodium induces the expression of CCR2 and upregulates the expression of PAL1 and 4CL1 .
|
-
- HY-148843
-
|
|
Fluorescent Dye
|
Others
|
|
D-Luciferin phosphate trisodium is a synthetic and bioluminescent substrate for firefly luciferase. D-Luciferin phosphate trisodium is dephosphorylated in the presence of alkaline phosphatase, releasing the free D-fluorescein. D-Luciferin phosphate trisodium is mainly used for highly sensitive detection of phosphatase .
|
-
- HY-137749A
-
|
2'-Deoxy-3'-MANT-ADP Trisodium
|
Biochemical Assay Reagents
|
Others
|
|
MANT-dADP (trisodium) (2'-Deoxy-3'-MANT-ADP (trisodium)) is a fluorescent nucleotide derivative, with an emission maximum of 453 nm upon excitation at 350 nm. MANT-dADP (trisodium) can decrease inositol phoshate formation in CHO-K1 cells that express human purinergic P2Y12 receptor. MANT-dADP (trisodium) can be studied in research on the interaction between cardiac troponin I and myofibrils .
|
-
- HY-160728A
-
|
3′-O-Azidomethyl dATP Trisodium
|
Biochemical Assay Reagents
|
Others
|
|
3′-O-N3-dATP trisodium (3′-O-Azidomethyl dATP trisodium) is the trisodium salt form of 3′-O-N3-dATP. 3′-O-N3-dATP trisodium is a modified nucleotide, which is utilized for DNA polymerase. 3′-O-N3-dATP trisodium acts as reversible terminator with enhanced raman scattering (SERS) at 2125 cm -1, which determines the DNA sequences continuously .
|
-
- HY-100921A
-
-
- HY-116290A
-
-
- HY-W250844A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.
|
-
- HY-B1610R
-
|
Trisodium citrate dihydrate (Standard); Citric acid Trisodium salt dihydrate (Standard)
|
Reference Standards
Bacterial
Endogenous Metabolite
Apoptosis
|
Infection
Cardiovascular Disease
Cancer
|
|
Sodium citrate (dihydrate) (Standard) is the analytical standard of Sodium citrate (dihydrate). This product is intended for research and analytical applications. Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .
|
-
- HY-B1610H
-
|
Trisodium citrate dihydrate (Pharmaceutical primary standard, USP)
|
Biochemical Assay Reagents
|
Others
|
|
Sodium citrate dihydrate, United States Pharmacopeia (USP) Reference Standard is an antacid used in studies to neutralize gastric acid. Sodium citrate dehydrate can also be used to prepare biological buffers. Sodium citrate dehydrate is a reference standard grade of the United States Pharmacopeia (USP) and a first-class pharmaceutical standard .
|
-
- HY-113049A
-
|
Phosphoenolpyruvate Trisodium
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Phosphoenolpyruvic acid (Phosphoenolpyruvate) trisodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid trisodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid trisodium also exhibits cytoprotective and anti-oxidative properties .
|
-
- HY-137682A
-
|
GpCp Trisodium
|
CD73
|
Cancer
|
|
GMPCP (GpCp) trisodium (Compound 7 trisodium) is a guanosine derivative is a CD73 inhibitor, with Kis of 1110 nM (rat soluble CD73) and 410 nM (human soluble CD73) respectively. GMPCP (GpCp) trisodium can be used for research of cancer .
|
-
- HY-137675A
-
|
|
ATP Synthase
|
Metabolic Disease
|
|
isoGDP (trisodium) is a GDP isomer. isoGDP (trisodium) is a phosphorylated form of crotonoside. isoGDP (trisodium) is an inhibitor of mitochondrial ATPase with an IC50 of 3 μM .
|
-
- HY-164839A
-
|
Clofarabine-DP Trisodium
|
DNA/RNA Synthesis
|
Cancer
|
|
Clofarabine-5'-diphosphate trisodium (Clofarabine-DP trisodium) is the trisodium salt form of Clofarabine-5'-diphosphate (HY-164839). Clofarabine-5'-diphosphate trisodium is the metabolite of Clofarabine (HY-A0005) by deoxycytidine kinase (dCK) phosphorylation. Clofarabine-5'-diphosphate trisodium can be further phorphorylated into Clofarabine-5'-triphosphate, and exhibits cytotoxicity in cancer cells through inhibition of DNA synthesis and DNA repair .
|
-
- HY-107837R
-
|
2-Phospho-L-ascorbic acid Trisodium (Standard)
|
Reference Standards
Phosphatase
Reactive Oxygen Species (ROS)
Endogenous Metabolite
|
Metabolic Disease
|
|
L-Ascorbic acid 2-phosphate (trisodium) (Standard) is the analytical standard of L-Ascorbic acid 2-phosphate (trisodium). This product is intended for research and analytical applications. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3].
|
-
- HY-177726
-
|
|
P2Y Receptor
|
Inflammation/Immunology
|
|
UTPU trisodium (Compound 19) is a selective P2Y6R agonist with an EC50 of 0.4 μM. UTPU trisodium can activate the intracellular calcium signaling pathway mediated by P2Y6. UTPU trisodium can be used for the research of inflammation .
|
-
- HY-137717A
-
|
|
CD73
|
Cancer
|
|
COPCP trisodium (Compound 7a) is a potent and selective ecto-5'-nucleotidase CD73 inhibitor. COPCP trisodium blocks CD73-mediated adenosine production, reducing the inhibitory effect of adenosine on immune cells. COPCP trisodium is promising for research of cancers .
|
-
- HY-112502D
-
|
Adenosine 5'-(α,β-methylene)diphosphate Trisodium
|
CD73
|
Cancer
|
|
MethADP (Adenosine 5'-(α,β-methylene)diphosphate) trisodium is a CD73 inhibitor. MethADP trisodium can be used for the research of ATP-adenosine pathway .
|
-
- HY-171899A
-
|
GroPI(4,5)P2 Trisodium; GPIP2 Trisodium
|
Calcium Channel
|
Others
|
|
Glycerophosphoinositol 4,5-diphosphate (GroPI(4,5)P2) trisodium is a slowly metabolized analog of InsP3. Glycerophosphoinositol 4,5-diphosphate trisodium has an EC50 of 1.228 μM for inducing calcium release, with a degradation time constant of 13 seconds. Glycerophosphoinositol 4,5-diphosphate trisodium can be used to study the effect of InsP3 degradation on calcium signal recovery .
|
-
- HY-113371AS
-
-
- HY-W009362S
-
|
|
Isotope-Labeled Compounds
Endogenous Metabolite
|
Others
|
|
DL-Isocitric acid- 13C4 (trisodium salt) is a 13C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
|
-
- HY-W127801
-
|
EDTA Trisodium hydrate
|
Biochemical Assay Reagents
|
Others
|
|
Ethylenediaminetetraacetic acid (trisodium hydrate) is a class of organic compounds containing carboxylic acid functional groups. It is commonly used as a chelating agent in various industrial and medical applications, especially in the food and pharmaceutical industries. Ethylenediaminetetraacetic acid (trisodium hydrate) has strong metal ion binding properties and can be used to chelate trace metals that may affect product quality or stability. In addition, it is used as an anticoagulant in blood collection tubes and as a stabilizer in some cosmetic and personal care products.
|
-
- HY-147338S
-
|
5-Methyl-CTP-d3 Trisodium
|
DNA/RNA Synthesis
Isotope-Labeled Compounds
|
Others
|
|
5-Methylcytidine 5′-triphosphate-d3 trisodium is the deuterium labeled 5-Methylcytidine 5’-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5′-triphosphate trisodium can apply in replacing unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells .
|
-
- HY-134991A
-
-
- HY-107093A
-
|
|
Apoptosis
|
Cancer
|
|
MBC-11 trisodium is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C. MBC-11 trisodium has the potential for tumor-induced bone disease (TIBD) research .
|
-
- HY-147338S2
-
|
5-Methyl-CTP-d8 Trisodium
|
Isotope-Labeled Compounds
|
Inflammation/Immunology
|
|
5-Methylcytidine 5'-triphosphate-d8 trisodium is the deuterium-labeled form of 5-Methylcytidine 5'-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5'-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5'-triphosphate trisodium can be used to replace unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells .
|
-
- HY-109559
-
|
Ca-DTPA Trisodium
|
Biochemical Assay Reagents
|
Others
|
|
Pentetate calcium trisodium (Ca-DTPA) forms stable chelates with metal ions by exchanging calcium for a metal of greater binding capacity .
|
-
- HY-W742180
-
-
- HY-W960552A
-
|
|
DNA/RNA Synthesis
|
Others
|
|
5-Methoxy-cytidine-5'-triphosphate trisodiumyes 5-Methoxycytidine-5'-Trisodium triphosphate.
|
-
- HY-171587A
-
|
|
HCV
|
Infection
|
|
3′-Deoxy CTP trisodium is the sodium salt form of 3′-Deoxy CTP (HY-171587). 3′-Deoxy CTP trisodium is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP trisodium can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP trisodium can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs .
|
-
- HY-141479A
-
|
Butyryl CoA Trisodium
|
Drug Intermediate
|
Others
|
|
Butyryl-Coenzyme A (Butyryl CoA) trisodium is a short-chain acyl CoA that can synthesize Butyric acid (HY-B0350) .
|
-
- HY-B1318R
-
|
Trisodium phosphonoformate (Standard); Phosphonoformic acid Trisodium salt (Standard)
|
DNA/RNA Synthesis
Reference Standards
|
Infection
|
|
Foscarnet (sodium) (Standard) is the analytical standard of Foscarnet (sodium). This product is intended for research and analytical applications. Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis .
|
-
- HY-B1610ER
-
|
Trisodium citrate dihydrate, meets USP testing specifications (Standard)
|
Reference Standards
Biochemical Assay Reagents
|
Cardiovascular Disease
|
|
Sodium citrate dihydrate, meets USP testing specifications (Standard) is the analytical standard of Sodium citrate dihydrate, meets USP testing specifications. This product is intended for research and analytical applications. Sodium citrate dihydrate, meets USP testing specifications is an anticoagulant and also used as a buffer and food preservatives .
|
-
- HY-137662A
-
|
pGpG Trisodium
|
STING
|
Metabolic Disease
|
|
5'-Phosphoguanylyl-(3',5')-guanosine trisodium (pGpG trisodium) is an intermediate molecule produced by the pathway for enzymatic cyclic diguanylate (c-di-GMP) degradation. 5'-Phosphoguanylyl-(3',5')-guanosine trisodium can be used to detect the metabolism of nucleic acids .
|
-
- HY-137615A
-
-
- HY-179540
-
|
5-BrUTP Trisodium
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
|
Others
|
|
5-Bromo-UTP (5-BrUTP) trisodium is a derivative of uridine triphosphate (UTP). 5-Bromo-UTP trisodium can be utilized by cells as a precursor for RNA synthesis. During transcription, it integrates into the newly synthesized RNA chain and replaces some UTP. 5-Bromo-UTP trisodium can be used to label newly synthesized RNA, thereby enabling high-resolution visualization of transcriptional sites and RNA transport .
|
-
- HY-125818D
-
-
- HY-W724319
-
|
Sodium citrate-d4; Trisodium citrate anhydrous-d4
|
Isotope-Labeled Compounds
Apoptosis
Bacterial
Endogenous Metabolite
|
Cardiovascular Disease
Infection
Metabolic Disease
Inflammation/Immunology
Cancer
|
|
Citric acid-d4 trisodium (Sodium citrate-d4) is the deuterium labeled Citric acid trisodium (HY-B2201). Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
|
-
- HY-137678A
-
|
|
Biochemical Assay Reagents
|
Others
|
|
GTP-γ-AmNS (trisodium) is a fluorescent derivative of GTP (λexc 320 nm; λem 460 nm). GTP-γ-AmNS (trisodium) can be used in assays of enzymes specialized to cleave α-β-phosphodiester bonds .
|
-
- HY-128036B
-
|
2',3'-Dideoxyadenosine 5'-triphosphate Trisodium
|
DNA/RNA Synthesis
HIV
|
Infection
|
|
ddATP (2',3'-Dideoxyadenosine 5'-triphosphate) trisodium, an active metabolite of 2',3'-dideoxyinosine, is a chain-elongating inhibitor of DNA polymerase. ddATP trisodium can be used for Sanger method for DNA sequencing and research of virus infection .
|
-
- HY-110369
-
|
a,β-Methylene-2-thio-UDP Trisodium
|
P2Y Receptor
|
Inflammation/Immunology
|
|
MRS2905 (α,β-Methylene-2-thio-UDP) trisodium is a selective P2Y14R agonist with an EC50 of 0.92 nM. MRS2905 trisodium is inactive at the UDP-activated P2Y6 receptor, and at other P2Y receptors .
|
-
- HY-B1533A
-
|
|
Fluorescent Dye
|
Others
|
|
Anazolene trisodium is an anionic dye, a textile azo dye with a maximum absorption wavelength of λmax = 571 nm .
|
-
- HY-125954B
-
-
- HY-D1022A
-
|
Biotin-16-deoxyuridine-5'-triphosphate Trisodium
|
DNA Stain
|
Others
|
|
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
|
-
- HY-128370
-
|
Ca-DTPA Trisodium salt hydrate
|
CMV
|
Infection
|
|
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication .
|
-
- HY-112732B
-
|
|
Apoptosis
|
Metabolic Disease
Cancer
|
|
Sparfosic acid trisodium is a DNA antimetabolite agent and a potent inhibitor of aspartate transcarbamoyl transferase. Aspartate transcarbamoyl transferase catalyzes the second step of de novo pyrimidine biosynthesis. Sparfosic acid trisodium synergistically enhances the cytotoxicity of a combination of 5-fluorouracil (5-FU) and interferon-alpha (IFN) against human colon cancer cell lines .
|
-
- HY-171632A
-
-
- HY-137607A
-
|
|
P2Y Receptor
|
Inflammation/Immunology
|
|
UMP-CP trisodium (Compound 3), a nucleotide, is a P2Y14 receptor agonist with an EC50 of 160 nM for P2Y14 receptor over the P2Y6 receptor. UDP trisodium can be used for pain, diabetes, cystic fibrosis and other pulmonary diseases research .
|
-
- HY-N18954
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Heparin disaccharide III-S trisodium (Compound SHH-7) is a heparin-derived disaccharide. Heparin disaccharide III-S trisodium acts as an inhibitor of spontaneous IL-8 and IL-1β secretion by intestinal epithelial cells. Heparin disaccharide III-S trisodium functions at the post-translational stage and does not reduce mRNA or intracellular mediator levels .
|
-
- HY-D1029A
-
-
- HY-108656A
-
|
|
P2Y Receptor
Arrestin
|
Cardiovascular Disease
|
|
MRS2365 trisodium is a potent and selective P2Y1 receptor (EC50=0.4 nM)/[ 35S]GTPγS binding/β-arrestin 2 recruitment agonist. MRS2365 trisodium relieves mechanical allodynia and increases mechanical sensitivity .
|
-
- HY-128788A
-
|
|
DNA/RNA Synthesis
SARS-CoV
Endogenous Metabolite
Flavivirus
Lactate Dehydrogenase
|
Infection
|
|
ddhCTP trisodium solution (100 mM) is an endogenously produced pyrimidine base analog with a Kd of 17.0 nM for LLDH and an IC50 of 55.8 μM for GAPDH. By inhibiting key metabolic enzymes such as GAPDH, ddhCTP trisodium reduces glycolytic flux and shifts metabolic flow toward the pentose phosphate pathway, thereby regulating the redox balance of cells. As a competitive CTP analog, ddhCTP trisodium terminates RNA synthesis by flavivirus RdRps and SARS-CoV-2 RdRp, and inhibits Zika virus replication in vivo. ddhCTP trisodium can be used in studies related to viral infections, COVID-19 and Zika virus infections .
|
-
- HY-117356B
-
|
|
P2Y Receptor
NF-κB
ERK
|
Cardiovascular Disease
|
|
MRS2693 trisodium is a selective P2Y6 agonist with an EC50 value of 0.015 μM. MRS2693 trisodium can reduce the activation of NF-kappaB and activate the ERK1/2 pathway, and has a cytoprotective effect on mouse hindlimb skeletal muscle ischemia-reperfusion injury model .
|
-
- HY-137615C
-
-
- HY-W040188
-
|
|
Biochemical Assay Reagents
|
Others
|
|
Fosfructose trisodium octahydrate is a phosphorylated sugar derivative used in biochemical research and is also an intermediate in carbohydrate metabolism.
|
-
- HY-134103A
-
|
2′,3′-Dideoxyguanosine 5′-triphosphate Trisodium
|
DNA/RNA Synthesis
|
Others
|
|
ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) trisodium (100 mM in water) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddGTP trisodium acts as an inhibitor or a substrate for DNA polymerase α .
|
-
- HY-D1199
-
|
|
P2X Receptor
P2Y Receptor
|
Inflammation/Immunology
|
|
Blue FPG-A trisodium is a selective antagonist of P2X1 receptor and P2Y1 receptor with IC50 values of 35.5 μM and 2.6 μM, respectively. Blue FPG-A trisodium is a structural isomer of the components of Reactive Blue 2 (RB2) .
|
-
- HY-W013715A
-
|
dTTP Trisodium solution (100 mM)
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Others
|
Deoxythymidine-5'-triphosphate (dTTP) (trisodium) solution (100 mM) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
|
-
- HY-W013706R
-
|
ITP Trisodium salt (Standard); Inosine triphosphate Trisodium salt (Standard)
|
Endogenous Metabolite
Reference Standards
|
Metabolic Disease
|
|
Inosine-5'-triphosphate (trisodium salt) (Standard) is the analytical standard of Inosine-5'-triphosphate (trisodium salt) (HY-W013706). This product is intended for research and analytical applications. Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
|
-
- HY-141567A
-
|
Pseudo-UTP Trisodium solution (100 mM)
|
DNA/RNA Synthesis
|
Infection
|
|
Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
|
-
- HY-134178A
-
-
- HY-175073
-
|
|
Toll-like Receptor (TLR)
Interleukin Related
|
Neurological Disease
Inflammation/Immunology
|
|
Ganglioside GT1b bovine trisodium is a trisialic acid ganglioside. Ganglioside GT1b bovine trisodium binds to botulinum toxin type A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 μM, respectively. Ganglioside GT1b bovine trisodium acts as a TLR2 agonist, leading to microglial activation, increased expression of pro-inflammatory factors, and increased pain sensitivity in spinal microglia. Ganglioside GT1b bovine trisodium also reduces the production of IL-6, IL-10, IgG, IgM, and IgA in human peripheral blood mononuclear cells (PBMCs). Ganglioside GT1b bovine trisodium increases extracellular glutamate levels in neural cell models. Ganglioside GT1b bovine trisodium has potential applications in research on immune system diseases and nervous system diseases .
|
-
- HY-N18953
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Heparin disaccharide I-H trisodium (Compound SHS-5) is a heparin-derived disaccharide. Heparin disaccharide I-H trisodium blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational stage without reducing mRNA expression levels or intracellular contents. Heparin disaccharide I-H trisodium exhibits dose-dependent anti-inflammatory activity in intestinal epithelial cell models .
|
-
- HY-W013111
-
|
dGDP Trisodium; 2'-Deoxyguanosine-5'-diphosphate Trisodium
|
Nucleoside Antimetabolite/Analog
Parasite
|
Infection
|
|
2′-Deoxy-GDP (dGDP) trisodium, a guanosine monophosphate (GMP) analogue, is a hypoxanthine phosphoribosyltransferase (HGPRT) inhibitor with an IC50 of 12.5 μM. HGPRT is a central enzyme in the purine recycling pathway of all protozoan parasites .
|
-
- HY-112582C
-
|
1-Methylpseudouridine-5′-triphosphate Trisodium; N1-Me-Pseudo UTP Trisodium; N1-Methyl-Pseudo-UTP Trisodium
|
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
|
Cardiovascular Disease
|
|
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
|
-
- HY-N11522A
-
|
5-Methyl-UTP Trisodium
|
DNA/RNA Synthesis
|
Others
|
|
5-Methyluridine-5'-triphosphate (5-Methyl-UTP) trisodium is a base modified ribonucleoside triphosphates, and can be used for in vitro transcription.
|
-
- HY-12695B
-
|
5'-GTP Trisodium salt hydrate
|
Exosomes
Endogenous Metabolite
DNA/RNA Synthesis
|
Metabolic Disease
|
|
Guanosine 5'-triphosphate (5'-GTP) trisodium salt hydrate is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt hydrate can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt hydrate holds promise for research in biosynthesis and skeletal muscle regeneration .
|
-
- HY-112817A
-
|
8-Oxo-Deoxyguanosine triphosphate Trisodium
|
Apoptosis
|
Others
|
|
8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) trisodium solution (100mM) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP trisodium solution (100mM) acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP trisodium solution (100mM) causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP trisodium solution (100mM) in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP trisodium solution (100mM) is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .
|
-
- HY-W697935
-
|
|
Drug Intermediate
|
Others
|
|
Sulfo-TAG COOH trisodium (Example 2) is a catalyst ligand that can be used for the synthesis of electrochemiluminescence (ECL) labels.
|
-
- HY-N18952
-
|
|
Interleukin Related
|
Inflammation/Immunology
|
|
Heparin disaccharide II-S trisodium (Compound HSH-9) is a heparin-derived disaccharide. Heparin disaccharide II-S trisodium inhibits the spontaneous secretion of proinflammatory mediators IL-8 and IL-1β in intestinal epithelial cells at the post-transcriptional stage .
|
-
- HY-172567
-
|
|
Biochemical Assay Reagents
Phospholipase
|
Others
|
|
PLC thio-PIP2 trisodium is an analog of naturally occurring PIP2. PLC thio-PIP2 trisodium can simulate the process of PIP2 being hydrolyzed by PLC in in vitro experiments, and then quantitatively analyze the activity of PLC by detecting the free thiol produced by hydrolysis .
|
-
- HY-N15801
-
-
- HY-137611A
-
|
|
DNA/RNA Synthesis
|
Cancer
|
|
α,β-MTDP trisodium, a thymidylate analog, is a thymidine kinase inhibitor with a Ki of 23 µM .
|
-
- HY-137593A
-
|
ε-NADP+ Trisodium
|
Drug Derivative
|
Metabolic Disease
|
|
N6-Etheno-nicotinamide dinucleotide phosphate (ε-NADP+) trisodium, a structural analogue of the NADP(+), is a maize malic enzyme inhibitor with a Ki of 1.01 μM .
|
-
- HY-W008915R
-
|
CDP (Standard)
|
Reference Standards
DNA/RNA Synthesis
|
Metabolic Disease
|
|
Cytidine 5'-diphosphate (trisodium salt) (Standard) is the analytical standard of Cytidine 5'-diphosphate (trisodium salt). This product is intended for research and analytical applications. Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA[1][2].
|
-
- HY-139262A
-
|
|
Reverse Transcriptase
HIV
HBV
HCV
|
Infection
|
|
FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV . FNC-TP (trisodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
|
-
- HY-113225H
-
|
Guanosine triphosphate Trisodium salt, 100 mM Solution, PCR Grade
|
Biochemical Assay Reagents
|
Cancer
|
|
GTP trisodium salt, 100 mM Solution, PCR Grade (Guanosine triphosphate trisodium salt, 100 mM Solution, PCR Grade) is a solution prepared from GTP at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, and suitable for molecular biology research .
|
-
- HY-D0031
-
|
APTS
|
Fluorescent Dye
|
Others
|
|
8-Aminopyrene-1,3,6-trisulfonic acid trisodium (APTS) is an anionic fluorescent dye (excitation/emission: 425/503 nm in pH 7.4 PBS). The fluorescence intensity of 8-Aminopyrene-1,3,6-trisulfonic acid trisodium remains stable at pH 4-10. 8-Aminopyrene-1,3,6-trisulfonic acid trisodium retains its fluorescence properties when immobilized in a hydrogel by copolymerization. 8-Aminopyrene-1,3,6-trisulfonic acid trisodium can be used for glucose sensing .
|
-
- HY-108652R
-
|
|
Reference Standards
P2X Receptor
|
Inflammation/Immunology
|
|
α,β-Methylene-ATP trisodium (Standard) is the analytical standard of α,β-Methylene-ATP (trisodium) (HY-108652). This product is intended for research and analytical applications. α,β-Methylene-ATP trisodium is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP trisodium can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP trisodium also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP trisodium can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system .
|
-
- HY-134393B
-
|
N6-Methyl-ATP Trisodium solution (100 mM)
|
GSK-3
|
Others
|
|
6-Me-ATP (N6-Methyl-ATP) trisodium solution (100 mM) is a N 6-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide .
|
-
- HY-108651
-
|
UTPγS Trisodium
|
P2Y Receptor
|
Metabolic Disease
|
|
Uridine-5'-O-(3-thiotriphosphate) trisodium, a stable analogue of UTP, is a potent agonist of the P2Y2 and P2Y4 receptors with increased metabolic stability .
|
-
- HY-137604A
-
|
|
Biochemical Assay Reagents
|
Infection
|
|
(γ-AmNS)UTP (trisodium) is a fluorescent derivative of UTP and enables the detection of RNA polymerase activity. Incorporation of UMP in RNA results in the release of γ-AmNS-PPi, which has higher intrinsic fluorescence than (γ-AmNS) UTP. (γ-AmNS)UTP (trisodium) can be used for antibacterial and antituberculosis agents study .
|
-
- HY-137733A
-
|
Cytidine-5'-O-2-thiodiphosphate Trisodium salt
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
CDP-β-S (Cytidine-5'-O-(2-thiodiphosphate)) trisodium salt is an unhydrolyzable analogue of CDP (Cytidine Diphosphate), featuring antioxidant and free radical scavenging functions .
|
-
- HY-W013715B
-
|
dTTP Trisodium,100 mM Solution,PCR Grade
|
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Endogenous Metabolite
|
Others
|
Deoxythymidine-5'-triphosphate (dTTP) trisodium, 100 mM Solution, PCR Grade is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate trisodium, 100 mM Solution, PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
|
-
- HY-134382A
-
|
7-Deaza-2'-deoxyadenosine-5'-O-diphosphate Trisodium
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
7-CH-dADP (7-Deaza-2'-deoxyadenosine-5'-O-diphosphate) trisodium is a dehydroxylated and deaminated derivative of the nucleotide ADP.
|
-
- HY-108652
-
|
|
P2X Receptor
|
Inflammation/Immunology
|
|
α,β-Methylene-ATP trisodium is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP trisodium can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP trisodium also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP trisodium can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system .
|
-
- HY-177605
-
|
|
DNA/RNA Synthesis
|
Others
|
|
ddNTP Set trisodium contains ddATP (HY-128036B), ddCTP (HY-137697D), ddGTP (HY-134103A), and ddTTP (HY-137694B).
|
-
- HY-134439
-
-
- HY-136648A
-
|
dATP Trisodium
|
Endogenous Metabolite
DNA/RNA Synthesis
|
Cancer
|
|
2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency .
|
-
- HY-131838A
-
|
6-AB-ADP Trisodium
|
Nucleoside Antimetabolite/Analog
DNA/RNA Synthesis
|
Others
|
|
N6-4-aminobutyl-ADP (6-AB-ADP) trisodium is an ADP derivative that can be used as a nucleotide mimetic or coupling agent for labeling enzyme substrates (such as kinases), constructing biological probes, or functionalizing nucleotide chains .
|
-
- HY-W009362AS
-
-
- HY-137694B
-
|
|
DNA/RNA Synthesis
|
Others
|
|
ddTTP trisodium solution (100 mM) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing .
|
-
- HY-139926S
-
-
- HY-W017068
-
|
2'-Deoxyuridine-5'-triphosphate Trisodium salt
|
DNA/RNA Synthesis
|
Others
|
|
dUTP trisodium (2´-Deoxyuridine, 5´-Triphosphate) is the salt form of dUTP. dUTP is a metabolic intermediate in both procaryotes and eucaryotes. dUTP can be used in PCR and RT-PCR to replace dTTP, resulting in the uracil-containing PCR products suitable for most standard applications. dUTP is found to inhibit the enzyme - Cytidine Aminohydrolase from sheep liver .
|
-
- HY-103642A
-
|
Inositol 1,4,5-trisphosphate Trisodium; Ins(1,4,5)-P3 Trisodium
|
Calcium Channel
|
Metabolic Disease
|
|
D-myo-Inositol-1,4,5-triphosphate sodium salt is the trisodium salt of D-myo-Inositol 1,4,5-trisphosphate (1,4,5-IP3), which is a second messenger that stimulates the discharge of calcium from the endoplasmic reticulum.
|
-
- HY-D0129
-
|
MPTS
|
Fluorescent Dye
|
Others
|
|
8-Methoxypyrene-1,3,6-trisulfonate trisodium (MPTS) is a highly water-soluble superpolar fluorescent probe .
|
-
- HY-173579
-
|
2'(3')-AEC-ADP Trisodium
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'(3')-O-(2-Aminoethylcarbamoyl)adenosine-5'-O-diphosphate (2'(3')-AEC-ADP) trisodium is a derivative of Adenosine 5'-diphosphate (ADP) (HY-W010918).
|
-
- HY-132146A
-
|
|
DNA/RNA Synthesis
|
Others
|
|
5-Propargylamino-ddCTP (trisodium) solution (25mM), a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis .
|
-
- HY-W013706
-
|
ITP Trisodium salt; Inosine triphosphate Trisodium salt
|
Endogenous Metabolite
|
Metabolic Disease
|
|
Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
|
-
- HY-W008915
-
|
CDP
|
DNA/RNA Synthesis
|
Metabolic Disease
|
|
Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .
|
-
- HY-175083
-
|
|
Drug Derivative
PI3K
|
Others
|
|
PtdIns-(4,5)-P2-biotin trisodium is a Biotin-labeled PtdIns-(4,5)-P2 analog. PtdIns-(4,5)-P2-biotin trisodium is an affinity probe of PI3Kγ. PI3Kγ can catalyse the phosphorylation of PtdIns-(4,5)-P2 at the 3′-OH group, giving rise to the second messenger PtdIns(3,4,5)-P3 .
|
-
- HY-D1119B
-
|
|
Fluorescent Dye
|
Others
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
-
- HY-147338S1
-
|
5-Methyl-CTP-15N2,13C Trisodium
|
DNA/RNA Synthesis
|
Others
|
|
5-Methylcytidine 5′-triphosphate- 15N2, 13C (5-Methyl-CTP- 15N2, 13C) trisodium is the 15N and 13C labled 5-Methylcytidine 5′-triphosphate (HY-147338). 5-Methylcytidine 5′-triphosphate is a modified nucleoside triphosphate .
|
-
- HY-158819
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium is a cap analog that can be used for in vitro transcription of mRNA.
|
-
- HY-185603
-
-
- HY-164192A
-
|
|
DNA/RNA Synthesis
|
Others
|
|
m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium, a cap analogue derived from patent WO2023159930A1, can be used for the synthesis of mRNA .
|
-
- HY-185617
-
-
- HY-107372H
-
|
Uridine 5'-triphosphate Trisodium salt, 100 mM Solution, PCR Grade
|
Biochemical Assay Reagents
Endogenous Metabolite
DNA/RNA Synthesis
P2Y Receptor
|
Cardiovascular Disease
|
|
UTP (Uridine 5'-triphosphate) trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .
|
-
- HY-106950AR
-
|
Diphosphofructose Trisodium (Standard); Esafosfan Trisodium (Standard); FDP Trisodium (Standard)
|
Reference Standards
Endogenous Metabolite
|
Cardiovascular Disease
|
|
Crassicauline A (Standard) is the analytical standard of Crassicauline A. This product is intended for research and analytical applications. Crassicauline A (Crassicaulin A) is a bioactive alkaloid found in roots of Aconitum carmichaeli. Crassicauline A (Crassicaulin A) possesses feeding deterrent activity against T. castaneum adults with an EC50 of 1134.5 ppm .
|
-
- HY-115740A
-
|
Ara-CTP Trisodium
|
DNA/RNA Synthesis
|
Cancer
|
|
Cytarabine triphosphate (Ara-CTP) trisodiu, an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate trisodiu levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine .
|
-
- HY-134353A
-
|
Adenosine 5'-(β-thiodiphosphate) Trisodium
|
Interleukin Related
P2Y Receptor
NF-κB
Caspase
|
Neurological Disease
Inflammation/Immunology
Cancer
|
|
ADP-β-S (Adenosine 5'-(β-thiodiphosphate)) trilithium is a non-hydrolyzable ADP analog and a P2Y12 receptor agonist. ADP-β-S trilithium activates the P2Y12 receptor in microglia, thereby triggering downstream inflammatory signaling pathways. ADP-β-S trilithium activates P2Y purinergic receptors in rat pancreatic β cells and enhances glucose-induced insulin secretion. ADP-β-S trilithium can be used in the research of diseases such as inflammation and diabetes .
|
-
- HY-164557A
-
|
3′-Deoxy-ATP Trisodium
|
DNA/RNA Synthesis
|
Others
|
|
3′-Deoxyadenosine 5′-triphosphate trisodiumCan be used for nucleic acid synthesis.
|
-
- HY-180450
-
|
|
Biochemical Assay Reagents
|
Cancer
|
|
Gadoxetate disodium is a liver-specific magnetic resonance imaging (MRI) contrast agent, can be used for detecting and identifying liver tumors .
|
-
- HY-E70263
-
|
|
Endogenous Metabolite
|
Metabolic Disease
|
|
04:1 Coenzyme A is a biochemical reagent that is a specific form of coenzyme A (CoA), "04:1" usually indicates that the acyl chain of the CoA contains four carbon atoms and one double bond. 04:1 Coenzyme A can be used to study specific biochemical reactions or pathways .
|
-
- HY-137697D
-
|
|
HIV
DNA/RNA Synthesis
Nucleoside Antimetabolite/Analog
Drug Metabolite
HIV Protease
|
Infection
|
|
ddCTP trilithium solution (100 mM) is a chain-terminating dideoxynucleotide. ddCTP trilithium is a type of chain-terminating deoxynucleotide. ddCTP trilithium can be incorporated into the extension primer chain that lacks the 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. ddCTP trilithium can distinguish almost identical RNA through distinguishable extension products in primer extension inhibition experiments. ddCTP trilithium is the active metabolite of Zalcitabine (HY-17392), which can competitively inhibit HIV reverse transcriptase, terminate the synthesis of viral DNA chains, and thereby inhibit HIV replication .
|
-
- HY-138615A
-
-
- HY-173533
-
|
2-Chloro TNP-Inosine 5'-triphosphate tetrasodium
|
Drug Derivative
|
Others
|
|
2-Chloro TNP-ITP (2-Chloro TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706) .
|
-
- HY-173531
-
|
8-Bromo TNP-Inosine 5'-triphosphate tetrasodium
|
Drug Derivative
|
Others
|
|
8-Bromo TNP-ITP (8-Bromo TNP-Inosine 5'-triphosphate) tetrasodium is an analog of Inosine-5'-triphosphate trisodium salt (HY-W013706) .
|
-
- HY-W010737
-
|
5'-GTP disodium salt
|
Exosomes
Endogenous Metabolite
MicroRNA
|
Metabolic Disease
|
|
Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
|
-
- HY-176025
-
|
3'-O-Pivaloyl dATP triethylammonium
|
Nucleoside Antimetabolite/Analog
|
Others
|
|
2'-Deoxy-3'-O-pivaloyladenosine-5'-O-triphosphate (3'-O-Pivaloyl dATP) triethylammonium is a derivative of
2'-Deoxyadenosine-5'-triphosphate trisodium (HY-136648A) .
|
-
| Cat. No. |
Product Name |
Type |
-
- HY-D1022A
-
|
Biotin-16-deoxyuridine-5'-triphosphate Trisodium
|
Fluorescent Dye
|
|
Biotin-16- dUTP (Biotin-16-deoxyuridine-5'-triphosphate) trisodium can be used to replace its natural counterpart dTTP by enzymatically incorporating it into DNA/cDNA. Biotin-16- dUTP trisodium can be used to produce biotinylated DNA probes in a variety of assay applications .
|
-
- HY-D1029A
-
|
|
Fluorescent Dye
|
|
Biotin-11-dUTP trisodium is a fluorescent substitute for dTTP.
|
-
- HY-B1533A
-
|
|
Fluorescent Dye
|
|
Anazolene trisodium is an anionic dye, a textile azo dye with a maximum absorption wavelength of λmax = 571 nm .
|
-
- HY-D1119B
-
|
|
Fluorescent Dye
|
|
AF647-NHS ester (trisodium) is an analogue of Alexa Fluor 647 (AF647) (HY-D1119). NHS ester can covalently bind to molecules with amino groups (such as proteins, antibodies, etc.). AF647 is a bright, far-red fluorescent dye with an excitation wavelength (λex) of 635 nm (conventional fluorescence detection)/620 nm (instantaneous detection). Storage: protect from light .
|
| Cat. No. |
Product Name |
Type |
-
- HY-B2201
-
|
Sodium citrate; Trisodium citrate anhydrous
|
Biochemical Assay Reagents
|
|
Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
|
-
- HY-112582C
-
|
1-Methylpseudouridine-5′-triphosphate Trisodium; N1-Me-Pseudo UTP Trisodium; N1-Methyl-Pseudo-UTP Trisodium
|
Biochemical Assay Reagents
|
|
N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is a nucleobase-modified nucleotide. N1-Methylpseudouridine-5′-triphosphate (1-Methylpseudouridine-5′-triphosphate) trisodium solution (100 mM) is used for synthesizing mRNA with reduced immunogenicity and improved stability .
|
-
- HY-B1610E
-
|
Trisodium citrate dihydrate, meets USP testing specifications
|
Biochemical Assay Reagents
|
|
Sodium citrate dihydrate, meets USP testing specifications is an anticoagulant and also used as a buffer and food preservatives .
|
-
- HY-100767
-
|
Guanosine 5'-[β,γ-imido]triphosphate Trisodium
|
Biochemical Assay Reagents
|
|
Guanylyl Imidodiphosphate (Guanosine 5'-[β,γ-imido]triphosphate) trisodium is a non-hydrolysable GTP analogue, an activator of ADP-ribosylation factor (ARF) and a potent stimulator of adenylate cyclase. Imidodiphosphate trisodium can be used in protein synthesis studies .
|
-
- HY-W040188
-
|
|
Biochemical Assay Reagents
|
|
Fosfructose trisodium octahydrate is a phosphorylated sugar derivative used in biochemical research and is also an intermediate in carbohydrate metabolism.
|
-
- HY-W013715A
-
|
dTTP Trisodium solution (100 mM)
|
Biochemical Assay Reagents
|
Deoxythymidine-5'-triphosphate (dTTP) (trisodium) solution (100 mM) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
|
-
- HY-113225H
-
|
Guanosine triphosphate Trisodium salt, 100 mM Solution, PCR Grade
|
Biochemical Assay Reagents
|
|
GTP trisodium salt, 100 mM Solution, PCR Grade (Guanosine triphosphate trisodium salt, 100 mM Solution, PCR Grade) is a solution prepared from GTP at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, and suitable for molecular biology research .
|
-
- HY-101400A
-
|
dCTP Trisodium solution (100 mM); 2′-Deoxycytidine-5′-triphosphate Trisodium solution (100 mM)
|
Biochemical Assay Reagents
|
|
Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100 mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .
|
-
- HY-W008661
-
|
dGTP Trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate Trisodium solution (100 mM)
|
Biochemical Assay Reagents
|
|
Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
|
-
- HY-136648A
-
|
dATP Trisodium
|
Biochemical Assay Reagents
|
|
2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency .
|
-
- HY-107372A
-
|
UTP Trisodium dihydrate; Uridine 5'-triphosphate Trisodium dihydrate
|
Biochemical Assay Reagents
|
|
Uridine triphosphate (trisodium dihydrate) (UTP (trisodium dihydrate); Uridine 5'-triphosphate (trisodium dihydrate)) is a biochemical reagent.
|
-
- HY-141567A
-
|
Pseudo-UTP Trisodium solution (100 mM)
|
Biochemical Assay Reagents
|
|
Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
|
-
- HY-137694B
-
|
|
Biochemical Assay Reagents
|
|
ddTTP trisodium solution (100 mM) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing .
|
-
- HY-Y1329
-
|
|
Biochemical Assay Reagents
|
|
Trisodium phosphate is a food additive. Trisodium phosphate affects the growth parameters (lag phase, maximum growth rate) of Listeria monocytogenes and increases the sensitivity of Gram-negative bacteria to Lysozyme (HY-P1068) and Nisin (HY-P1607) .
|
-
- HY-136648B
-
|
dATP Trisodium,100 mM Solution,PCR Grade
|
Biochemical Assay Reagents
|
2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade (dATP trisodium,100 mM Solution,PCR Grade) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. 2'-Deoxyadenosine-5'-triphosphate trisodium,100 mM Solution,PCR Grade is used in reverse transcription polymerase chain reaction (RT-PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
|
-
- HY-W017068B
-
|
2'-Deoxyuridine-5'-triphosphate Trisodium,100 mM Solution,PCR Grade
|
Biochemical Assay Reagents
|
|
dUTP trisodium,100 mM Solution,PCR Grade (2'-Deoxyuridine-5'-triphosphate trisodium,100 mM Solution,PCR Grade) is a highly stable nucleotide that can participate in the biosynthesis of DNA and is suitable for various conventional molecular biology experiments. This product is provided in the form of aqueous solution .
|
-
- HY-112581B
-
|
5-Methoxy-UTP Trisodium solution (100 mM); 5-OMe-UTP Trisodium solution (100 mM)
|
Biochemical Assay Reagents
|
|
5-Methoxyuridine 5'-triphosphate trisodium solution (100 mM) is a modified nucleotide triphosphate (NTP). 5-Methoxyuridine 5'-triphosphate trisodium can be added into mRNA with T7 RNA polymerase .
|
-
- HY-107372H
-
|
Uridine 5'-triphosphate Trisodium salt, 100 mM Solution, PCR Grade
|
Biochemical Assay Reagents
|
|
UTP (Uridine 5'-triphosphate) trisodium salt, 100 mM Solution, PCR Grade is a solution prepared from uridine triphosphate at a concentration of 100 mM, free of DNase, RNase and phosphatase contamination, suitable for molecular biology research. Uridine triphosphate (HY-107372) is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate activates membrane-bound P2Y2 receptors .
|
-
- HY-B1610I
-
|
Trisodium citrate dihydrate, for molecular biology
|
Biochemical Assay Reagents
|
|
Sodium citrate dihydrate, for molecular biology is an antacid used in studies to neutralize gastric acid. Sodium citrate dehydrate is often used to prepare biological buffers and can be used in molecular biology research .
|
-
- HY-W854659
-
|
Ce6 Trisodium
|
Biochemical Assay Reagents
|
|
Chlorin e6 Ce6 (trisodium) is a water-soluble derivative of chlorophyll, belonging to the chlorin class of photosensitizers with an absorption wavelength range of 600-670 nm. Chlorin e6 trisodium emits characteristic red fluorescence upon light excitation, enabling real-time identification of tumor boundaries and progression. Chlorin e6 trisodium can be used for the study of photodynamic therapy (PDT) of cancers (bladder cancer) and fluorescence diagnosis of neoplastic lesions .
|
-
- HY-W008661A
-
|
dGTP Trisodium,100 mM Solution,PCR Grade; 2'-Deoxyguanosine-5'-triphosphate Trisodium,100 mM Solution,PCR Grade
|
Biochemical Assay Reagents
|
|
Deoxyguanosine triphosphate (dGTP) trisodium,100 mM Solution,PCR Grade is one of the raw materials used by DNA polymerases to synthesize long DNA strands during DNA replication. Deoxyguanosine triphosphate trisodium,100 mM Solution,PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied in the form of an aqueous solution .
|
-
- HY-134393B
-
|
N6-Methyl-ATP Trisodium solution (100 mM)
|
Biochemical Assay Reagents
|
|
6-Me-ATP (N6-Methyl-ATP) trisodium solution (100 mM) is a N 6-modified ATP derivative. 6-Me-ATP trisodium shows excellent binding affinity to GSK3, serving as the phosphate group donor for GSK3β-catalyzed phosphorylation of its substrate peptide .
|
-
- HY-W013715B
-
|
dTTP Trisodium,100 mM Solution,PCR Grade
|
Biochemical Assay Reagents
|
Deoxythymidine-5'-triphosphate (dTTP) trisodium, 100 mM Solution, PCR Grade is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate trisodium, 100 mM Solution, PCR Grade is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
|
-
- HY-W088066A
-
|
|
Biochemical Assay Reagents
|
|
Trisodium phosphate dodecahydrate, 98% is an Antibacterial agent. Trisodium phosphate dodecahydrate, 98% reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate, 98% modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate, 98% is used in poultry processing .
|
-
- HY-W010771A
-
|
dCTP Trisodium,100 mM Solution,PCR Grade; 2′-Deoxycytidine-5′-triphosphate Trisodium,100 mM Solution,PCR Grade
|
Biochemical Assay Reagents
|
|
Deoxycytidine triphosphate (dCTP; 2′-Deoxycytidine-5′-triphosphate) trisodium,100 mM Solution,PCR Grade is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium,100 mM Solution,PCR Grade has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing. This product is supplied as an aqueous solution .
|
-
- HY-W145618
-
|
|
Biochemical Assay Reagents
|
|
Trisodium Glycyrrhizinate is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
|
-
- HY-132146A
-
|
|
Biochemical Assay Reagents
|
|
5-Propargylamino-ddCTP (trisodium) solution (25mM), a nucleoside molecule that can be used to synthesis of cyanine dye-nucleotide conjugate which is used in nucleic acid labeling or sequence analysis .
|
-
- HY-W127847
-
|
Triglycollamic acid Trisodium salt
|
Biochemical Assay Reagents
|
|
Nitrilotriacetic acid (Triglycollamic acid) trisodium salt is a chelating agent commonly used in various industrial processes, especially in the production of detergents, cleaners and metal plating solutions. Nitrilotriacetic acid trisodium salt has unique chemical properties that bind to metal ions, preventing them from reacting or precipitating out of solution.
|
-
- HY-W250844A
-
|
|
Biochemical Assay Reagents
|
|
DO3A (trisodium)is a bifunctional chelator (Bifunctional Chelator; BFC) and a macrocyclic DOTA derivative used for tumor pre-targeting. DO3A (trisodium) can be used for conjugation of peptides and radionuclides.
|
-
- HY-B1610H
-
|
Trisodium citrate dihydrate (Pharmaceutical primary standard, USP)
|
Biochemical Assay Reagents
|
|
Sodium citrate dihydrate, United States Pharmacopeia (USP) Reference Standard is an antacid used in studies to neutralize gastric acid. Sodium citrate dehydrate can also be used to prepare biological buffers. Sodium citrate dehydrate is a reference standard grade of the United States Pharmacopeia (USP) and a first-class pharmaceutical standard .
|
-
- HY-113049A
-
|
Phosphoenolpyruvate Trisodium
|
Biochemical Assay Reagents
|
|
Phosphoenolpyruvic acid (Phosphoenolpyruvate) trisodium is a glycolysis metabolite with a high-energy phosphate group. Phosphoenolpyruvic acid trisodium is involved in glycolysis and gluconeogenesis, and used as energy source to produce ATP, under the energy-limited conditions. Phosphoenolpyruvic acid trisodium also exhibits cytoprotective and anti-oxidative properties .
|
-
- HY-W011425A
-
|
Nitrilotris(methylenephosphonic acid), Trisodium salt
|
Biochemical Assay Reagents
|
|
NTPO trisodium is a DNA damage inducer, causing genomic DNA damage and fragmentation, activating ATR-mediated cell cycle checkpoints. The DNA damaging effects of NTPO trisodium are abrogated by base excision repair (BER) but not nucleotide excision repair (NER) .
|
-
- HY-W127801
-
|
EDTA Trisodium hydrate
|
Biochemical Assay Reagents
|
|
Ethylenediaminetetraacetic acid (trisodium hydrate) is a class of organic compounds containing carboxylic acid functional groups. It is commonly used as a chelating agent in various industrial and medical applications, especially in the food and pharmaceutical industries. Ethylenediaminetetraacetic acid (trisodium hydrate) has strong metal ion binding properties and can be used to chelate trace metals that may affect product quality or stability. In addition, it is used as an anticoagulant in blood collection tubes and as a stabilizer in some cosmetic and personal care products.
|
-
- HY-W742180
-
-
- HY-B1610ER
-
|
Trisodium citrate dihydrate, meets USP testing specifications (Standard)
|
Biochemical Assay Reagents
|
|
Sodium citrate dihydrate, meets USP testing specifications (Standard) is the analytical standard of Sodium citrate dihydrate, meets USP testing specifications. This product is intended for research and analytical applications. Sodium citrate dihydrate, meets USP testing specifications is an anticoagulant and also used as a buffer and food preservatives .
|
-
- HY-134439
-
| Cat. No. |
Product Name |
Category |
Target |
Chemical Structure |
-
- HY-113596
-
-
-
- HY-107837
-
-
-
- HY-W010737
-
-
-
- HY-W013093
-
-
-
- HY-W009362
-
-
-
- HY-12695
-
-
-
- HY-B1610
-
-
-
- HY-W011184
-
-
-
- HY-106950A
-
-
-
- HY-12688A
-
|
|
Structural Classification
Classification of Application Fields
Ketones, Aldehydes, Acids
Metabolic Disease
Endogenous metabolite
Disease Research Fields
Source Classification
Cancer
|
Mitochondrial Metabolism
Reactive Oxygen Species (ROS)
Amyloid-β
|
|
Succinyl phosphonate trisodium salt is a α-Ketoglutarate Dehydrogenase Complex (KGDHC) modulator with neuroprotective activity. Succinyl phosphonate trisodium salt protects this complex, reduces cellular succinyl-CoA concentration, downregulates protein succinylation levels, and inhibits the activity of the α-ketoglutarate dehydrogenase complex. Succinyl phosphonate trisodium salt corrects hypoxic or ethanol-induced behavioral impairments, modulates exploratory behavior and emotional stress responses, and improves hypoxia tolerance. Succinyl phosphonate trisodium salt reduces glutamate excitotoxicity, restores the activity of the α-ketoglutarate dehydrogenase complex, reverses the changes in glutamate dehydrogenase and glutamine synthetase activities induced by β-amyloid (Amyloid-β), modulates cognitive function, and prevents β-amyloid-induced neuronal damage. Succinyl phosphonate trisodium salt improves microglial senescence, alleviates neuroinflammation, reactive oxygen species (ROS) production, lipid peroxidation, and the expression of proinflammatory cytokines. Succinyl phosphonate trisodium salt can be used in the research of Alzheimer's disease, aging-related neuroinflammation, and Parkinson's disease .
|
-
-
- HY-W013706
-
|
ITP Trisodium salt; Inosine triphosphate Trisodium salt
|
Classification of Application Fields
Ketones, Aldehydes, Acids
Metabolic Disease
Endogenous metabolite
Disease Research Fields
Source Classification
|
Endogenous Metabolite
|
|
Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
|
-
-
- HY-17026E
-
|
dFdCTP Trisodium
|
Structural Classification
Natural Products
Classification of Application Fields
Endogenous metabolite
Disease Research Fields
Source Classification
Cancer
|
Drug Metabolite
DNA/RNA Synthesis
Apoptosis
|
|
Gemcitabine triphosphate (dFdCTP) trisodium is the active metabolite of Gemcitabine (HY-17026). The mechanism of Gemcitabine triphosphate trisodium cell-killing is its competition with cytidine triphosphate during DNA replication, which results in the inhibition of chain elongation. Gemcitabine triphosphate trisodium shows a Ki of 11.2 μM against DNA polymerase α and 14.4 μM against DNA polymerase ε. Gemcitabine triphosphate trisodium partially inhibits dCMP deaminase and acts as a substrate for DNA synthesis to incorporate into cellular DNA and RNA. Gemcitabine triphosphate trisodium disrupts DNA and RNA synthesis, arrests cell cycle in G0/G1 and S phases, triggers apoptosis, reduces tumor cell proliferation. Gemcitabine triphosphate trisodium can be used for the research of pancreatic cancer and non-small cell lung cancer .
|
-
-
- HY-W013715A
-
-
-
- HY-12695B
-
-
-
- HY-101400A
-
-
-
- HY-136648A
-
-
-
- HY-W008915
-
-
-
- HY-N8060A
-
-
-
- HY-135780A
-
-
-
- HY-136648AR
-
-
-
- HY-113371A
-
-
-
- HY-W009362R
-
-
-
- HY-W011184R
-
|
|
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
|
Reference Standards
Endogenous Metabolite
|
|
6-Phosphogluconic acid trisodium (Standard) is the analytical standard of 6-Phosphogluconic acid trisodium (HY-W011184). This product is intended for research and analytical applications. 6-Phosphogluconic acid trisodium is a potent and competitive phosphoglucose isomerase (PGI) inhibitor with Kis of 48 μM for glucose 6-phosphate and 42 μM for fructose 6-phosphate. 6-Phosphogluconic acid trisodium is an endogenous metabolite.
|
-
-
- HY-W008915R
-
-
-
- HY-106950AR
-
-
-
- HY-W013093R
-
-
-
- HY-B1610R
-
|
Trisodium citrate dihydrate (Standard); Citric acid Trisodium salt dihydrate (Standard)
|
Structural Classification
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
|
Reference Standards
Bacterial
Endogenous Metabolite
Apoptosis
|
|
Sodium citrate (dihydrate) (Standard) is the analytical standard of Sodium citrate (dihydrate). This product is intended for research and analytical applications. Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .
|
-
-
- HY-138615A
-
-
-
- HY-107837R
-
|
2-Phospho-L-ascorbic acid Trisodium (Standard)
|
Structural Classification
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
|
Reference Standards
Phosphatase
Reactive Oxygen Species (ROS)
Endogenous Metabolite
|
|
L-Ascorbic acid 2-phosphate (trisodium) (Standard) is the analytical standard of L-Ascorbic acid 2-phosphate (trisodium). This product is intended for research and analytical applications. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) is a long-acting vitamin C derivative that can stimulate collagen formation and expression[1]. L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) can be used as a culture medium supplement for the osteogenic differentiation of human adipose stem cells (hASCs). L-Ascorbic acid 2-phosphate trisodium (2-Phospho-L-ascorbic acid trisodium) increases alkaline phosphatase (ALP) activity and expression of runx2A in hASCs during the osteogenic differentiation[2][3].
|
-
-
- HY-N18954
-
-
-
- HY-W013706R
-
|
ITP Trisodium salt (Standard); Inosine triphosphate Trisodium salt (Standard)
|
Structural Classification
Ketones, Aldehydes, Acids
Endogenous metabolite
Source Classification
|
Endogenous Metabolite
Reference Standards
|
|
Inosine-5'-triphosphate (trisodium salt) (Standard) is the analytical standard of Inosine-5'-triphosphate (trisodium salt) (HY-W013706). This product is intended for research and analytical applications. Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
|
-
-
- HY-N18953
-
|
|
Structural Classification
Natural Products
Endogenous metabolite
Source Classification
|
Interleukin Related
|
|
Heparin disaccharide I-H trisodium (Compound SHS-5) is a heparin-derived disaccharide. Heparin disaccharide I-H trisodium blocks the spontaneous secretion of IL-8 and IL-1β in intestinal epithelial cells at the post-translational stage without reducing mRNA expression levels or intracellular contents. Heparin disaccharide I-H trisodium exhibits dose-dependent anti-inflammatory activity in intestinal epithelial cell models .
|
-
-
- HY-N18952
-
-
-
- HY-N15801
-
-
| Cat. No. |
Product Name |
Chemical Structure |
-
- HY-113371AS
-
|
|
|
2-Methylcitric acid-d3 (Methylcitric acid-d3) trisodium is deuterium-labeled 2-Methylcitric acid (trisodium) (HY-113371A) .
|
-
-
- HY-W009362S
-
|
|
|
DL-Isocitric acid- 13C4 (trisodium salt) is a 13C labeled DL-Isocitric acid (trisodium salt) (HY-W009362). DL-Isocitric acid trisodium salt is an endogenous metabolite. DL-Isocitric acid trisodium salt is a substrate in the citric acid cycle. DL-Isocitric acid trisodium salt can be used as a marker for determining the composition of isocitrates in fruit products, including fruit juices.
|
-
-
- HY-147338S
-
|
|
|
5-Methylcytidine 5′-triphosphate-d3 trisodium is the deuterium labeled 5-Methylcytidine 5’-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5′-triphosphate trisodium can apply in replacing unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells .
|
-
-
- HY-147338S2
-
|
|
|
5-Methylcytidine 5'-triphosphate-d8 trisodium is the deuterium-labeled form of 5-Methylcytidine 5'-triphosphate trisodium (HY-147338A). 5-Methylcytidine 5'-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5'-triphosphate trisodium can be used to replace unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells .
|
-
-
- HY-W009362AS
-
|
|
|
DL-Isocitric acid-13C4 (trisodium hydrate) is a 13C labeled DL-Isocitric acid.
|
-
-
- HY-139926S
-
|
|
|
PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (trisodium) is the deuterium labeled PtdIns-(4,5)-P2 (1,2-dipamitoyl) trisodium .
|
-
-
- HY-147338S1
-
|
|
|
5-Methylcytidine 5′-triphosphate- 15N2, 13C (5-Methyl-CTP- 15N2, 13C) trisodium is the 15N and 13C labled 5-Methylcytidine 5′-triphosphate (HY-147338). 5-Methylcytidine 5′-triphosphate is a modified nucleoside triphosphate .
|
-
-
- HY-W724319
-
|
|
|
Citric acid-d4 trisodium (Sodium citrate-d4) is the deuterium labeled Citric acid trisodium (HY-B2201). Citric acid trisodium (Sodium citrate) is a natural preservative and food tartness enhancer. Citric acid trisodium induces apoptosis and cell cycle arrest at G2/M phase and S phase in HaCaT cells. Citric acid trisodium cause oxidative damage of the liver by means of the decrease of antioxidative enzyme activities. Citric acid trisodium is also an acidulant, emulsifier, sequestrant and buffering agent widely used across many industries .
|
-
| Cat. No. |
Product Name |
|
Classification |
-
- HY-10822A
-
|
BGC 945 Trisodium; ONX 0801 Trisodium; CB 300945 Trisodium
|
|
Alkynes
|
|
Idetrexed (ONX 0801) trisodium is a thymidylate synthase (TS) inhibitor with a Ki of 1.2 nM. Idetrexed trisodium can be specifically transported into α-folate receptor (α-FR)-overexpressing tumors, such as ovarian cancer .
|
-
- HY-139262A
-
|
|
|
Azide
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FNC-TP trisodium is the intracellular active form of FNC. FNC is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV . FNC-TP (trisodium) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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| Cat. No. |
Product Name |
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Classification |
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- HY-W010737
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5'-GTP disodium salt
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Nucleotide Analogs
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
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- HY-W013093
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UTP Trisodium salt; Uridine 5'-triphosphate Trisodium salt
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Nucleotide Analogs
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Uridine triphosphate (UTP) trisodium salt is a pyrimidine nucleoside triphosphate that is used as a substrate to synthesize RNA or as an energy source in metabolic reactions. Uridine triphosphate trisodium salt activates membrane-bound P2Y2 receptors .
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- HY-12695
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5'-GTP Trisodium
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Nucleotide Analogs
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate trisodium salt holds promise for research in biosynthesis and skeletal muscle regeneration .
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- HY-W013706
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ITP Trisodium salt; Inosine triphosphate Trisodium salt
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Nucleotide Analogs
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Inosine-5'-triphosphate trisodium salt is a nucleotide analogue that acts on multiple G proteins and is widely used in G protein-related research. It can bind to the α -subunit of G proteins and participate in G protein-mediated signal transduction as a substitute for GTP. Its mechanism of action is to interact with the nucleotide-binding site of the G protein α -subunit, affecting the activity and function of G proteins. In the research field, it is mainly used to explore the role of the G protein signaling pathway in cellular physiological and pathological processes. For example, in HL-60 leukemia cells, its impact on G protein-mediated signal transduction can be studied .
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- HY-W013715A
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dTTP Trisodium solution (100 mM)
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Nucleotide Analogs
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Deoxythymidine-5'-triphosphate (dTTP) (trisodium) solution (100 mM) is one of the raw materials used by DNA polymerase to synthesize long DNA strands during DNA replication. Deoxythymidine-5'-triphosphate (trisodium) solution (100 mM) is used in polymerase chain reaction (PCR) for DNA amplification. This product is supplied as an aqueous solution.
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- HY-12695B
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5'-GTP Trisodium salt hydrate
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Nucleotide Analogs
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Guanosine 5'-triphosphate (5'-GTP) trisodium salt hydrate is a G protein (G proteins) signaling activator and a high-energy precursor in the biosynthesis of nucleotide units in DNA and RNA. Guanosine 5'-triphosphate trisodium salt hydrate can promote myogenic cell differentiation by upregulating miRNA (miR133a, miR133b) and myogenic regulatory factor expression, and by inducing human myogenic precursor cells to release exosomes containing guanosine molecules. Guanosine-5'-triphosphate disodium salt hydrate holds promise for research in biosynthesis and skeletal muscle regeneration .
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- HY-101400A
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dCTP Trisodium solution (100 mM); 2′-Deoxycytidine-5′-triphosphate Trisodium solution (100 mM)
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Nucleotide Analogs
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Deoxycytidine triphosphate trisodium (dCTP trisodium) solution (100 mM) is a nucleoside triphosphate that can be used for DNA synthesis. Deoxycytidine triphosphate trisodium salt has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing .
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- HY-W088066
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pH Modifiers
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Trisodium phosphate dodecahydrate is an Antibacterial agent. Trisodium phosphate dodecahydrate reduces the counts of Escherichia coli O157:H7 and Salmonella typhimurium attached to the surfaces of beef fat and fascia. Trisodium phosphate dodecahydrate modulates the growth parameters of Listeria monocytogenes in vitro: low concentrations shorten the lag phase and increase the maximum growth rate, while high concentrations prolong the lag phase and decrease the maximum growth rate. Trisodium phosphate dodecahydrate is used in poultry processing .
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- HY-W008661
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dGTP Trisodium solution (100 mM); 2'-Deoxyguanosine-5'-triphosphate Trisodium solution (100 mM)
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Nucleotide Analogs
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Deoxyguanosine triphosphate (dGTP) trisodium solution (100 mM) is a nucleotide precursor in cells for DNA synthesis. Deoxyguanosine triphosphate trisodium salt is used in reverse transcription-polymerase chain reaction (RT-PCR) for DNA amplification .
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- HY-136648A
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dATP Trisodium
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Nucleotide Analogs
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2'-Deoxyadenosine-5'-triphosphate (dATP) trisodium is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate is promising for research of genetic immunodeficiency diseases adenosine deaminase deficiency and purine nucleotide phosphorylase deficiency .
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- HY-W008915
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CDP
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Nucleotide Analogs
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Cytidine 5'-diphosphate trisodium salt (CDP) is produced by the transfer of phosphoryl group from ATP to cytidine monophosphate (CMP) catalyzed by uridine monophosphate kinase (UMPK). Cytidine 5′-diphosphate can be used to produce Cytidine triphosphate (CTP) for synthesis of DNA and RNA .
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- HY-147338A
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5-Methyl-CTP Trisodium
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Nucleotide Analogs
Cytidine Nucleotide
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5-Methylcytidine 5′-triphosphate (5-Methyl-CTP) trisodium is a modified nucleoside triphosphate. 5-Methylcytidine 5′-triphosphate trisodium can apply in replacing unmodified mRNA, resulting in the increase of translational properties and stability, as well as the reduction of innate immune responses in human and other mammalian cells .
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- HY-134103A
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2′,3′-Dideoxyguanosine 5′-triphosphate Trisodium
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Nucleotide Analogs
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ddGTP (2′,3′-Dideoxyguanosine 5′-triphosphate) trisodium (100 mM in water) is one of 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs) that acts as chain-elongating inhibitor of DNA polymerase for DNA sequencing. ddGTP trisodium acts as an inhibitor or a substrate for DNA polymerase α .
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- HY-141567A
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Pseudo-UTP Trisodium solution (100 mM)
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Nucleotide Analogs
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Pseudouridine 5'-triphosphate (Pseudo-UTP) trisodium solution (100 mM) is a modified ribonucleoside triphosphate and uracil base-modified UTP derivative. Pseudouridine 5'-triphosphate trisodium solution (100 mM) enhances translational properties and stability of mRNA, reduces innate immune responses in mammalian cells, and inhibits signal-dependent transcription termination of vaccinia virus early gene transcription while supporting transcription elongation. Pseudouridine 5'-triphosphate trisodium solution (100 mM) can be used for the research of vaccinia virus infection .
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- HY-137697D
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Nucleotide Analogs
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ddCTP trilithium solution (100 mM) is a chain-terminating dideoxynucleotide. ddCTP trilithium is a type of chain-terminating deoxynucleotide. ddCTP trilithium can be incorporated into the extension primer chain that lacks the 3'-hydroxyl group, thereby terminating primer extension, viral genome replication, and DNA synthesis. ddCTP trilithium can distinguish almost identical RNA through distinguishable extension products in primer extension inhibition experiments. ddCTP trilithium is the active metabolite of Zalcitabine (HY-17392), which can competitively inhibit HIV reverse transcriptase, terminate the synthesis of viral DNA chains, and thereby inhibit HIV replication .
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- HY-W010861
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- HY-134178A
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5-Fluorouridine-5'-triphosphate Trisodium
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Nucleotide Analogs
Uracil Nucleotide
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5-F-UTP (5-Fluorouridine-5'-triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis.
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- HY-177596A
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Cp3C Trisodium
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Nucleotide Analogs
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Dicytidine 5′-triphosphate (Cp3C) trisodium is a cytosine-containing dinucleoside polyphosphate. Dicytidine 5′-triphosphate trisodium inhibits the intracellular accumulation of trans-resveratrol and trans-piceid. Dicytidine 5′-triphosphate trisodium induces the expression of CCR2 and upregulates the expression of PAL1 and 4CL1 .
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- HY-158819
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Cap Analogs
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m7(3'OMeG)(5')ppp(5')m6(2'OMeA)pG trisodium is a cap analog that can be used for in vitro transcription of mRNA.
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- HY-164192A
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Cap Analogs
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m7(3'AcmG)(5')ppp(5')(2'OMeA)pG trisodium, a cap analogue derived from patent WO2023159930A1, can be used for the synthesis of mRNA .
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- HY-138615A
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dTTP sodium hydrate
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Nucleotide Analogs
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Deoxythymidine-5'-triphosphate (dTTP) sodium hydrate is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate trisodium salt is used in the synthesis of DNA .
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- HY-W960552A
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- HY-N11522A
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5-Methyl-UTP Trisodium
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Nucleotide Analogs
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5-Methyluridine-5'-triphosphate (5-Methyl-UTP) trisodium is a base modified ribonucleoside triphosphates, and can be used for in vitro transcription.
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- HY-164557A
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- HY-176025
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3'-O-Pivaloyl dATP triethylammonium
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Nucleotide Analogs
Adenine Nucleotide
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2'-Deoxy-3'-O-pivaloyladenosine-5'-O-triphosphate (3'-O-Pivaloyl dATP) triethylammonium is a derivative of
2'-Deoxyadenosine-5'-triphosphate trisodium (HY-136648A) .
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- HY-125818D
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Cytidine triphosphate Trisodium; 5'-CTP Trisodium
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Nucleoside Analogs
Nucleotide Analogs
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Cytidine-5'-triphosphate (Cytidine triphosphate) trisodium is a monomeric raw material that can be used for nucleic acid synthesis.
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- HY-112817A
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8-Oxo-Deoxyguanosine triphosphate Trisodium
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Nucleotide Analogs
Guanine Nucleotide
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8-Oxo-dGTP (8-Oxo-Deoxyguanosine triphosphate) trisodium solution (100mM) is an oxidized guanine nucleotide formed by ROS-mediated oxidative modification of dGTP, and it also serves as a key substrate for 8-oxo-dGTP pyrophosphohydrolases (such as hMTH1 and E. coli MutT). 8-Oxo-dGTP trisodium solution (100mM) acts as a DNA mutagen, inserts into nascent DNA and pairs with adenine and cytosine, inducing A:T to C:G transversion mutations. Furthermore, 8-Oxo-dGTP trisodium solution (100mM) causes oxidative DNA base modification, strand breakage and S-phase arrest, and ultimately triggers AIF-mediated apoptosis and promotes spontaneous carcinogenesis in mth1-deficient mice. Accumulation of 8-Oxo-dGTP trisodium solution (100mM) in cells induces genomic instability, but it exhibits a tumor-suppressive effect that reduces tumor incidence in mouse models instead. 8-Oxo-dGTP trisodium solution (100mM) is widely used in studies related to spontaneous carcinogenesis, Parkinson's disease, Alzheimer's disease, heart failure and tumor mechanisms .
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- HY-158572
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Phospholipids
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PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (trisodium) is a phosphoinositide. Phosphoinositides (PI) are similar to other phospholipids, but the head group is the cyclic myo-inositol.
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