1. Foscarnet sodium

Foscarnet sodium  (Synonyms: Trisodium phosphonoformate; Phosphonoformic acid trisodium salt)

Cat. No.: HY-B1318 Purity: ≥99.0%
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Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis.

For research use only. We do not sell to patients.

Foscarnet sodium Chemical Structure

Foscarnet sodium Chemical Structure

CAS No. : 63585-09-1

Size Price Stock Quantity
Solid + Solvent
10 mM * 1 mL in Water
ready for reconstitution
USD 55 In-stock
Solution
10 mM * 1 mL in Water USD 55 In-stock
Solid
50 mg USD 50 In-stock
100 mg USD 80 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of Foscarnet sodium:

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Description

Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3].

In Vitro

Foscarnet sodium (Trisodium phosphonoformate) inhibits Influenza A Victoria (IC50=29 μM), Influenza B HK (IC50=61 μM), and Avian myeloblastosis virus (IC50=5-8 μM),HSV-1, several strains (IC50=0.4-3.5 μM)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

191.95

Formula

CNa3O5P

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=P(O[Na])(O[Na])C(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 60 mg/mL (312.58 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2097 mL 26.0485 mL 52.0969 mL
5 mM 1.0419 mL 5.2097 mL 10.4194 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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(per animal)

g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥99.0%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.2097 mL 26.0485 mL 52.0969 mL 130.2423 mL
5 mM 1.0419 mL 5.2097 mL 10.4194 mL 26.0485 mL
10 mM 0.5210 mL 2.6048 mL 5.2097 mL 13.0242 mL
15 mM 0.3473 mL 1.7366 mL 3.4731 mL 8.6828 mL
20 mM 0.2605 mL 1.3024 mL 2.6048 mL 6.5121 mL
25 mM 0.2084 mL 1.0419 mL 2.0839 mL 5.2097 mL
30 mM 0.1737 mL 0.8683 mL 1.7366 mL 4.3414 mL
40 mM 0.1302 mL 0.6512 mL 1.3024 mL 3.2561 mL
50 mM 0.1042 mL 0.5210 mL 1.0419 mL 2.6048 mL
60 mM 0.0868 mL 0.4341 mL 0.8683 mL 2.1707 mL
80 mM 0.0651 mL 0.3256 mL 0.6512 mL 1.6280 mL
100 mM 0.0521 mL 0.2605 mL 0.5210 mL 1.3024 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Foscarnet sodium
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