1. Anti-infection
    Cell Cycle/DNA Damage
  2. Virus Protease
    DNA/RNA Synthesis
  3. Foscarnet sodium

Foscarnet sodium (Synonyms: Trisodium phosphonoformate; Phosphonoformic acid trisodium salt)

Cat. No.: HY-B1318 Purity: >98.0%
Handling Instructions

Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis.

For research use only. We do not sell to patients.

Foscarnet sodium Chemical Structure

Foscarnet sodium Chemical Structure

CAS No. : 63585-09-1

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Free Sample (0.5-1 mg)   Apply Now  
10 mM * 1  mL in Water USD 77 In-stock
Estimated Time of Arrival: December 31
50 mg USD 70 In-stock
Estimated Time of Arrival: December 31
100 mg USD 90 In-stock
Estimated Time of Arrival: December 31
250 mg USD 150 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Foscarnet sodium (Trisodium phosphonoformate) is a viral DNA polymerase activity inhibitor, leading to reversible suppression of viral replication. Foscarnet sodium is an antiherpesvirus agent used in cytomegalovirus retinitis[1][2][3].

In Vitro

Foscarnet sodium (Trisodium phosphonoformate) inhibits Influenza A Victoria (IC50=29 μM), Influenza B HK (IC50=61 μM), and Avian myeloblastosis virus (IC50=5-8 μM),HSV-1, several strains (IC50=0.4-3.5 μM)[2].

Molecular Weight

191.95

Formula

CNa₃O₅P

CAS No.

63585-09-1

SMILES

O=P(O[Na])(O[Na])C(O[Na])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 60 mg/mL (312.58 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.2097 mL 26.0485 mL 52.0969 mL
5 mM 1.0419 mL 5.2097 mL 10.4194 mL
10 mM 0.5210 mL 2.6048 mL 5.2097 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

FoscarnetTrisodium phosphonoformatePhosphonoformic acid trisodiumVirus ProteaseDNA/RNA SynthesisviralDNApolymerasereversiblesuppressionreplicationantiherpesviruscytomegalovirusretinitisInhibitorinhibitorinhibit

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Foscarnet sodium
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