![1,1′-Ethylidenebis[L-tryptophan]](https://file.medchemexpress.com/product_pic/hy-w585843.gif "Click to View 1,1′-Ethylidenebis[L-tryptophan] Product Detail")
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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Tryptophanyl-tRNA synthetase
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Tryptophanyl-tRNA synthetase" in MCE Product Catalog:
Cat. No.: HY-117319
CAS No.: 21200-24-8
Synonyms: TAK-083; PA-155A
Category:
Target:
Cat. No.: HY-W585843
CAS No.: 132685-02-0
Research Areas:
1,1′-Ethylidenebis[L-tryptophan] is an orally active amino acid analog. 1,1′-Ethylidenebis[L-tryptophan] promotes the release of adrenocorticotropic hormone and corticosterone in rat plasma, and transiently inhibits CRH mRNA in the paraventricular nucleus of the hypothalamus via glucocorticoid negative feedback. 1,1′-Ethylidenebis[L-tryptophan] induces multi-tissue inflammation and fibrosis in rodents and human cells, increases the number of degranulated mast cells, and activates the IL-5 pathway in lymphocytes. 1,1′-Ethylidenebis[L-tryptophan] is activated by tryptophanyl-tRNA synthetase and replaces L-tryptophan during translation; it also interferes with tryptophan metabolism in mice via the kynurenine pathway and dynamically alters their plasma quinolinic acid levels. 1,1′-Ethylidenebis[L-tryptophan] can be used for studies on metabolism-related mechanisms .
Cat. No.: HY-P71134
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: WARS1; Tryptophanyl-tRNA synthetase 1; IFI53; WARS; IFP53; Tryptophan--tRNA Ligase, Cytoplasmic; Tryptophanyl-tRNA synthetase; Tryptophan tRNA Ligase 1, Cytoplasmic; Interferon-Induced Protein 53; TrpRS; HWRS; Epididymis Secretory Sperm Binding Protein; T
Species:
Human
Source:
E. coli
Cat. No.: HY-P73540
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: WARS1; Tryptophanyl-tRNA synthetase 1; IFI53; WARS; IFP53; Tryptophan--tRNA Ligase, Cytoplasmic; Tryptophanyl-tRNA synthetase; Tryptophan tRNA Ligase 1, Cytoplasmic; Interferon-Induced Protein 53; TrpRS; HWRS; Epididymis Secretory Sperm Binding Protein; T
Species:
Human
Source:
Sf9 insect cells
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
