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Xanthium sibiricum

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Insecticide (1) Methionine Adenosyltransferase (MAT) (1) Reference Standards (1)
By Research Areas:	Neurological Disease (1)

Inhibitors & Agonists

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N8485

Pungiolide A	Others	Others
Pungiolide A is a sesquiterpene lactones that can be isolated from Xanthium sibiricum .

HY-N4035

Hop-17(21)-en-3-ol (3β)-A'-Neogammacer-17(21)-en-3-ol	Others	Others
Hop-17(21)-en-3-ol ((3β)-A'-Neogammacer-17(21)-en-3-ol) is a Monoterpenoids product that can be isolated from the herbs of Xanthium sibiricum .

HY-B0887BR

(-)-trans-Permethrin (Standard) (-)-trans-NRDC-143 (Standard); (1S)-trans-Permethrin (Standard)	Insecticide Reference Standards	Others
Atractyloside (potassium salt) (Standard) is the analytical standard of Atractyloside (potassium salt). This product is intended for research and analytical applications. Atractyloside potassium salt is a toxic diterpenoid glycoside that can be isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart .

HY-N1837

3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide	Others	Others
3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide is a Sesquiterpenoids product that can be isolated from the roots of Xanthium sibiricum .

HY-N8740

ent-16β,17-Dihydroxy-9(11)-kauren-19-oic acid	Others	Others
ent-16β,17-Dihydroxy-9(11)-kauren-19-oic acid is a Diterpenoids product that can be isolated from the herbs of Xanthium sibiricum Patrin .

HY-182303

Carboxyatractyloside CATR	Methionine Adenosyltransferase (MAT)	Neurological Disease
Carboxyatractyloside (CATR) is a tight-binding inhibitor of adenine nucleotide translocase, and represents the major toxic component of Xanthium sibiricum. Carboxyatractyloside competes with ADP for binding to the translocase, blocks the translocation of ADP/ATP across the inner mitochondrial membrane, and thereby inhibits ADP-stimulated respiration. In the presence of Cyclosporin A (HY-B0579), Carboxyatractyloside still induces permeability transition in liver mitochondria of aged rats, exhibiting significant hepatotoxicity and nephrotoxicity. Carboxyatractyloside is widely used in studies related to hepatotoxicity, nephrotoxicity and Alzheimer's disease .

Pungiolide A	Terpenoids Pterocarpus soyauxii Taub. Sesquiterpenes Plants Compositae Source Classification	Others
Pungiolide A is a sesquiterpene lactones that can be isolated from Xanthium sibiricum .

Hop-17(21)-en-3-ol (3β)-A'-Neogammacer-17(21)-en-3-ol	Triterpenes Gentiana scabra Bunge Terpenoids Gentianaceae Plants Source Classification	Others
Hop-17(21)-en-3-ol ((3β)-A'-Neogammacer-17(21)-en-3-ol) is a Monoterpenoids product that can be isolated from the herbs of Xanthium sibiricum .

(-)-trans-Permethrin (Standard) (-)-trans-NRDC-143 (Standard); (1S)-trans-Permethrin (Standard)	Microorganisms Source Classification	Insecticide Reference Standards
Atractyloside (potassium salt) (Standard) is the analytical standard of Atractyloside (potassium salt). This product is intended for research and analytical applications. Atractyloside potassium salt is a toxic diterpenoid glycoside that can be isolated from the fruits of Xanthium sibiricum. Atractyloside potassium salt is a powerful and specific inhibitor of mitochondrial ADP/ATP transport. Atractyloside potassium salt inhibits chloride channels from mitochondrial membranes of rat heart .

3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide	Terpenoids Pterocarpus soyauxii Taub. Sesquiterpenes Plants Compositae Source Classification	Others
3-Hydroxy-4,15-dinor-1(5)-xanthen-12,8-olide is a Sesquiterpenoids product that can be isolated from the roots of Xanthium sibiricum .

ent-16β,17-Dihydroxy-9(11)-kauren-19-oic acid	Terpenoids Pterocarpus soyauxii Taub. Diterpenoids Plants Compositae Source Classification	Others
ent-16β,17-Dihydroxy-9(11)-kauren-19-oic acid is a Diterpenoids product that can be isolated from the herbs of Xanthium sibiricum Patrin .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Xanthium sibiricum

Inhibitors & Agonists

NaturalProducts

Natural
Products