49 Results for "

acetyl groups

" in MedChemExpress (MCE) Product Catalog:
Products (49)

49 Results for "acetyl groups" in MCE Product Catalog:

10
10 Publications Verification
Art. -Nr.: HY-B1142
CAS. Nr.: 940-69-2
Synonyms: (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .
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7
7 Cited Publications
Art. -Nr.: HY-113596
CAS. Nr.: 102029-73-2
Reinheit:  99.22%
Synonyms: acetyl-CoA trisodium
Acetyl-coenzyme A (Acetyl-CoA) trisodium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trisodium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trisodium is also a key precursor of lipid synthesis .
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7
7 Cited Publications
Art. -Nr.: HY-113596A
CAS. Nr.: 32140-51-5
Reinheit:  97%
Synonyms: acetyl-CoA lithium
Acetyl-coenzyme A (Acetyl-CoA) lithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A lithium, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A lithium is also a key precursor of lipid synthesis .
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3
3 Cited Publications
Art. -Nr.: HY-136386
CAS. Nr.: 26117-28-2
Reinheit:  ≥97.0%
Forschungsgebiete:  

Others

N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
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1
1 Cited Publications
Art. -Nr.: HY-114365
CAS. Nr.: 108320-87-2
Reinheit:  99.95%
Synonyms: UDP-N-acetyl-D-galactosamine disodium
UDP-GalNAc (UDP-N-acetyl-D-galactosamine) disodium is a sugar nucleotide and a substrate for EpsC115. EpsC115 is a mutant with N-terminal residues 1-115 deleted from the exopolymeric substance (EPS). UDP-GalNAc disodium is a donor substrate for many N-acetylgalactosaminyltransferases, which transfer GalNAc from nucleotide sugars to sugar or peptide acceptors. UDP-GalNAc disodium provides a sugar group donor for glycosylation reactions. UDP-GalNAc disodium can be used in cancer research, such as colorectal and breast cancer .
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Art. -Nr.: HY-114293A
CAS. Nr.: 75520-41-1
Synonyms: acetyl-CoA trilithium
Acetyl-coenzyme A (Acetyl-CoA) trilithium is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A trilithium regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A trilithium is also a key precursor of lipid synthesis .
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Art. -Nr.: HY-114293
CAS. Nr.: 72-89-9
Synonyms: acetyl-CoA
Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis .
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Art. -Nr.: HY-134222A
CAS. Nr.: 16354-58-8
Reinheit:  ≥98.0%
Synonyms: N-acetyl-L-serine
N-Acetylserine (N-Acetyl-L-serine) is a complement pathway modulator targeting activated third complement protein (C3b) and an amino-terminal residue (an N-terminal acetylation modification group). N-Acetylserine reacts with the exposed thioester group of C3b via its hydroxyl group, thereby blocking the covalent binding of glycerol to this thioester group. N-Acetylserine widely exists in soluble proteins of mammalian cells (accounting for approximately 80% of such proteins). N-Acetylserine has a blocking property that prevents direct Edman sequencing of proteins; deblocking is achievable through trifluoroacetic acid-catalyzed N→O acetyl migration followed by β-elimination. N-Acetylserine is suitable for sequencing of proteins with N-terminal acetylserine modification .
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Art. -Nr.: HY-P10069
CAS. Nr.: 2313534-24-4
Forschungsgebiete:  

Others

Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide .
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Art. -Nr.: HY-D2869
CAS. Nr.: 2897614-60-5
Ac-H-FluNox is an acetylated cell-compatible prodrug of H-FluNox (HY-D2339). Ac-H-FluNox undergoes intracellular hydrolysis of its acetyl group by esterases to generate H-FluNox, which then undergoes a deoxygenation reaction with labile heme to form a fluorescent product. Ac-H-FluNox detects fluctuations of labile heme in living cells, acute labile heme release upon nitric oxide stimulation, and accumulation of labile heme following inhibition of heme export proteins .
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Art. -Nr.: HY-114293S
Reinheit:  97.40%
Synonyms: acetyl-CoA-13C2 lithium
Acetyl coenzyme A- 13C2 lithium is the 13C-labeled Acetyl coenzyme A (HY-114293). Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis .
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Art. -Nr.: HY-Y1080
CAS. Nr.: 19764-30-8
Synonyms: N-acetyl-D-leucine
N-Acetyl-R-leucine is an amino-protecting group N-substituted chiral amino acid. N-Acetyl-R-leucine is a PepT1 and MCT1 inhibitor with IC50 of 0.74 and 11 mM, respectively. N-Acetyl-R-leucine can be used for LysoTracker signaling studies .
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Art. -Nr.: HY-128852
CAS. Nr.: 14215-68-0
Reinheit:  ≥98.0%
N-Acetyl-D-galactosamine (GalNAc) is a terminal essential amino sugar derived from galactose and forms the antigens of blood group A in humans. N-Acetyl-D-galactosamine (GalNAc) interact with Soya bean agglutinin (SBA), hence decreasing the effects of SBA on cellular membrane permeability and tight junction protein expression in piglets . N-Acetyl-D-galactosamine (GalNAc) inhibits the hemagglutinating activity by the lectin .
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Art. -Nr.: HY-147004
CAS. Nr.: 903886-95-3
Reinheit:  99.88%
Forschungsgebiete:  

Metabolic Disease

A-908292 is a potent and selective acetyl-CoA carboxylase 2 (ACC2) inhibitor, with an IC50 of 23 nM for human ACC2. A-908292 can be used for the research of fatty acid metabolism . A-908292 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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Art. -Nr.: HY-P3749
CAS. Nr.: 323577-36-2
Target:  

Fluorescent Dye

Forschungsgebiete:  

Others

Mca-(ala7,lys(dnp)9)-bradykinin is a sensitive fluorogenic substrate for ECE-1 (endothelin-converting enzyme-1). The incorporation of a (7-methoxycoumarin-4-yl)acetyl (Mca) fluorescent group and a 2,4-dinitrophenyl (Dnp) quenching group has resulted in a large fluorescence increase upon substrate cleavage .
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Art. -Nr.: HY-114293S5
CAS. Nr.: 121443-44-5
Synonyms: acetyl-CoA-d3
Acetyl coenzyme A-d3 (Acetyl-CoA-d3) is the deuterium labeled Acetyl coenzyme A (HY-114293). Acetyl-coenzyme A (Acetyl-CoA) is a membrane-impermeant central metabolic intermediate, participates in the TCA cycle and oxidative phosphorylation metabolism. Acetyl-coenzyme A, regulates various cellular mechanisms by providing (sole donor) acetyl groups to target amino acid residues for post-translational acetylation reactions of proteins. Acetyl Coenzyme A is also a key precursor of lipid synthesis .
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Art. -Nr.: HY-W039943
CAS. Nr.: 121584-52-9
Target:  

Molecular Glues

Forschungsgebiete:  

Cancer

Acetyl-cyclosporin A aldehyde is an acetylated Cyclosporin A (HY-B0579) derivative with a reducing aldehyde group. Cyclosporin A is a potent calmodulin inhibitor and cyclophilin binder that can target the nuclear translocation of NF-AT and cause mitochondrial damage.
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Art. -Nr.: HY-W012898
CAS. Nr.: 95-45-4
Synonyms: Biacetyl dioxime
Dimethylglyoxime (Biacetyl dioxime) belongs to the class of oximes and consists of two acetyl groups attached to a nitrogen atom, which in turn is attached to another nitrogen atom through a diimine bond. Dimethylglyoxime is a specific chelator of Ni that inhibits or slows the aggregation of Aβ peptides in vitro .
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Art. -Nr.: HY-W102456
CAS. Nr.: 122555-04-8
Synonyms: L-4-acetylphenylalanine
Forschungsgebiete:  

Others

H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces .
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Art. -Nr.: HY-21983
CAS. Nr.: 45214-52-6
Forschungsgebiete:  

Others

O-Acetyl-N-[(1,1-dimethylethoxy)carbonyl]-L-threonine is a compound containing both an amino group and a carboxyl group.
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