76 Results for "

allergens

" in MedChemExpress (MCE) Product Catalog:
Products (76)

76 Results for "allergens" in MCE Product Catalog:

7
Methyl paraben
Methyl paraben
0 Images
7 Publications Verification
Cat. No.: HY-N0349
CAS No.: 99-76-3
Synonyms: Methyl 4-hydroxybenzoate
Category:  

Tsuga dumosa Plants Endogenous metabolite Infection Monophenols Animals Pinaceae Phenols Cosmetic Research Disease Research Fields

Target:  

Environmental Pollutants Endogenous Metabolite Bacterial

Methyl Paraben is a standardized methyl paraben allergen isolated from Yunnan hemlock (Tsuga dumosa). Methyl Paraben is commonly used as a stable, non-volatile preservative. Methyl Paraben increases histamine release and cellular regulation of immunity, blocks sodium channels, and prevents ischemia-reperfusion injury .
4
FR900359
FR900359
0 Images
4 Cited Publications
Cat. No.: HY-117037
CAS No.: 107530-18-7
Purity:  99.90%
Category:  

Ardisia crenata Sims Ketones, Aldehydes, Acids Plants Myrsinaceae

Target:  

Apoptosis ERK

FR900359 is a depsipeptide selective inhibitor of Gαq/11/14 in mammalia, can inhibits ERK pathway. FR900359 suppresses the proliferation of melanoma cells and decreases of blood pressure. FR900359 also protected against airway hyperreactivity in murine models of allergen sensitization in Ovalbumin, low endotoxin (HY-W250978A)-induced sensitization model of asthma. FR900359 can be used for cancer and cardiovascular disease research .
2
ODN 1018
ODN 1018
0 Images
2 Cited Publications
Cat. No.: HY-150724
CAS No.: 937402-51-2
Synonyms: 1018 ISS
Target:  

Toll-like Receptor (TLR)

Research Areas:  

Inflammation/Immunology

ODN 1018 (1018 ISS) is a TLR9 agonist and immune modulator. ODN 1018 exhibits adjuvant activity and augments CD8+ T cell responses with LNP-encapsulated OVA peptides. ODN 1018 triggers sustained suppression of allergic airway inflammation. ODN 1018 can be used for the research of allergic asthma and systemic lupus erythematosus .
2
Rosin
Rosin
0 Images
2 Cited Publications
Cat. No.: HY-N0508
CAS No.: 85026-55-7
Category:  

Rhodiola rosea Linn. Simple Phenylpropanols Crassulaceae Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Rosin is a natural resin extracted from coniferous trees such as pine trees. Rosin is a frequent contact allergen which induces allergic contact dermatitis. Rosin can be used as emulsifiers, adhesives, and other chemical applications .
2
AZD5423
AZD5423
0 Images
2 Cited Publications
Cat. No.: HY-108243
CAS No.: 1034148-04-3
Purity:  99.85%
Target:  

Glucocorticoid Receptor

Research Areas:  

Inflammation/Immunology Endocrinology

AZD5423 is an inhaled, potent, selective, and non-steroidal glucocorticoid receptor (GR) modulator (SGRM) . AZD5423 effectively reduces allergen-induced responses in subjects with mild allergic asthma .
2
GSK2245035
GSK2245035
0 Images
2 Cited Publications
Cat. No.: HY-118250
CAS No.: 1207629-49-9
Purity:  99.85%
Target:  

Toll-like Receptor (TLR) IFNAR TNF Receptor

Research Areas:  

Inflammation/Immunology

GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for asthma .
1
GS-6201
GS-6201
0 Images
1 Cited Publications
Cat. No.: HY-10081
CAS No.: 752222-83-6
Purity:  98.47%
Synonyms: CVT-6883
Target:  

Adenosine Receptor

Research Areas:  

Inflammation/Immunology

GS-6201 (CVT-6883) is a selective adenosine A2B receptor antagonist. GS-6201 displays high affinity and selectivity for the human adenosine A2B receptors (Ki=22 nM) . GS-6201 reduces caspase-1 activity in the heart, and attenuates cardiac remodeling after acute myocardial infarction (AMI) in the mouse . GS-62013 attenuates the airway reactivity induced by NECA, AMP, or allergen in sensitized mice .
β-Lactoglobulin
β-Lactoglobulin
0 Images
Cat. No.: HY-NP008
CAS No.: 9045-23-2
β-Lactoglobulin, a major whey protein, is a small globular protein from the lipocalin family. β-Lactoglobulin is an important source of the essential and branched-chain amino acids (leucine, isoleucine, and valine). β-Lactoglobulin shows antioxidant properties, because it contains two disulfide bonds and one free thiol group. β-Lactoglobulin is a ligand transport agent. β-Lactoglobulin is one of the major allergens in milk and can be utilized in the research for developing safe hypoallergenic dairy products .
Horse Serum Albumin
Horse Serum Albumin
0 Images
Cat. No.: HY-NP002J
CAS No.: 9048-46-8
Horse Serum Albumin is an abundant, multifunctional mammalian plasma protein and transport molecule. Horse Serum Albumin acts as an allergen, exhibits high cross-reactivity with serum albumins from other mammals, and contains epitope regions recognizable by antibodies. Horse Serum Albumin binds a variety of metabolites, drugs, nutrients, metals and other molecules .
Vilobelimab
Vilobelimab
0 Images
Cat. No.: HY-P99520
CAS No.: 2250440-41-4
Synonyms: CaCP-29, IFX-1

Target:  

Complement System SARS-CoV

Research Areas:  

Infection Inflammation/Immunology

Vilobelimab (CaCP-29, IFX-1) is a monoclonal anti-C5a antibody to the allergen C5a, a pro-inflammatory complement division product that plays a central role in mediating organ dysfunction. Vilobelimab acts as a C5a inhibitor, inhibiting neutrophil activation, chemotaxis, and reducing inflammatory signalling, and may be used in studies related to sepsis, COVID-19, etc .
House Dust Mite Extract, from D.farinae
House Dust Mite Extract, from D.farinae
0 Images
Cat. No.: HY-NP159
House Dust Mite Extract, from D.farinae is a house dust mite allergen extract derived from Dermatophagoides farinae. House Dust Mite Extract, from D.farinae significantly increases the levels of cytokines (IL-4, IL-5, IL-6) in bronchoalveolar lavage fluid. House Dust Mite Extract, from D.farinae upregulates the overexpression of MUC5AC. House Dust Mite Extract, from D.farinae induces allergic asthma and pulmonary inflammation .
Porcine Serum Albumin
Porcine Serum Albumin
0 Images
Cat. No.: HY-NP002E
CAS No.: 9048-46-8
Porcine Serum Albumin is a serum albumin protein that contains a flexible C-terminal region. Porcine Serum Albumin can serve both as a pork allergen and as a biomarker for detecting pork .
Chitinase, Streptomyces griseus
Chitinase, Streptomyces griseus
0 Images
Cat. No.: HY-P2797A
CAS No.: 9001-06-3
Synonyms: AMCase, Streptomyces griseus
Target:  

Biochemical Assay Reagents

Research Areas:  

Others

Chitinase, Streptomyces griseus is a chitinase from Streptomyces griseus. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
Salicyl alcohol
Salicyl alcohol
0 Images
Cat. No.: HY-B1419
CAS No.: 90-01-7
Synonyms: 2-Hydroxybenzyl alcohol; Saligenin
Category:  

Microorganisms Monophenols Other Diseases Phenols Disease Research Fields

Target:  

Drug Intermediate Bacterial

Salicyl alcohol (2-Hydroxybenzyl alcohol; Saligenin) is a phenolic alcohol-type topical anesthetic and strong sensitizer with antiseptic, antibacterial and antipyretic activities. Salicyl alcohol serves as a precursor for salicin synthesis. Salicyl alcohol induces contact dermatitis and eczematous skin reactions, and is a well-known allergen identified in phenolic resins. Salicyl alcohol is isolated from the barks of European aspen (Populus tremula), rowan (Sorbus aucuparia) and willow (Salix spp.). Salicyl alcohol is used in studies related to allergic contact dermatitis .
Ecleralimab
Ecleralimab
0 Images
Cat. No.: HY-P99872
CAS No.: 2415207-91-7
Synonyms: CSJ-117; NVP-CSJ117

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Ecleralimab (CSJ-117; NVP-CSJ117) is a Fab-IgG1-λ2 antibody targeting the thymic stromal lymphopoietin (TSLP). Ecleralimab significantly attenuates allergen-induced airway responses and inflammation. Ecleralimab can be used for the study of inhaled asthma .
PF-03654746 Tosylate
PF-03654746 Tosylate
0 Images
Cat. No.: HY-11044
CAS No.: 1039399-17-1
Purity:  99.1%
Target:  

Histamine Receptor

Research Areas:  

Neurological Disease Metabolic Disease Inflammation/Immunology

PF-03654746 Tosylate is a potent, selective and brain-penetrant histamine H3 receptor antagonist. PF-03654746 Tosylate reduces allergen-induced nasal symptoms . PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD) .
Chitinase, Serratia marcescens
Chitinase, Serratia marcescens
0 Images
Cat. No.: HY-P2797
CAS No.: 9001-06-3
Synonyms: AMCase, Serratia marcescens
Target:  

Biochemical Assay Reagents

Research Areas:  

Metabolic Disease Inflammation/Immunology

Chitinase, Serratia marcescens is a chitinase from Serratia marcescens. Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
Lumiliximab
Lumiliximab
0 Images
Cat. No.: HY-P99303
CAS No.: 357613-86-6
Synonyms: Gomiliximab; IDEC-152; ST-152

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Lumiliximab (Anti-CD23 Recombinant Antibody) is an anti-CD23 monoclonal antibody that inhibits allergen-induced responses .
RO0270608
RO0270608
0 Images
Cat. No.: HY-138542
CAS No.: 220846-33-3
Purity:  98.80%
Target:  

Integrin

Research Areas:  

Inflammation/Immunology

RO0270608, the active metabolite of R411, is a dual alpha4beta1-alpha4beta7 (α4β1/α4β7) integrin antagonist. Antiinflammatory activity .
Chitinase
Chitinase
0 Images
Cat. No.: HY-P2797B
CAS No.: 9001-06-3
Target:  

Biochemical Assay Reagents

Research Areas:  

Inflammation/Immunology

Chitinase is a chitin-targeting enzyme with chitin hydrolysis activity. Chitinase inhibits chitin-induced innate type 2 inflammation in the lung. Chitinase augments chitin-free, allergen-induced Th2 inflammation. Chitinase mediates effector functions of IL-13 .
Assay Types