1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. PF-03654746 Tosylate

PF-03654746 Tosylate 

Cat. No.: HY-11044
Handling Instructions

PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD).

For research use only. We do not sell to patients.

PF-03654746 Tosylate Chemical Structure

PF-03654746 Tosylate Chemical Structure

CAS No. : 1039399-17-1

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1 mg USD 150 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

PF-03654746 Tosylate is a potent and selective histamine H3 receptor antagonist with high brain penetration. PF-03654746 Tosylate reduces allergen-induced nasal symptoms[1]. PF-03654746 Tosylate has potential for treatment of human cognitive disorders, improves cognitive efficacy and disease-modifying effects in Alzheimer's disease (AD)[2].

IC50 & Target

H3 receptor[1]

Molecular Weight

494.59

Formula

C₂₅H₃₂F₂N₂O₄S

CAS No.

1039399-17-1

SMILES

O=C([[email protected]]1C[[email protected]](C1)(F)C2=CC=C(CN3CCCC3)C(F)=C2)NCC.O=S(C4=CC=C(C)C=C4)(O)=O

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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PF-03654746 Tosylate
Cat. No.:
HY-11044
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