14 Results for "

anti-CTLA4

" in MedChemExpress (MCE) Product Catalog:
Products (14)

14 Results for "anti-CTLA4" in MCE Product Catalog:

Cat. No.: HY-P990042
CAS No.: 2226344-78-9
Synonyms: ONC-392; BNT 316

Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology Cancer

Gotistobart (ONC-392; BNT 316) is a humanized anti-CTLA-4 antibody with selective regulatory T cell depletion activity in the tumor microenvironment. Gotistobart can be used for the research of cancer, such as non-small cell lung cancer .
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Cat. No.: HY-P990048
CAS No.: 2750031-18-4
Synonyms: ADG126

Target:  

CTLA-4

Research Areas:  

Cancer

Muzastotug is a humanized immunoglobulin G1-kappa, anti-CTLA4 monoclonal antibody. Muzastotug is an immunostimulant and antineoplastic .
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Cat. No.: HY-P99709
CAS No.: 2118349-31-6
Synonyms: LY3300054

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology Cancer

Lodapolimab (LY3300054) is a fully human IgG1λ anti-PD-L1 monoclonal antibody, with an EC50 of 0.075 nM against hPD-L1 and an EC50 of 0.085 nM against cynomolgus monkey PD-L1. Lodapolimab induces naive T cell activation, enhances the T cell activation effect of anti-CTLA4 antibodies, promotes anti-tumor alloreactivity, regulates innate immune pathways, and induces characteristics of adaptive immune activation. Lodapolimab can be used in research related to high-grade serous ovarian cancer and other solid tumors .
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Cat. No.: HY-P990703
CAS No.: 2649372-91-6
Synonyms: HBM-4003

Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology

Porustobart (HBM-4003) is a fully human anti-CTLA-4 heavy chain only antibody (HCAb). Porustobart can significantly improve the depletion of regulatory T cells (Treg cells) with high CTLA-4 expression in tumor tissues by enhancing ADCC activity. Porustobart can be used for tumor research .
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Cat. No.: HY-P99354
CAS No.: 2329669-78-3
Synonyms: anti-Human CTLA4xLAG3; XmAb-22841; Pavunalimab

Target:  

LAG-3

Research Areas:  

Inflammation/Immunology Cancer

Bavunalimab (Anti-Human CTLA4xLAG3) is a bispecific human anti-CTLA-4/LAG-3 monoclonal antibody. Bavunalimab activates T cells in NSG mice. Bavunalimab can be used for the research of cancer .
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Cat. No.: HY-P990385

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-CTLA-4/CD152 Antibody is an anobody that targets CTLA-4/CD152. The Anti-CTLA-4/CD152 Antibody has a huIgG4SP type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 145 kDa. The isotype control for the Anti-CTLA-4/CD152 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990848

Target:  

CTLA-4

Research Areas:  

Infection Inflammation/Immunology

Anti-CTLA-4/CD152 Antibody (BN13) is a kind of mouse IgG2a κ chimeric antibody inhibitor, targeting to human CTLA-4/CD152. Anti-CTLA-4/CD152 Antibody (BN13) can neutralize CTLA-4 (cytotoxic T lymphocyte antigen-4) also known as CD152. Anti-CTLA-4/CD152 Antibody (BN13) can be used for the researches of infection and immunology, such as human immunodeficiency virus (HIV) .
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Cat. No.: HY-P990080
CAS No.: 2649371-19-5
Synonyms: BMS-986249

Target:  

CTLA-4

Research Areas:  

Cancer

Sovipostobart is an immunoglobulin G1-kappa, anti-CTLA-4 human monoclonal antibody with cleavable prodomain. Sovipostobart is an immunostimulant and antineoplastic .
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Cat. No.: HY-P990739
CAS No.: 2460399-39-5
Synonyms: BA-3071
Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology

Evalstotug is an anti-CTLA4 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990775
CAS No.: 2760549-50-4
Synonyms: XTX101

Target:  

CTLA-4

Research Areas:  

Inflammation/Immunology

Vilastobart is an anti-CTLA4 human IgG1 κ monoclonal antibody . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990722
CAS No.: 2599198-80-6

Target:  

PD-1/PD-L1

Research Areas:  

Inflammation/Immunology

Danvilostomig is an anti-CTLA4/PDCD1 monoclonal antibody .
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Cat. No.: HY-P991961

Target:  

CTLA-4

Research Areas:  

Cancer

REGN4659 is a fully human anti-CTLA-4 monoclonal antibody and IgG1 antibody. REGN4659 binds to the extracellular domain of human and monkey CTLA-4 with high affinity and specificity. REGN4659 blocks CTLA-4 interaction with CD80 and CD86 ligands. REGN4659 significantly suppresses MC38.Ova tumor growth in CTLA-4 knock-in mice .
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Cat. No.: HY-120120
CAS No.: 1403850-91-8
Target:  

Microtubule/Tubulin

Research Areas:  

Cancer

DZ-2384 is a potent microtubule-targeting agent. DZ-2384 increases the rescue frequency and preserves the microtubule network in nonmitotic cells and primary neurons. DZ-2384 acts synergistically with anti-CTLA-4 immunotherapy in Taxane-sensitive and Taxane-resistant xenograft murine models of triple-negative breast cancer (TNBC). DZ-2384 exhibits potent antitumor activity in adult acute lymphocytic leukemia (ALL) models. DZ-2384 can be used for cancer research, such as TNBC and ALL [1][2].
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Cat. No.: HY-P991958

Target:  

CTLA-4

Research Areas:  

Cancer

GIGA-564 is a fully human anti-CTLA4 IgG1 monoclonal antibody with a Kd of 9.8 nM. GIGA-564 binds to a unique epitope of CTLA-4, mediates FcR-dependent signaling pathways, depletes CTLA-4-highly-expressing regulatory T cells within tumors, and inhibits the proliferation of peripheral regulatory T cells. GIGA-564 exhibits anti-tumor activity in mouse models. GIGA-564 can be used for tumor research .
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