8 Results for "

aryl hydrocarbon hydroxylase

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "aryl hydrocarbon hydroxylase" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W017113
CAS No.: 149-30-4
2-Mercaptobenzothiazole is an activator of the aryl hydrocarbon receptor (AhR) , inhibiting thyroid hormone synthesis and dopamine beta-hydroxylase activity . 2-Mercaptobenzothiazole promotes bladder cancer cell invasion by altering the conformation of the AhR ligand binding domain (LBD), activating AhR transcription, and upregulating the mRNA and protein expression of target genes CYP1A1 and CYP1B1 . 2-Mercaptobenzothiazole inhibits thyroid peroxidase (TPO) with an IC50 value of 11.5 μM, induces histological changes such as follicular cell hypertrophy in Xenopus laevis tadpoles, delaying metamorphosis . 2-Mercaptobenzothiazole increases chromosomal aberrations and sister chromatid exchanges (SCEs) in Chinese hamster ovary (CHO) cells, and enhances carcinogenicity in F344/N rats . 2-Mercaptobenzothiazole inhibits norepinephrine synthesis in mice and completely blocks the conversion of exogenous dopamine to norepinephrine in rat cardiomyocytes .
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Cat. No.: HY-W014018
CAS No.: 92-71-7
Synonyms: PPO; DPO; POP
2,5-Diphenyloxazole (PPO; DPO; POP) is a fluorescent dye, as well as a substrate and metabolite precursor of cytochrome P-450 (cytochrome P-448/P1-450). 2,5-Diphenyloxazole serves as a scintillator .
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Cat. No.: HY-W762018
CAS No.: 60851-34-5
Synonyms: 2,3,4,6,7,8-HxCDF
Target:  

Cytochrome P450

Research Areas:  

Infection Cancer

2,3,4,6,7,8-Hexachlorodibenzofuran (2,3,4,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 2,3,4,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 0.687 and 0.575 nM, respectively) .
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Cat. No.: HY-W517092
CAS No.: 55673-89-7
Synonyms: 1,2,3,4,7,8,9-HpCDF
1,2,3,4,7,8,9-Heptachlorodibenzofuran (1,2,3,4,7,8,9-HpCDF) is a compound that induces the expression of CYP1A1 and CYP1B1 genes in human peripheral blood lymphocytes, while also promoting the expression of the aryl hydrocarbon receptor repressor (AhRR). 1,2,3,4,7,8,9-Heptachlorodibenzofuran can increase ethoxyresorufin-O-deethylase (EROD) activity in isolated human peripheral blood lymphocytes in a concentration-dependent manner, which serves as a marker of CYP1A1 activity. Furthermore, 1,2,3,4,7,8,9-Heptachlorodibenzofuran exhibits immunosuppressive effects by reducing the number of splenic plaque-forming cells in mice and increasing aryl hydrocarbon hydroxylase (AHH) activity in liver microsomes of mice injected with sheep red blood cells. 1,2,3,4,7,8,9-Heptachlorodibenzofuran can be used in research in the fields of immunology, metabolic diseases, and environmental toxicology .
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Cat. No.: HY-W762015
CAS No.: 57117-44-9
Synonyms: 1,2,3,6,7,8-HxCDF
Target:  

Cytochrome P450

Research Areas:  

Cancer

1,2,3,6,7,8-Hexachlorodibenzofuran (1,2,3,6,7,8-HxCDF) is a dioxin-like polychlorinated dibenzofuran (PCDF). 1,2,3,6,7,8-Hexachlorodibenzofuran induces expression of the genes encoding aryl hydrocarbon hydroxylase (AHH) and ethoxyresorufin-O-deethylase (EROD) in H-4-II-E rat hepatoma cells (EC50s = 1.47 and 1.24 nM, respectively). 1,2,3,6,7,8-Hexachlorodibenzofuran reduces weight, induces thymic atrophy, and induces the expression of genes encoding the cytochrome P450 (CYP) isoform CYP1A1 and 4-chlorobiphenyl hydroxylase in rats (EC50s = 3.2, 0.9, 0.35, and 0.21 µmol/kg, respectively) .
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Cat. No.: HY-P81245
Synonyms: Cytochrome P450 1A2; cytochrome P450, family 1, subfamily a, polypeptide 2; Cytochrome P450 family 1 polypeptide 2; Cytochrome P450 subfamily I aromatic compound inducible polypeptide 2; Cyp1a2; CYPD45; P-450d; RATCYPD45; CP12; CP 12; P3-450; aryl hydrocarbon hydroxylase; Dioxin inducable P3 45; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 4; P450 form 4; P450 P3; P450(PA); Xenobiotic monooxygenase; P450 1A2.

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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Cat. No.: HY-184854
CAS No.: 92341-07-6
Target:  

Drug Derivative

Research Areas:  

Others

1,2,3,4,8,9-Hexachlorodibenzofuran is a polychlorinated dibenzofuran (PCDF) congener with chlorine substitutions at positions 1,2,3,4,8,9 .
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Cat. No.: HY-P705910
Purity:  ≥ 90%, as determined by reducing SDS-PAGE .
Synonyms: CYP3A5; Flavoprotein-Linked Monooxygenase; Cytochrome P450 Family 3 Subfamily A Member 5; aryl hydrocarbon hydroxylase; P450PCN3; Alternative Protein CYP3A5; CP35; Microsomal Monooxygenase; PCN3; Xenobiotic Monooxygenase; Cytochrome P450, Subfamily IIIA (Niphedipine Oxidase), Polypeptide 5; Unspecific Monooxygenase; Cytochrome P450, Family 3, Subfamily A, Polypeptide 5; Cytochrome P450 HLp2; Cytochrome P450-PCN3; Cytochrome P450 3A; Cytochrome P450 3A5; Cytochrome P-450; CYPIIIA5; DKFZp686I18188; Uncharacterized Protein DKFZp686I18188
Species:  
Human
Source:  
E. coli
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