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bicyclic monoterpene

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By Targets:	Bacterial (1) COX (3) Cytochrome P450 (1) Drug Isomer (1) Endogenous Metabolite (1) Environmental Pollutants (1) Reference Standards (2)
By Research Areas:	Infection (1) Inflammation/Immunology (3)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-108943

Sabinene 2 Publications Verification	Others	Others
Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways .

HY-N5132

(-)-Fenchone	Cytochrome P450	Others
(-)-Fenchone is a bicyclic monoterpene and serves as a substrate for human liver microsomal cytochrome P450 enzymes CYP2A6 and CYP2B6. (-)-Fenchone is not metabolized by human CYP1A1, CYP1A2, CYP1B1, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, or CYP3A4 enzymes. (-)-Fenchone undergoes hydroxylation to produce 6-exo-hydroxyfenchone, 6-endo-hydroxyfenchone, and 10-hydroxyfenchone. During the metabolism of (-)-Fenchone, CYP2A6 may play a more important role than CYP2B6 .

HY-N6663

3-Carene	Environmental Pollutants COX	Inflammation/Immunology
3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

HY-126027

(+)-3-Carene	Drug Isomer COX	Inflammation/Immunology
(+)-3-Carene, a bicyclic monoterpene, is one of the major components of the pine tree essential oils. (+)-3-Carene is a (+)-enantiomer of 3-Carene (HY-N6663) .

HY-W588249

Sabinene hydrate	Bacterial Endogenous Metabolite	Infection
Sabinene hydrate is a volatile organic compound of a bicyclic monoterpene alcohol. Sabinene hydrate, as a plant secondary metabolite, is naturally present in various plants and their essential oils. Sabinene hydrate exhibits broad-spectrum but varying-intensity antibacterial activity, with the greatest sensitivity to Gram-positive bacteria, especially Bacillus subtilis (MIC = 0.0312 mg/mL) and Staphylococcus aureus (MIC = 0.0625 mg/mL). Sabinene hydrate also shows certain sensitivity to Escherichia coli and Candida albicans, with MIC values of 0.125 mg/mL for both. Sabinene hydrate can be used in the research of the ecological functions of plant defense substances .

HY-W718719

Tricyclene	Others	Others
Tricyclene is a natural bicyclic monoterpene hydrocarbon, and it is one of the main components in the essential oil of Salvia aegyptiaca L .

HY-N6663R

3-Carene (Standard)	Reference Standards COX	Inflammation/Immunology
3-Carene (Standard) is the analytical standard of 3-Carene. This product is intended for research and analytical applications. 3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

HY-N5132R

(-)-Fenchone (Standard)	Reference Standards Others	Others
(-)-Fenchone (Standard) is the analytical standard of (-)-Fenchone. This product is intended for research and analytical applications. (-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Foeniculum vulgare. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6 .

Sabinene 2 Publications Verification	Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Other Diseases Plants Disease Research Fields Source Classification	Others
Sabinene is an naturally occurring bicyclic monoterpene which can be used as flavorings, perfume additives, fine chemicals, and advanced biofuels. Sabinene is also an orally active compound to attenuates skeletal muscle atrophy and regulates ROS-mediated MAPK/MuRF-1 pathways .

(-)-Fenchone	Structural Classification Other Monoterpenes Classification of Application Fields Terpenoids Other Diseases Umbelliferae Plants Vernonia Schreb. Disease Research Fields Source Classification	Cytochrome P450
(-)-Fenchone is a bicyclic monoterpene and serves as a substrate for human liver microsomal cytochrome P450 enzymes CYP2A6 and CYP2B6. (-)-Fenchone is not metabolized by human CYP1A1, CYP1A2, CYP1B1, CYP2C8, CYP2C9, CYP2C19, CYP2D6, CYP2E1, or CYP3A4 enzymes. (-)-Fenchone undergoes hydroxylation to produce 6-exo-hydroxyfenchone, 6-endo-hydroxyfenchone, and 10-hydroxyfenchone. During the metabolism of (-)-Fenchone, CYP2A6 may play a more important role than CYP2B6 .

3-Carene	Structural Classification Other Monoterpenes other families Classification of Application Fields Terpenoids Plants Inflammation/Immunology Disease Research Fields Source Classification	Environmental Pollutants COX
3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

(+)-3-Carene	Structural Classification Other Monoterpenes Classification of Application Fields Pinaceae Terpenoids Plants Pinus massoniana Lamb. Inflammation/Immunology Disease Research Fields Source Classification	Drug Isomer COX
(+)-3-Carene, a bicyclic monoterpene, is one of the major components of the pine tree essential oils. (+)-3-Carene is a (+)-enantiomer of 3-Carene (HY-N6663) .

Sabinene hydrate	Structural Classification Other Monoterpenes Juniperus communis L. Cupressaceae Terpenoids Plants Source Classification	Bacterial Endogenous Metabolite
Sabinene hydrate is a volatile organic compound of a bicyclic monoterpene alcohol. Sabinene hydrate, as a plant secondary metabolite, is naturally present in various plants and their essential oils. Sabinene hydrate exhibits broad-spectrum but varying-intensity antibacterial activity, with the greatest sensitivity to Gram-positive bacteria, especially Bacillus subtilis (MIC = 0.0312 mg/mL) and Staphylococcus aureus (MIC = 0.0625 mg/mL). Sabinene hydrate also shows certain sensitivity to Escherichia coli and Candida albicans, with MIC values of 0.125 mg/mL for both. Sabinene hydrate can be used in the research of the ecological functions of plant defense substances .

Tricyclene	Structural Classification Terpenoids Labiatae Sesquiterpenes Pteris semipinnata L. Sp. Plants Source Classification	Others
Tricyclene is a natural bicyclic monoterpene hydrocarbon, and it is one of the main components in the essential oil of Salvia aegyptiaca L .

3-Carene (Standard)	Structural Classification Other Monoterpenes other families Terpenoids Plants Source Classification	Reference Standards COX
3-Carene (Standard) is the analytical standard of 3-Carene. This product is intended for research and analytical applications. 3-Carene is a bicyclic monoterpene in essential oils extracted from pine trees. 3-Carene inhibits nociceptive stimulus-induced inflammatory infiltrates and COX-2 overexpression, and with antinociceptive effect. 3-Carene stimulates the activity and expression of alkaline phosphatase that is an early phase marker of osteoblastic differentiation .

(-)-Fenchone (Standard)	Structural Classification Other Monoterpenes Terpenoids Umbelliferae Plants Vernonia Schreb. Source Classification	Reference Standards Others
(-)-Fenchone (Standard) is the analytical standard of (-)-Fenchone. This product is intended for research and analytical applications. (-)-Fenchone, a bicyclic monoterpene, is widely distributed in plants and found in essential oils from Foeniculum vulgare. (-)-Fenchone is oxidized to 6-endo-hydroxyfenchone, 6-exo-hydroxyfenchone and 10-hydroxyfenchone derivatives by CYP2A6 and CYP2B6 in human liver microsomes with CYP2A6 playing a more important role than CYP2B6 .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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bicyclic monoterpene

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