2 Results for "

c-Myc inhibitor 10

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "c-Myc inhibitor 10" in MCE Product Catalog:

Cat. No.: HY-154839
CAS No.: 2299227-75-9
Target:  

c-Myc

Research Areas:  

Cancer

c-Myc inhibitor 10 (compound 17), a c-Myc inhibitor, exhibits increased cellular potency, consistent with an increase in permeability with methylation of the morpholine nitrogen .
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Cat. No.: HY-162460
CAS No.: 3056077-07-4
Target:  

ERK

Research Areas:  

Cancer

ERK1/2 inhibitor 10 (Compound 36c) is a potent ERK1 and ERK2 inhibitor (IC50: 0.11 and 0.08 nM respectively). ERK1/2 inhibitor 10 inhibits ERK1/2 and blocks the phosphorylation expression of their downstream substrates p90RSK and c-Myc. ERK1/2 inhibitor 10 induces cell apoptosis and incomplete autophagy-related cell death. ERK1/2 inhibitor 10 shows potent antitumor efficacy against triple-negative breast cancer and colorectal cancer models harboring BRAF and RAS mutations .
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