26 Results for "

chitin synthase

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "chitin synthase" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-19593
CAS No.: 59456-70-1
Target:  

Fungal

Research Areas:  

Infection

Nikkomycin Z is a nucleoside peptide and an orally active antifungal agent. Nikkomycin Z inhibits chitin synthesis by acting as a competitive analogue of the chitin synthase substrate UDP-N-acetylglucosamine. Nikkomycin Z has antifungal activity .
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Cat. No.: HY-178175
Target:  

Insecticide

Research Areas:  

Infection

Chitin synthase-IN-15 (Compound 6k) is a chitin synthase inhibitor. Chitin synthase-IN-15 has insecticidal efficacy against Plutella xylostella, with LC50 values of 0.789 and 0.951 μg/mL. Chitin synthase-IN-15 induces molting disruptions, larval mortality, and aberrant pupation, thereby effectively mitigating pest populations. Chitin synthase-IN-15 is an insecticidal agent with favorable ecological safety profiles .
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Cat. No.: HY-150584
CAS No.: 2416338-26-4
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 3 (compound 2d) is a potent chitin synthase inhibitor with an IC50 value of 0.16 mM, and MIC of 1 µg/mL against candida albicans. Antifungal activity .
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Cat. No.: HY-150583
CAS No.: 2416338-24-2
Target:  

Fungal

Research Areas:  

Inflammation/Immunology

Chitin synthase inhibitor 2 (compound 2b) is a potent inhibitor of chitin synthase with the IC50 value of 0.09 mM and the Ki value of 0.12 mM. Chitin synthase inhibitor 2 has antimicrobial activities in vitro and shows synergistic or additive effects with fluconazole or polyoxin B .
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Cat. No.: HY-N14827
CAS No.: 151466-15-8
Synonyms: SM-216289
Target:  

Drug Derivative

Xanthofulvin (SM-216289) is an inhibitor of semaphorin 3A. Xanthofulvin blocks its binding to receptors, inhibits growth cone collapse, and accelerates olfactory nerve regeneration in rats in vivo. Xanthofulvin can be used in studies related to traumatic neuronal injury .
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Cat. No.: HY-150686
CAS No.: 2755847-31-3
Purity:  99.48%
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 4 (compound 4fh) is a chitin synthase inhibitor with fungicidal effect. Chitin synthase inhibitor 4 is a potential chitin synthase-based fungicide in agriculture .
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Cat. No.: HY-144391
CAS No.: 2763387-69-3
Target:  

Fungal

Research Areas:  

Inflammation/Immunology

Chitin synthase inhibitor 1 is a potent and selective chitin synthase (CHS) inhibitor (IC50=0.12 mM). Chitin synthase inhibitor 1 has potent antifungal activity against drug-resistant fungi variants .
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Cat. No.: HY-151418
CAS No.: 3033645-31-4
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal activity. Chitin synthase inhibitor 8 can be used in the research of fungi infection .
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Cat. No.: HY-151419
CAS No.: 2725074-96-2
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal activity. Chitin synthase inhibitor 9 can be used in the research of fungi infection .
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Cat. No.: HY-151416
CAS No.: 3033645-29-0
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 6 (compound 9b) is a potent chitin synthase (CHS) inhibitor with an IC50 value of 0.21 mM. Chitin synthase inhibitor 6 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 6 can be used in the research of fungi infection .
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Cat. No.: HY-151417
CAS No.: 3033645-30-3
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 7 (compound 9c) is a potent chitin synthase (CHS) inhibitor with an IC50 value of 0.37 mM. Chitin synthase inhibitor 7 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 7 can be used in the research of fungi infection .
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Cat. No.: HY-149585
CAS No.: 2922114-19-8
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 14 (compound 4n) is chitin synthase (CHS) inhibitor. Chitin synthase inhibitor 14 has antifungal activity while possessed the potency against drug-resistant fungal variants .
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Cat. No.: HY-151421
CAS No.: 2725075-04-5
Target:  

Fungal

Research Areas:  

Infection Cancer

Chitin synthase inhibitor 11 is a chitin synthase inhibitor. Chitin synthase inhibitor 11 shows excellent chitin synthase inhibitory activity with an IC50 value of 0.10 mM. Chitin synthase inhibitor 11 has broad-spectrum antifungal activity in vitro. Chitin synthase inhibitor 11 can be used for the research of invasive fungal infections (IFIs) .
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Cat. No.: HY-151420
CAS No.: 2725075-01-2
Target:  

Fungal

Research Areas:  

Infection Cancer

Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC50 value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs) .
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Cat. No.: HY-151422
CAS No.: 2725075-05-6
Target:  

Fungal

Research Areas:  

Infection Cancer

Chitin synthase inhibitor 12 is a chitin synthase inhibitor. Chitin synthase inhibitor 12 shows excellent inhibitory activity with an IC50 value of 0.16 mM. Chitin synthase inhibitor 12 also is a broad-spectrum antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 12 can be used for the research of invasive fungal infections (IFIs) .
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Cat. No.: HY-155569
CAS No.: 2925228-79-9
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 13 (compound 12g) is a non-competitive inhibitor of chitin synthase, with an IC50 of 106.7 μM. Chitin synthase inhibitor 13 exhibits a broad-spectrum of antifungal activity .
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Cat. No.: HY-151410
CAS No.: 3033645-28-9
Target:  

Fungal

Research Areas:  

Infection

Chitin synthase inhibitor 5 (compound 9a) is an inhibitor of chitin synthase with an IC50 value of 0.14 mM. Chitin synthase inhibitor 5 shows broad-spectrum antifungal activity in vitro and shows good inhibition to C. albicans, A. flavus, A. fumigatus and C. neoformans. Chitin synthase inhibitor 5 can be used for the research of fungal .
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Cat. No.: HY-125916
CAS No.: 58523-30-1
Pseurotin A is a secondary metabolite of Aspergillus and other fungi. Pseurotin A is a competitive inhibitor of chitin synthase and a neuritogenic agent. Pseurotin A inhibits IgE production (IC50 = 3.6 μM). Pseurotin A inhibits the PCSK9-LDLr interaction. Pseurotin A shows dose-dependent reduction of PCSK9, along with increased LDLR levels in hormone-dependent breast cancer cell lines. Pseurotin A exhibits antitumor activity .
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Cat. No.: HY-B1838A
CAS No.: 14089-43-1
Target:  

Fungal

Research Areas:  

Infection

Asulam (potassium salt) is a chitin synthase inhibitor against plant pathogenic fungi. Asulam (potassium salt) interferes with the biosynthesis of chitin in the fungal cell wall to destroy the integrity and normal growth and reproduction of fungal cells, thereby exerting bacteriostatic activity. Asulam (potassium salt) is promising for research of fungal diseases such as downy mildew and gray mold in spinach, tulips, daffodils and lilies .
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Cat. No.: HY-N8512
CAS No.: 129277-10-7
Asperfuran is an antifungal dihydrobenzofuran derivative produced by a strain of Aspergillus oryzae. Asperfuran weakly inhibits chitin synthase from Coprinus cinereus. Asperfuran shows weak cytotoxicity In HeLa S3 and L1210 cells with an IC50 of 25 μg/ml .
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