2725075-01-2
Chemical Structure
Chitin synthase inhibitor 10
- CAS No.: 2725075-01-2
- Formula:C24H23Br2N3O6
- Molecular Weight:609.26
IUPAC Name: (E)-N-(2,6-dibromo-4-methoxyphenyl)-4-(6-methoxy-2-oxo-1,2-dihydrospiro[benzo[d][1,3]oxazine-4,4'-piperidin]-1'-yl)-4-oxobut-2-enamide
InChIKey: DTCGATPUSSPYTQ-AATRIKPKSA-N
SMILES: O=C(NC1=C(Br)C=C(OC)C=C1Br)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O
Biological Activity: Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC50 value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs)[1].
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Chitin synthase inhibitor 10 | Chitin synthase inhibitor 10 is a chitin synthase inhibitor. Chitin synthase inhibitor 10 shows excellent chitin synthase inhibitory activity with an IC50 value of 0.11 mM. Chitin synthase inhibitor 10 also is an antifungal agent and has significantly antifungal activity against drug-resistant fungal variants, such as C. albicans and C. neoformans. Chitin synthase inhibitor 10 can be used for the research of invasive fungal infections (IFIs). | |||||||||||||||||||||
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Keywords
