Chitin synthase inhibitor 7
Chitin synthase inhibitor 7 (compound 9c) is a potent chitin synthase (CHS) inhibitor with an IC50 value of 0.37 mM. Chitin synthase inhibitor 7 has broad-spectrum antifungal activity against drug-resistant fungi. Chitin synthase inhibitor 7 can be used in the research of fungi infection.
For research use only. We do not sell to patients.
- CAS No.: 3033645-30-3
- Formula: C24H25N3O5
- Molecular Weight:435.47
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chitin synthase inhibitor 7 (compound 9c; 300 μg/mL) inhibits chitin synthase (CHS) activity with an inhibition percentage (IP) value of nearly 70% [1].
Chitin synthase inhibitor 7 (1-512 μg/mL) has antifungal activity against four strains with minimum inhibitory concentration (MIC) values of 128, 256, 256, and 256 μg/mL for C. albicans, A. flavus, A. fumigatus, and C. neoformans, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3033645-30-3
-
Molecular Weight 435.47
-
Formula C24H25N3O5
-
SMILES
O=C(NC1=CC=C(C)C=C1)/C=C/C(N2CCC3(CC2)C4=CC(OC)=CC=C4NC(O3)=O)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)