3 Results for "

cholangiocarcinoma HepG2

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "cholangiocarcinoma HepG2" in MCE Product Catalog:

Cat. No.: HY-149486
Target:  

FGFR

Research Areas:  

Cancer

FGFR1 inhibitor 7 (compound 5) is an inhibitor of FGFR1 Tyrosine Kinase with IC50 value of 0.33 nM. FGFR1 inhibitor 7 shows broad-spectrum cytotoxicity agasinst human cancer cell lines, and inhibits MOLT3 cells with IC50 of 2.1 μM .
loading...
    loading...
Cat. No.: HY-180324
CAS No.: 77727-18-5
Candidone is a type of flavanone phenolic compound with anti-cancer and antibacterial activities. Candidone inhibits the proliferation of hepatoblastoma and cholangiocarcinoma cells and induces their apoptosis by up-regulating p21, Bax, and caspase 3/9, and down-regulating Bcl-2 and survivin. It reduces the metastatic ability of cancer cells by inhibiting the expression of phosphorylated p38 and matrix metalloproteinase MMP-9. Candidone has inhibitory effects on multidrug-resistant bacterial strains. Candidone binds to the base pairs of DNA in a groove-binding manner, thereby slightly altering the conformation of DNA .
loading...
    loading...
Cat. No.: HY-N19127
CAS No.: 1454586-51-6
Aspergillusidone E is an aromatase inhibitor with an aromatase IC50 of 1.0 μM. Aspergillusidone E exhibits cytotoxicity against cancer cells. Aspergillusidone E can be used in research related to various cancers such as breast cancer and liver cancer .
loading...
    loading...