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Results for "

chromogenic

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (1) Angiotensin-converting Enzyme (ACE) (2) Antibiotic (2) Antibody-Drug Conjugates (ADCs) (13) APC (2) Apoptosis (2) Bacterial (3) Beta-lactamase (2) Biochemical Assay Reagents (66) Caspase (6) Cathepsin (2) CD2 (1) Cholinesterase (ChE) (3) COX (1) Cytochrome P450 (3) Dengue Virus (1) Dipeptidyl Peptidase (1) DNA Stain (1) Drug-Linker Conjugates for ADC (3) EGFR (5) Elastase (1) Endogenous Metabolite (6) Environmental Pollutants (1) Factor VIII (1) Factor Xa (7) Factor XI (3) Flavivirus (1) Fluorescent Dye (87) Glycosidase (6) GSK-3 (1) HCV Protease (1) HIV Protease (1) Interleukin Related (1) Isotope-Labeled Compounds (2) Kallikrein (2) Lipase (3) Microtubule/Tubulin (1) MMP (3) MOFs (1) Mucin (1) Nectin-4 (2) NF-κB (1) NO Synthase (1) PAI-1 (2) Parasite (1) Phosphatase (6) Phosphodiesterase (PDE) (1) Phospholipase (2) Plasminogen/Plasmin (2) Poly(ADP-ribose) Glycohydrolase (PARG) (1) Protease Activated Receptor (PAR) (1) Reactive Oxygen Species (ROS) (7) Reference Standards (5) SARS-CoV (1) Ser/Thr Protease (13) Thrombin (6) Topoisomerase (4) Transmembrane Glycoprotein (2) β-catenin (1) β-glucuronidase (3)
By Research Areas:	Cancer (27) Cardiovascular Disease (9) Endocrinology (1) Infection (11) Inflammation/Immunology (5) Metabolic Disease (16) Neurological Disease (3)
Oligonucleotides:	Guanosine (1) Nucleoside Analogs (1)

236

Inhibitors & Agonists

115

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-15934

X-GAL 5 Publications Verification BCIG	Fluorescent Dye Glycosidase	Others
X-GAL (BCIG) is a widely used chromogenic β-galactosidase substrate. X-GAL is a colorless compound until cleaved by β-galactosidase, at which point X-GAL turns to an insoluble and detectable blue compound, making X-GAL particularly useful in techniques such as blue-white screening for cloning in bacteria. X-GAL can also be used for detection of β-galactosidase activity .

HY-D0908

Ninhydrin	Fluorescent Dye	Others
Ninhydrin can be used as a chromogenic analytical probe for the quantification of amino acids and proteins.

HY-108913

Nitrocefin 2 Publications Verification	Beta-lactamase Antibiotic Bacterial	Infection
Nitrocefin is a highly activated, chromogenic cephalosporin derivative. Nitrocefin is a chromogenic β-lactamase substrate. Nitrocefin undergoes a distinctive color change from yellow to red as the amide bond in the β-lactam ring is hydrolyzed by β-lactamase. Nitrocefin is used in competitive inhibition studies in developmental work on β-lactamase-resistant antibiotics .

HY-15928

4-Nitrophenyl phosphate disodium 1 Publications Verification p-Nitrophenyl phosphate disodium	Fluorescent Dye	Others
4-Nitrophenyl phosphate (p-Nitrophenyl phosphate) disodium is a non-proteinaceous chromogenic substrate for alkaline and acid phosphatases used in ELISA and conventional spectrophotometric assays.

HY-15930

TMB 5+ Cited Publications BM blue; Sure Blue TMB	Fluorescent Dye MOFs Reactive Oxygen Species (ROS)	Others
TMB is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-137276

5-Bromo-3-indolyl β-D-galactopyranoside Bluo-Gal	Fluorescent Dye Glycosidase	Others
5-Bromo-3-indolyl β-D-galactopyranoside (Bluo-Gal) is a chromogenic substrate for β-galactosidase. 5-Bromo-3-indolyl β-D-galactopyranoside is hydrolyzed by the enzyme to generate a 5-bromoindole intermediate, which is further oxidized to form an insoluble blue precipitate. 5-Bromo-3-indolyl β-D-galactopyranoside can specifically recognize bacterial β-galactosidases (such as the product of the Escherichia coli lacZ gene) and reacts at pH 7.4, making it suitable for light and electron microscopic observations. 5-Bromo-3-indolyl β-D-galactopyranoside can be used in histochemical detection of reporter gene expression in transgenic organisms, such as the localization analysis of β-galactosidase activity in mouse embryos or muscle tissues .

HY-D0995

7-Methyl-6-thioguanosine 2 Publications Verification MESG	Fluorescent Dye	Others
7-Methyl-6-thioguanosine (MESG) is a chromogenic substrate that can be converted to 7-methyl-6-thioguanine in the presence of purine nucleoside phosphorylase and inorganic phosphate. 7-Methyl-6-thioguanosine can be used to quantify inorganic phosphate. 7-Methyl-6-thioguanosine can also be used to determine the activities of purine nucleoside phosphorylase and protein phosphatases .

HY-Y0015

p-Dimethylaminobenzaldehyde 4-Dimethylaminobenzaldehyde	Biochemical Assay Reagents	Others
p-Dimethylaminobenzaldehyde (4-Dimethylaminobenzaldehyde) can be used as a chromogenic reagent or as an absorbent agent for heavy metal ions .

HY-119244

Gly-Pro-pNA hydrochloride	Dipeptidyl Peptidase	Metabolic Disease
Gly-Pro-pNA hydrochloride is a chromogenic peptide substrate that can be cleaved by the circulating enzyme dipeptidyl peptidase IV (DPP IV). Gly-Pro-pNA hydrochloride is mainly used to detect the activity of aminopeptidases such as DPP IV. Gly-Pro-pNA hydrochloride can be investigated as an experimental antidiabetic agent .

HY-P2685

MeOSuc-Ala-Ala-Pro-Val-pNA	Fluorescent Dye	Others
MeOSuc-Ala-Ala-Pro-Val-pNA is a sensitive chromogenic substrate for human leukocyte and porcine pancreatic elastase .

HY-15909

BCIP BCIP p-toluidine salt; X-phosphate p-toluidine salt	Fluorescent Dye	Others
BCIP(BCIP p-toluidine salt; X-phosphate p-toluidine salt) is an artificial chromogenic substrate used for the sensitive colorimetric detection of alkaline phosphatase activity .

HY-123275A

H-D-Phe-Pip-Arg-pNA hydrochloride 1 Publications Verification S-2238 hydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) hydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA hydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA hydrochloride is sensitive, accurate, and easy to perform .

HY-123275B

H-D-Phe-Pip-Arg-pNA acetate 1 Publications Verification S-2238 acetate	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) acetate, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA acetate is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA acetate is sensitive, accurate, and easy to perform .

HY-15914

DHBS DCHBS	Fluorescent Dye	Others
DHBS (3, 5-dichloro-2-hydroxybenzenesulfonate) is used in conjunction with 4-aminoantipyrine (4-AAP) (HY-W100990) and hydrogen peroxide (H₂O₂) for chromogenic quantitation of peroxidase in coupled enzymatic reactions. Component of Trinder reagent for use with peroxidase to measure generation of hydrogen peroxide in automated systems .

HY-15930A

TMB dihydrochloride 5+ Cited Publications BM blue dihydrochloride; Sure Blue TMB dihydrochloride	Fluorescent Dye Reactive Oxygen Species (ROS)	Others
TMB dihydrochloride is the dihydrochloride form of TMB (HY-15930). TMB dihydrochloride is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB dihydrochloride can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB dihydrochloride can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-W039892

4-Nitrophenyl β-D-glucuronide 1 Publications Verification pNPG_1	β-glucuronidase	Others
4-Nitrophenyl β-D-glucuronide (pNPG_1) is aderivative of 4-Nitrophenol. 4-Nitrophenyl β-D-glucuronide is the chromogenic substrate for β-glucuronidase .

HY-114522

X-alpha-Gal	Biochemical Assay Reagents	Others
X-alpha-Gal is a chromogenic substrate that is used to screen colonies with high activity of β-galactopyranoside. X-alpha-Gal also detects α-galactosidase activity. X-alpha-Gal can be used in yeast two hybrid screening for MEL1 gene activation. X-alpha-Gal can be used with Matchmaker GAL4-based products to confirm protein interactions .

HY-P3936

Endotoxin Substrate	Fluorescent Dye	Others
Endotoxin Substrate (Boc-LGR-pNA) is a chromogenic substrate can be used in quantitative assays of endotoxin .

HY-108775A

Sodium thiosulfate (99%, water≤1.0%) Sodium hyposulfite (99%, water≤1.0%)	Environmental Pollutants Biochemical Assay Reagents COX Interleukin Related NF-κB β-catenin GSK-3	Cardiovascular Disease Neurological Disease Inflammation/Immunology Endocrinology Cancer
Sodium thiosulfate is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease .

HY-P4202

Suc-Ala-Glu-Pro-Phe-pNA Suc-AEPF-pNA	Biochemical Assay Reagents	Others
Suc-Ala-Glu-Pro-Phe-pNA (Suc-AEPF-pNA) is a chromogenic substrate for the peptidyl-prolyl isomerase Pin1. Suc-Ala-Glu-Pro-Phe-pNA is used to evaluate the inhibitory effect of target compounds on Pin1, the catalytic activity of Pin1, and other related assays .

HY-16710

GPDA 1 Publications Verification GPN; Glycylproline p-nitroanilide tosylate	Fluorescent Dye	Others
GPDA (GPN; Glycylproline p-nitroanilide tosylate) is a chromogenic substrate of prolyl dipeptidyl aminopeptidase. GPDA is used to detect the activity of prolyl dipeptidyl aminopeptidase in human serum .

HY-P3949

Fluorescent Substrate for Glu-Specific Proteases	Fluorescent Dye	Others
Fluorescent Substrate for Glu-Specific Proteases is a V8 protease-Specific chromogenic substrate .

HY-153829

CH3OCO-D-CHA-Gly-Arg-pNA acetate	Factor Xa	Cardiovascular Disease
CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa .

HY-32264

X-Neu5Ac sodium X-NeuNAc	Bacterial	Others
X-Neu5Ac (sodium) is a substrate for chromogenic assay of neuraminidase activity in bacterial expression systems; with a K_m of 0.89 mM for neuraminidase.

HY-52112

BCDA 1 Publications Verification 5-bromo-4-chloroindoxyl acetate	Fluorescent Dye	Others
BCDA (5-bromo-4-chloroindoxyl acetate) is a chromogenic substrate of esterase used to potently detect the activity of esterase .

HY-W009454

Potassium p-nitrophenyl sulfate 4-Nitopheyl Sulfate potassium	Fluorescent Dye	Others
Potassium p-nitrophenyl sulfate (4-Nitophenyl Sulfate potassium) serves as a chromogenic substrate for arylsulfatases. Potassium p-nitrophenyl sulfate releases nitrophenol under the cleavage action of arylsulfatases, and the activity of arylsulfatases can be quantitatively determined via colorimetric detection at 400 nm. Potassium p-nitrophenyl sulfate is commonly used in enzyme inhibition assays and metabolite analog-related studies .

HY-P0021A

D-Lys(Z)-Pro-Arg-pNA diacetate 1 Publications Verification Spectrozyme PCa; Chromozym Pca diacetate	Fluorescent Dye	Others
D-Lys(Z)-Pro-Arg-pNA diacetate is a chromogenic peptide substrate of activated protein C (APC) .

HY-15930B

TMB dihydrochloride x.hydrate Maximum Cited Publications 6 Publications Verification Sure Blue TMB dihydrochloride x.hydrate	Fluorescent Dye Reactive Oxygen Species (ROS)	Others
TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-137799

NOBA	Biochemical Assay Reagents	Others
NOBA is a synthetic chromogenic substrate that can be used to detect the enzyme activity of AplTX-II. NOBA can be used in the research of phospholipid hydrolysis .

HY-W015996

4-Nitrophenyl-N-acetyl-α-D-galactosaminide pNP-GalNAc	Fluorescent Dye	Others
4-Nitrophenyl-N-acetyl-α-D-galactosaminide (pNP-GalNAc) can be used as a chromogenic substrate for N-acetyl-D-galactosaminase. 4-Nitrophenyl-N-acetyl-α-D-galactosaminide is cleaved by N-acetyl-D-galactosaminase to generate a yellow solution. The enzyme activity is quantitatively determined by absorbance detection .

HY-P10094

β-Ala-Gly-Arg-pNA	Fluorescent Dye	Others
β-Ala-Gly-Arg-pNA is a chromogenic substrate of thrombin with pNA a strong absorbance at 405 nm .

HY-P4518

Z-Val-Gly-Arg-pNA	Ser/Thr Protease	Others
Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. Z-Val-Gly-Arg-pNA can be used for determination of urokinase activity .

HY-P4460

AAA-pNA	Ser/Thr Protease	Cancer
AAA-pNA is a chromogenic substrate of Tripeptidyl-peptidase II. AAA-pNA can be used to test Tripeptidyl-peptidase II activity .

HY-112276

Beryllon II	Fluorescent Dye	Others
Beryllon II is a widely used chromogenic reagent that is used to determine many elements, such as Mo, Mg and Co, and also used for the determination of proteins.

HY-122142A

Pyr-Pro-Arg-pNA hydrochloride S-2366 hydrochloride	APC Factor XI Biochemical Assay Reagents	Others
Pyr-Pro-Arg-pNA (S2366) hydrochloride is a chromogenic peptide substrate for Factor XI and Activated protein C (APC). Pyr-Pro-Arg-pNA hydrochloride can induce noncompetitive inhibition of factor XI activation through occupancy of the active site of the factor XIa-light chain. Pyr-Pro-Arg-pNA hydrochloride can be used for measurement of APC amidolytic activity .

HY-123275C

H-D-Phe-Pip-Arg-pNA dihydrochloride S-2238 dihydrochloride	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform .

HY-15930C

TMB monosulfate 5+ Cited Publications BM blue monosulfate; Sure Blue TMB monosulfate	Fluorescent Dye Reactive Oxygen Species (ROS)	Others
TMB monosulfate is the monosulfate form of TMB (HY-15930). TMB monosulfate is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB monosulfate can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB monosulfate can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-P4484

Suc-AAPK-pNA	Biochemical Assay Reagents	Others
Suc-AAPK-pNA is a chromogenic substrate for the determination of serine/threonine kinase activity and enzyme kinetic parameters .

HY-P3934

HIV Protease Substrate I	HIV Protease	Infection
HIV Protease Substrate I is a chromogenic substrate of HIV-1 protease. HIV Protease Substrate I has the cleavage site of HIV protease .

HY-P4254

H-Gly-Glu-pNA	PAI-1 Ser/Thr Protease	Others
H-Gly-Glu-pNA is a chromogenic peptide substrate that can be widely used in enzymatic analysis, including trypsin and urokinase-type plasminogen activator (uPA) .

HY-123275

H-D-Phe-Pip-Arg-pNA S-2238	Fluorescent Dye	Others
H-D-Phe-Pip-Arg-pNA (S-2238), a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA is sensitive, accurate, and easy to perform .

HY-W328317

Fast garnet GBC sulfate salt, 90% Azoic diazo No. 4, 90%	Biochemical Assay Reagents	Others
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.

HY-W341421

3-Indoxyl butyrate	Biochemical Assay Reagents	Others
3-Indoxyl butyrate is a chromogenic substrate for CES (carboxylesterase), producing a blue precipitate upon cleavage.

HY-137837

D-Ile-Pro-Arg p-nitroanilide dihydrochloride 1 Publications Verification	Biochemical Assay Reagents	Others
D-Ile-Pro-Arg p-nitroanilide dihydrochloride is a chromogenic peptide substrate of tissue plasminogen activator (tPA) .

HY-P3126

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride	Factor Xa	Others
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate .

HY-P10145

Ac-LEVD-pNA	Biochemical Assay Reagents Caspase	Others
Ac-LEVD-pNA is a chromogenic substrate for caspase-4 and can be used to detect caspase-4 activity .

HY-P4458

Boc-QAR-pNA	Ser/Thr Protease	Cancer
Boc-QAR-pNA is a chromogenic substrate of trypsin. Boc-QAR-pNA can be used to test trypsin activity .

HY-P4482

Suc-AAPE-pNA	Bacterial	Infection
Suc-AAPE-pNA is a chromogenic substrate of glutamyl endopeptidase. Suc-AAPE-pNA can be used to test glutamyl endopeptidase activity .

HY-P4464

Ala-Phe-Pro-pNA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA can be used to test tripeptidyl peptidase activity .

HY-P4464A

Ala-Phe-Pro-pNA TFA	Ser/Thr Protease	Cancer
Ala-Phe-Pro-pNA TFA is a chromogenic substrate of tripeptidyl peptidase. Ala-Phe-Pro-pNA TFA can be used to test tripeptidyl peptidase activity .

Cat. No.	Product Name	Type

HY-15927

4-Nitrophenyl β-D-glucopyranoside

1 Publications Verification

Biochemical Assay Reagents

4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .

HY-W127711

Fast Blue B Salt, Dye content ~95%

Biochemical Assay Reagents

Fast Blue B Salt, Dye content ~95% is a diazo dye, primarily used as a chromogenic substrate in biochemical analysis. Fast Blue B Salt, Dye content ~95% is the coupling agent for the histochemical demonstration of proteases. Fast Blue B Salt, Dye content ~95% can be used for the detection of acid phosphatase in Clostridium perfringens, and also for the determination of lipase activity. Fast Blue B Salt, Dye content ~95% reacts directly with the active hydroxyl groups in phenolic compounds to determine the content of phenolic substances .

HY-15932

TOOS

TOOS sodium salt

Biochemical Assay Reagents

TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound .

HY-108775A

Sodium thiosulfate (99%, water≤1.0%)

Sodium hyposulfite (99%, water≤1.0%)

Biochemical Assay Reagents

Sodium thiosulfate is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease .

HY-W129633

2,6-Dichlorophenolindophenol sodium hydrate

1 Publications Verification

DCIP sodium hydrate; DPIP sodium hydrate

Biochemical Assay Reagents

2,6-Dichlorophenolindophenol (DCIP; DPIP) sodium hydrate is a redox chromogenic indicator with a redox potential of +217 mV relative to SHE, and it acts as a substrate for reduction reactions. During the metabolic process of nutrient consumption by Saccharomyces cerevisiae, 2,6-Dichlorophenolindophenol sodium hydrate is reduced from dark blue to colorless, resulting in a decrease in absorbance. 2,6-Dichlorophenolindophenol sodium hydrate is widely used in spectrophotometric biochemical oxygen demand determination and preclinical colorimetric toxicity analysis for heavy metal ion detection based on Saccharomyces cerevisiae .

HY-137822

p-Nitrophenyl α-D-mannopyranoside

4-Nitrophenyl a-D-mannopyranoside

Biochemical Assay Reagents

p-Nitrophenyl α-D-mannopyranoside (4-Nitrophenyl α-D-mannopyranoside) is a chromogenic glycosidic ligand. p-Nitrophenyl α-D-mannopyranoside features a sugar moiety (α-D-mannopyranose) with the mannose-characteristic axial hydroxyl group at the C2 position and a ligand portion (p-nitrophenol) that provides ultraviolet-visible light absorption properties. p-Nitrophenyl α-D-mannopyranoside can be used to determine glycosidase activity and characterize the sugar recognition properties of lectins (such as Concanavalin A (HY-P2149)) .

HY-15933

TOPS 1 Publications Verification	Biochemical Assay Reagents
TOPS is a chromogenic substrate. TOPS undergoes an oxidative coupling reaction with 4-aminoantipyrine in the presence of H₂O₂ and nanocrystalline cobalt selenide. TOPS is used in studies related to uric acid detection .

HY-D0007

Blue Tetrazolium

Tetrazolium blue

Biochemical Assay Reagents

Blue Tetrazolium is a tetrazolium salt chromogenic dye that can be reduced to a dark blue formazan product. Blue Tetrazolium is applicable for assays such as succinate dehydrogenase activity detection and reducing sugar quantification. Blue Tetrazolium also serves as a novel corrosion inhibitor for cold-rolled steel in hydrochloric acid solutions. Blue Tetrazolium has a broad wavelength range (480-600 nm), with the maximum absorbance observed at 540 nm .

HY-137878

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid

PNP-α-NeuNAc

Biochemical Assay Reagents

2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) is a classic chromogenic substrate for neuraminidase. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid releases p-nitrophenol upon enzymatic hydrolysis, allowing quantification of enzyme activity and inhibitory effects via spectrophotometry. 2-O-(p-Nitrophenyl)-α-D-N-acetylneuraminic acid (PNP-α-NeuNAc) acts as a sialyl donor in the process of enzyme-catalyzed trans-sialylation .

HY-15930B

TMB dihydrochloride x.hydrate

Maximum Cited Publications

6 Publications Verification

Sure Blue TMB dihydrochloride x.hydrate

Biochemical Assay Reagents

TMB (dihydrochloride x.hydrate) is the dihydrochloride x hydrate form of TMB (HY-15930). TMB (dihydrochloride x.hydrate) is a non-toxic, non-mutagenic, colorless dye that is also used as a chromogenic agent in enzyme detection systems based on horseradish peroxidase (HRP). TMB (dihydrochloride x.hydrate) can function as a photoacoustic probe for reactive oxygen and nitrogen species (ROS/RNS), reacting with hypochlorite, hydrogen peroxide, singlet oxygen, and nitrogen dioxide to produce blue oxidation products. TMB (dihydrochloride x.hydrate) can detect the singlet oxygen produced by the outer membrane of Escherichia coli ATCC 25922 .

HY-137779

5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside

Biochemical Assay Reagents

5-Bromo-4-chloro-3-indolyl β-D-glucopyranoside, a chromogenic substrate for the detection of β-galactosidase activity. It is commonly used in molecular biology techniques such as gene expression analysis and reporter gene analysis. When β-galactosidase cleaves X-Gluc, a blue precipitate is produced, which can be observed by microscopy or other detection methods. X-Gluc has high sensitivity and specificity for the detection of β-galactosidase activity, making it a widely used tool in molecular biology research.

HY-D1208

Alkaline phosphatase substrate	Biochemical Assay Reagents
Alkaline phosphatase substrate is a chemiluminescent substrate for alkaline phosphatase. Alkaline phosphatase substrate can be used for enzyme-linked immunoassays .

HY-W328317

Fast garnet GBC sulfate salt, 90% Azoic diazo No. 4, 90%	Biochemical Assay Reagents
Fast garnet GBC sulfate salt, 90% is a chromogenic substrate for alkaline phosphatase.

HY-W341421

3-Indoxyl butyrate	Biochemical Assay Reagents
3-Indoxyl butyrate is a chromogenic substrate for CES (carboxylesterase), producing a blue precipitate upon cleavage.

HY-15919

HTBA 3-Hydroxy-2,4,6-triiodobenzoic acid	Biochemical Assay Reagents
HTBA (3-Hydroxy-2,4,6-triiodobenzoic acid) is a biochemical reagent and important intermediate. HTBA can be used in the research of life science, organic chemistry and other fields .

HY-W127380

Arachidonoyl thio-PC

Biochemical Assay Reagents

Arachidonoyl Thio-PC is a substrate of many phospholipase A2 (PLA2), including sPLA2, cPLA2 and iPLA2. Cleavage of sn-2 fatty acids by PLA2 results in the production of free thiols, which react with chromogenic reagents such as DTNB (Ellman's reagent) and DTP, allowing quantification of PLA2 activity. Isozyme-specific cPLA2 activity can be measured by depleting or inhibiting sPLA2 and iPLA2 activity in the assay.

HY-15905

ALPS N-Ethyl-N-sulfopropylaniline sodium salt	Biochemical Assay Reagents
ALPS(N-Ethyl-N-sulfopropylaniline sodium salt) is a bio-chemical reagents/chromogenic reagent.

HY-137895

L-Arginine p-nitroanilide dihydrochloride, 98% H-Arg-pNA 2HCl, 98%	Biochemical Assay Reagents
L-Arginine p-nitroanilide dihydrochloride, 98% (H-Arg-pNA 2HCl, 98%) is a chromogenic substrate for cathepsin H and aminopeptidases.

HY-W009022

Diantipyrylmethane	Biochemical Assay Reagents
Diantipyrylmethane is a chromogenic reagent commonly used for the determination of the contents of metals such as Au (III), Ti (IV), Ir, Fe (III), molybdenum, neodymium, U (IV), iridium, platinum and rhenium via spectrophotometry and extraction photometry. Diantipyrylmethane can also form a fluorescent complex with Er (III) ions, which is applied to the determination of erbium .

HY-D1224A

Chlorophenol red β-D-galactopyranoside sodium

CPRG sodium

Biochemical Assay Reagents

Chlorophenol red-β-D-galactopyranoside (CPRG) sodium is an efficient and sensitive chromogenic substrate for β-galactosidase (HY-P2869), widely used in colorimetric assays. Chlorophenol red-β-D-galactopyranoside sodium itself appears pale yellow. When it is specifically hydrolyzed by β-galactosidase, it releases chlorophenol red. The released chlorophenol red turns purple-red under alkaline or neutral pH conditions. This color change from yellow to red can be quantitatively detected at wavelengths of 540-572 nm using visible spectrophotometry .

HY-137228

4-Nitrophenylmaltohexaoside	Biochemical Assay Reagents
4-Nitrophenylmaltohexaoside is a chromogenic substrate targeting α-amylase.

HY-W013758

TMB-PS sodium TMBZ-PS sodium	Biochemical Assay Reagents
TMB-PS (TMBZ-PS) sodium is a chromogenic substrate for the detection and quantification of peroxidase activity .

HY-W290273

2-Nitrophenyl-β-D-thiogalactopyranoside 2-Nitrophenyl-beta-D-thiogalactopyranoside	Biochemical Assay Reagents
2-Nitrophenyl-β-D-thiogalactopyranoside is a chromogenic substrate used to detect the presence of galactosidase in various biological and biochemical assays.

HY-W011655

p-Nitrophenyl α-D-xylopyranoside p-Nitrophenyl alpha-D-xylopyranoside	Biochemical Assay Reagents
p-Nitrophenyl α-D-xylopyranoside (p-Nitrophenyl alpha-D-xylopyranoside) is a chromogenic substrate for α-xylosidase .

HY-138821

BCIP potassium	Biochemical Assay Reagents
BCIP (potassium) is a chromogenic substrate commonly used to detect the enzymatic activity of alkaline phosphatase. When dephosphorylated by alkaline phosphatase, BCIP produces a blue precipitate.

HY-W283889

Blue caprate	Biochemical Assay Reagents
Blue caprate is a chromogenic enzyme substrate typically used to detect lipase activity. It is hydrolyzed by lipase to produce a blue-purple product (biosynth: EB04034).

HY-W291944

5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside	Biochemical Assay Reagents
5-Bromo-4-chloro-3-indolyl-α-L-fucopyranoside can be used as a chromogenic substrate for α-L-Fucosidase.

HY-137785

2-Chloro-4-nitrophenyl-β-D-maltotrioside	Biochemical Assay Reagents
2-Chloro-4-nitrophenyl-β-D-maltotrioside is a chromogenic substrate used in bioluminescent and fluorescent assays to detect α-amylase.

HY-W288676

6-Fluoro-3-indolyl-β-D-galactopyranoside	Biochemical Assay Reagents
6-Fluoro-3-indolyl-β-D-galactopyranoside is a chromogenic enzyme substrate commonly used in microbiology to detect the expression of β-galactosidase in bacterial colonies.

HY-W293502

2-Chloro-4-nitrophenyl-β-D-galactopyranoside 2-Chloro-4-nitrophenyl-beta-D-galactopyranoside	Biochemical Assay Reagents
2-Chloro-4-nitrophenyl-β-D-galactopyranoside is a chromogenic substrate used for testing enzyme activity. It is commonly used in molecular biology research to detect and measure the activity of β-galactosidase (biosynth: EC03318).

HY-W101382

5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98%	Biochemical Assay Reagents
5-Bromo-6-chloro-3-indolyl-N-acetyl-β-D-glucosaminide, 98% is a chromogenic substrate used to measure β-galactosidase activity in food, enzyme substrates, and culture media.

HY-W104635

6-Bromo-2-naphthyl-β-D-galactopyranoside 6-Bromo-2-naphthyl-beta-D-galactopyranoside	Biochemical Assay Reagents
6-Bromo-2-naphthyl-β-D-galactopyranoside is a chromogenic substrate commonly used to measure β-galactosidase enzyme activity in food, enzyme substrates, and culture media. Upon hydrolysis by β-galactosidase, it generates a yellow precipitate indicating the enzyme's presence.

HY-W854392

3-Carboxyumbelliferyl-β-D-glucuronide dipotassium

Biochemical Assay Reagents

3-Carboxyumbelliferyl-β-D-glucuronide (dipotassium) is a chromogenic substrate with biological activity for enzyme activity detection. 3-Carboxyumbelliferyl-β-D-glucuronide (dipotassium) can be used to evaluate biological reactions associated with glycosidases. 3-Carboxyumbelliferyl-β-D-glucuronide (dipotassium) shows a wide range of application potentials in compound discovery and biomedical research.

HY-157926

Nitroso-PSAP	Biochemical Assay Reagents
Nitroso-PSAP is a sensitive and specific chromogenic reagent for iron (Fe ²⁺), which is used for the colorimetric determination of iron in blood after mineralization with periodic acid. TNitroso-PSAP chelates with iron (Fe ²⁺) to produce a green complex (λmax=756 nm, Epsilon = 4.5 x 10 < sup > 4 < / sup > dm < sup > 3 < / sup > mol < sup > 1 < / sup > cm < sup > 1 < / sup >) .

HY-W698964

2′-Hydroxy-5′-nitrohexadecanamide

Biochemical Assay Reagents

2′-Hydroxy-5′-nitrohexadecanamide is a lysosomal hydrolase inhibitor and is a lipid containing pentadecanoic acid and a terminal nitrophenol in its structure. 2′-Hydroxy-5′-nitrohexadecanamide can cause intracellular lipid accumulation by inhibiting lysosomal hydrolase activity. Additionally, 2′-Hydroxy-5′-nitrohexadecanamide can be used to synthesize chromogenic substrates for measuring sphingolipase activity .

HY-W794825

Basic Green 5	Biochemical Assay Reagents
Basic Green 5 is a biological material or organic compound that can be used in life science research .

HY-W134020

Semixylenol orange Semixylenol orange	Biochemical Assay Reagents
Semixylenol orange is a metallochromic indicator that can complex with various metal ions and is used for the testing and analysis of metal ions such as zinc and zirconium .

HY-W638077

6-Chloro-3-indoxyl caprylate	Biochemical Assay Reagents
6-Chloro-3-indoxyl caprylate is a chromogenic substrate with C8 activity for esterases.

HY-W292085

6-Chloro-1H-indol-3-yl β-D-glucopyranoside	Biochemical Assay Reagents
6-Chloro-1H-indol-3-yl β-D-glucopyranoside can be used to detect chromogenic medium for studying yeast with β-glucosidase activity .

HY-W587779

o-Nitrophenyl β-D-galactopyranoside-6-phosphate cyclohexylammonium	Biochemical Assay Reagents
o-Nitrophenyl β-D-galactopyranoside-6-phosphate cyclohexylammonium is a chromogenic substrate with activity for β-galactosidase detection. The use of o-Nitrophenyl β-D-galactopyranoside-6-phosphate cyclohexylammonium can help researchers quickly identify and quantify β-galactosidase activity.

Cat. No.	Product Name

HY-K0324

Total Superoxide Dismutase (SOD) Activity Colorimetric Assay Kit (Xanthine Oxidase-NBT Method)

MCE MCE Total Superoxide Dismutase (SOD) Activity Colorimetric Assay Kit (Xanthine Oxidase-NBT Method) is based on the xanthine oxidase–NBT chromogenic system and quantitatively determines total SOD activity in various biological samples by measuring the inhibition of NBT reduction to formazan in the xanthine/xanthine oxidase–generated superoxide system at 560 nm. It is suitable for the determination of SOD activity in cell or tissue homogenate supernatants, whole blood, erythrocyte extracts, serum, and other biological samples.

Cat. No.	Product Name	Target	Research Area	Image

HY-P99016B

Enfortumab vedotin-ejfv (solution) 1 Publications Verification	Antibody-Drug Conjugates (ADCs) Nectin-4	Cancer
Enfortumab vedotin-ejfv (solution) is an anti-Nectin-4 antibody-drug conjugate (ADC). Enfortumab vedotin-ejfv (solution) is a fully humanized IgG1 antibody conjugated to the microtubule disrupting agent MMAE (HY-15162) via a protease-cleavable Val-Cit linker. The antibody portion is Enfortumab (HY-P99016), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Nectin-4 is an adhesion protein involved in cellular processes and tumorigenesis, and Enfortumab vedotin-ejfv (solution) is indicated for the inhibition of locally advanced or metastatic urothelial carcinoma .

HY-132253

Polatuzumab vedotin 1 Publications Verification	Antibody-Drug Conjugates (ADCs) Transmembrane Glycoprotein	Cancer
Polatuzumab vedotin is an antibody-drug conjugate targeting CD79b. It contains a humanized anti-CD79b IgG1 monoclonal antibody linked to monomethyl auristatin E (MMAE), a potent microtubule inhibitor. The antibody portion is Polatuzumab (HY-P99042), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Polatuzumab vedotin has the potential for the research of Large B-cell lymphomas (LBCL) .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-12591A

D-Luciferin 105+ Cited Publications D-(-)-Luciferin; Firefly luciferin; Beetle Luciferin	Natural Products Animals Other Diseases Disease Research Fields Source Classification	Fluorescent Dye
D-luciferin is the natural substrate of the enzyme luciferase (Luc) that catalyzes the production of the typical yellowgreen light of fireflies. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase concentration when the substrate luciferin is present in excess. The luciferase (luc) gene is a popular reporter gene for research and agent screening. Chemiluminescent techniques are virtually background-free, making the luc reporter gene ideal for detecting low-level gene expression. As little as 0.02 pg of luciferase can be reliably measured in a standard scintillation counter. In addition to its role as a reporter of gene expression, luciferase is commonly used in an extremely sensitive assay for ATP . We of er the firefly luciferase (HY-P1004A), luciferin free acid (HY-12591A), as well as its water-soluble sodium salts (HY-12591) and potassium salts (HY-12591B) .

HY-N0116

Hematoxylin 10+ Cited Publications Natural Black 1; Haematoxylin	Classification of Application Fields Leguminosae Caesalpinia sappan L. Other Diseases Phenols Polyphenols Plants Disease Research Fields Source Classification	Amyloid-β
Hematoxylin (Natural Black 1), a naturally occurring flavonoid compound derived from Caesalpinia sappan Linn.. Hematoxylin is a nuclear stain in histology and is also a potent Aβ42 fibrillogenesis inhibitor with an IC₅₀ of 1.6 μM.

HY-113245

3-Indolyl-β-D-glucuronide	Alkaloids Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Indole Alkaloids Source Classification	Endogenous Metabolite
3-Indolyl-β-D-glucuronide, a chromogenic substrate for β-D-glucuronidase, employs in the detection and enumeration of E. coli, yielding a blue precipitate upon cleavage. 3-Indolyl-β-D-glucuronide in? patients' plasma act as a new indicator of renal failure .

Cat. No.	Product Name	Chemical Structure

HY-D0233S

Leucocrystal violet-d6

Leucocrystal violet-d₆ is the deuterium labeled Leucocrystal violet (HY-D0233). Leucocrystal violet is a cationic triarylmethane dye. Leucocrystal violet generates a colored purple product in the presence of hydrogen peroxide and horseradish peroxidase, or when oxidized by periodate under the catalysis of horseradish peroxidase. Leucocrystal violet serves as a chromogenic reagent for the determination of submicrogram-level hydrogen peroxide, with no interference from tryptophan, persulfate or chromate. Leucocrystal violet reacts with blood to produce a purple/violet color in the presence of hydrogen peroxide; it forms a very weak fluorophore when acting with whole blood in an unbuffered solution, with a maximum absorption wavelength of 630 nm and a maximum fluorescence emission wavelength of 665 nm upon excitation at 630 nm. Leucocrystal violet is widely used for staining blood residues on porous and non-porous materials.

HY-W707394

NOBA-d15
NOBA-d₁₅ is the deuterium labeled NOBA (HY-137799). NOBA is a synthetic chromogenic substrate that can be used to detect the enzyme activity of AplTX-II. NOBA can be used in the research of phospholipid hydrolysis .

Cat. No.	Product Name		Classification

HY-D0995

7-Methyl-6-thioguanosine 2 Publications Verification MESG		Nucleoside Analogs Guanosine
7-Methyl-6-thioguanosine (MESG) is a chromogenic substrate that can be converted to 7-methyl-6-thioguanine in the presence of purine nucleoside phosphorylase and inorganic phosphate. 7-Methyl-6-thioguanosine can be used to quantify inorganic phosphate. 7-Methyl-6-thioguanosine can also be used to determine the activities of purine nucleoside phosphorylase and protein phosphatases .

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