2 Results for "

colon neoplastic lesions

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "colon neoplastic lesions" in MCE Product Catalog:

1
(+)-(3R,8S)-Falcarindiol
(+)-(3R,8S)-Falcarindiol
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1 Cited Publications
Cat. No.: HY-N1976
CAS No.: 225110-25-8
Synonyms: (3R,8S)-Falcarindiol; 3(R),8(S),9(Z)-Falcarindiol
Category:  

Infection Natural Products Decachaeta ovatifolia (DC.) R.M.King & H.Rob. Plants Umbelliferae Disease Research Fields Inflammation/Immunology

(+)-(3R,8S)-Falcarindiol ((3R,8S)-Falcarindiol; 3 (R),8 (S),9 (Z)-Falcarindiol) is an orally active polyacetylene anti-mycobacterial agent. (+)-(3R,8S)-Falcarindiol exhibits antibacterial activity against Gram-positive bacteria, Gram-negative bacteria and mycobacteria. Co-administration of (+)-(3R,8S)-Falcarindiol with (3R)-falcarinol alters the composition of gut microbiota, reduces colonic tumor lesions and slows down polyp growth. (+)-(3R,8S)-Falcarindiol can be used in research related to tuberculosis and colorectal cancer .
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HFB200901
HFB200901
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Cat. No.: HY-P992366

Target:  

Galectin Tim3

Research Areas:  

Cancer

HFB200901 is a galectin LGALS9 inhibitor and immunostimulant that can be used in studies related to pancreatic adenocarcinoma, pancreatic intraepithelial neoplasia, KRAS G12C-mutant colon cancer, and prostate cancer. HFB200901 disrupts the LGALS9/TIM-3 axis, while blocking the internalization and vacuolization of recombinant LGALS9. HFB200901 reduces the proportion of regulatory T cells (Treg) and enhances dendritic cell activation, thereby inducing polyfunctional and memory CD8 + T cell responses. HFB200901 inhibits the progression of pancreatic neoplastic lesions and effectively improves the efficacy of PSMA-based vaccination .
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