1 Result for "

cxcr3+inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "cxcr3+inhibitor" in MCE Product Catalog:

Cat. No.: HY-184899
Target:  

Sirtuin CXCR Dengue Virus

Research Areas:  

Infection Inflammation/Immunology

Sirt1/CXCR3-IN-1 is a dual Sirt1/CXCR3 inhibitor with an IC50 of 0.77 μM against Sirt1. Sirt1/CXCR3-IN-1 inhibits dengue virus replication, upregulates the expression of interferon-stimulated genes, and enhances the antiviral defense capacity of the host. Sirt1/CXCR3-IN-1 suppresses CXCR3-mediated T cell chemotaxis and cytokine release, thereby reducing immune activation and inflammatory responses. Sirt1/CXCR3-IN-1 is applicable to research related to dengue virus infection .
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