3 Results for "

de novo cholesterol biosynthesis

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "de novo cholesterol biosynthesis" in MCE Product Catalog:

Cat. No.: HY-43515
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

ESI1 is a small molecule epigenetic silencing inhibitor. ESI1 can trigger the formation of nuclear condensates of key lipid metabolism regulators SREBP1/2, concentrating transcriptional co-activators to drive lipid/cholesterol biosynthesis. ESI1 can promote myelin regeneration in demyelinated animal models and facilitate de novo myelination on regenerating CNS axons, reversing age-related declines in cognitive abilities .
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Cat. No.: HY-157528
CAS No.: 3047118-54-4
CJ28 is a cortisol biosynthesis inhibitor that significantly inhibits basal and stimulated cortisol production in human adrenal carcinoma cell lines. CJ28 exhibits inhibitory effects by reducing steroidogenesis and de novo cholesterol biosynthesis .
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Cat. No.: HY-157828
CAS No.: 2376765-57-8
Research Areas:  

Neurological Disease Cancer

DSP-0390 is an orally active inhibitor of emopamil binding protein (EBP). DSP-0390 induces cell death by blocking cholesterol biosynthesis in tumor cells. DSP-0390 exhibits antitumor activity in an orthotopic xenograft model of human glioblastoma. DSP-0390 can be used for the research of recurrent high-grade gliomas .
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