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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
eukaryotic initiation factor 4A
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "eukaryotic initiation factor 4A" in MCE Product Catalog:
53
53 Publications Verification
Synonyms: (-)-Silvestrol
1
1 Cited Publications
Research Areas:
eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM .
Cat. No.: HY-19356A
CAS No.: 177262-30-5
Research Areas:
Didesmethylrocaglamide, a derivative of Rocaglamide, is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. Didesmethylrocaglamide has potent growth-inhibitory activity with an IC50 of 5 nM. Didesmethylrocaglamide suppresses multiple growth-promoting signaling pathways and induces apoptosis in tumor cells. Antitumor activity .
Cat. No.: HY-176844
CAS No.: 3083978-00-8
Target:
Research Areas:
eIF4A-IN-1 intermediate (Compound 71E) is an intermediate of Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-1 intermediate can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-176843
CAS No.: 3083974-69-7
Research Areas:
eIF4A-IN-2 (Compound 93) is an Eukaryotic translation initiation factor 4A (eIF4A) inhibitor. eIF4A-IN-2 can be used as a cytotoxic payload for synthesis of antibody-drug conjugates (ADCs) .
Cat. No.: HY-145360
CAS No.: 2100133-77-3
Research Areas:
eIF4A3-IN-6 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-6 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) .
Cat. No.: HY-145359
CAS No.: 2100145-31-9
Research Areas:
eIF4A3-IN-5 is a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII. eIF4A3-IN-5 has the potential for the research of eIF4A dependent diseases, including the research of cancer (extracted from patent US20170145026A1) .
Cat. No.: HY-129768
CAS No.: 2368900-33-6
Research Areas:
CMLD012072 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012072 can induce RNA clamping of eIF4A1 and eIF4A2 and possess potent anti-neoplastic activity .
Cat. No.: HY-129767
CAS No.: 2368900-35-8
Research Areas:
CMLD012612 is an amidino-rocaglate containing a hydroxamate group and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012612 inhibits cell translation and is cytotoxic to NIH/3T3 cells with an IC50 value of 2 nM. CMLD012612 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) and possesses potent anti-neoplastic activity .
Cat. No.: HY-129769
CAS No.: 2368900-32-5
Research Areas:
CMLD012073 is an amidino-rocaglates and is a potent eukaryotic initiation factor 4A (eIF4A) inhibitor. CMLD012073 inhibits the growth of NIH/3T3 cells with an IC50 of 10 nM. CMLD012073 inhibits eukaryotic translation initiation by modifying the behavior of the RNA helicase (eIF4A) .
Cat. No.: HY-43913
CAS No.: 2095484-82-3
Research Areas:
(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM .
Cat. No.: HY-P701605
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF4A1; eukaryotic initiation factor 4AI; Prev. EIF4A; EIF4A-I; DDX2A; eukaryotic Translation initiation factor 4A, Isoform 1; EIF-4A; eukaryotic Translation initiation factor 4A; ATP-Dependent RNA Helicase EIF4A-1; ATP-Dependent RNA Helicase; eukaryotic
Species:
Human
Source:
E. coli
Cat. No.: HY-P701606
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: EIF4A1; eukaryotic initiation factor 4AI; Prev. EIF4A; EIF4A-I; DDX2A; eukaryotic Translation initiation factor 4A, Isoform 1; EIF-4A; eukaryotic Translation initiation factor 4A; ATP-Dependent RNA Helicase EIF4A-1; ATP-Dependent RNA Helicase; eukaryotic
Species:
Human
Source:
E. coli
Cat. No.: HY-101785R
CAS No.: 2095677-20-4
Research Areas:
eIF4A3-IN-2 (Standard) is the analytical standard of eIF4A3-IN-2 (HY-101785). This product is intended for research and analytical applications. eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM .
Cat. No.: HY-P87157
Synonyms: ATP dependent RNA helicase eIF4A 2 antibody; ATP-dependent RNA helicase eIF4A-2 antibody; BM-010 antibody; DDX2B antibody; eIF 4A II antibody; eIF-4A-II antibody; EIF4A antibody; eIF4A II antibody; eIF4A-II antibody; EIF4A2 antibody; ATP dependent RNA helicase eIF4A 2 antibody; ATP-dependent RNA helicase eIF4A-2 antibody; BM-010 antibody; DDX2B antibody; eIF 4A II antibody; eIF-4A-II antibody; EIF4A antibody; eIF4A II antibody; eIF4A-II antibody; EIF4A2 antibody; EIF4F antibody; eukaryotic initiation factor 4A II antibody; eukaryotic initiation factor 4A-II antibody; eukaryotic translation initiation factor 4A isoform 2 antibody; eukaryotic translation initiation factor 4A2 antibody; IF4A2_HUMAN antibody; N-terminally processed antibody;
Cat. No.: HY-P700526
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: EIF4A2; ATP-Dependent RNA Helicase EIF4A-2; Prev. EIF4F; EIF4A-II; DDX2B; eukaryotic Translation initiation factor 4A, Isoform 2; BM-010; ATP-Dependent RNA Helicase; EIF4A; RNA Helicase; eukaryotic initiation factor 4A-II; NEDHSS; eukaryotic Translation I
Species:
Human
Source:
E. coli
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
