2 Results for "

eukaryotic mitochondrial membranes

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "eukaryotic mitochondrial membranes" in MCE Product Catalog:

Cat. No.: HY-P10285
CAS No.: 286380-05-0
Synonyms: D-(KLAKLAK)2
Research Areas:  

Cancer

d-KLA Peptide (D-(KLAKLAK)2), KLA peptide (HY-P5345) isomer, is a pro-apoptosis peptide. d-KLA Peptide can specifically target mitochondria and induce apoptosis by destroying the mitochondrial membrane. d-KLA Peptide increases caspase 3/7 activity, exerts proapoptotic activity and enhances antitumor efficacy in mouse melanoma models .
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Cat. No.: HY-P10370B
Target:  

Apoptosis Caspase

Research Areas:  

Cancer

d-(KLAKLAK)2, Proapoptotic Peptide acetate is a pro-Apoptotic peptide whose core mechanism of action is to disrupt organelle membranes, especially mitochondrial membranes, thereby inducing apoptosis. d-(KLAKLAK)2, Proapoptotic Peptide acetate activates the activity of caspase 3/7 in cancer cells. Although d-(KLAKLAK)2 Proapoptotic Peptide acetate exhibits very low toxicity to eukaryotic cells extracellularly, it cannot effectively penetrate cell membranes to enter the cytoplasm on its own. d-(KLAKLAK)2, Proapoptotic Peptide acetate must be conjugated with a carrier capable of "homing" and "internalization" to exert its anti-cancer effects .
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