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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
fat oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "fat oxidation" in MCE Product Catalog:
28
28 Cited Publications
Category:
Alkaloids Neurological Disease Animals Anti-aging Pyridine Alkaloids Metabolic Disease Disease Research Fields
Target:
28
28 Cited Publications
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
28
28 Cited Publications
Cat. No.: HY-123033B
CAS No.: 2415657-86-0
Category:
Natural Products Neurological Disease Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
6
6
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
3
3 Cited Publications
Synonyms: L-Ascorbic acid 6-hexadecanoate; 6-O-Palmitoyl-L-ascorbic acid
2
2 Cited Publications
Synonyms: Malonyl coenzyme A lithium
Research Areas:
Malonyl CoA (Malonyl Coenzyme A) lithium is an inhibitor of carnitine palmitoyl transferase 1 (CPT1). High Malonyl CoA lithium concentrations suppress fatty acid oxidation, while low Malonyl CoA lithium concentrations are permissive for fat oxidation .
1
1
Research Areas:
Perfluorobutanesulfonic acid (PFBS) is a short-chain perfluoroalkyl substance and the main replacement for perfluorooctanesulfonic acid. Perfluorobutanesulfonic acid induces fat accumulation in human HepG2 hepatoma cells. Perfluorobutanesulfonic acid promotes lipid accumulation by activating PPARγ pathway and triggering oxidative stress, endoplasmic reticulum stress and calcium dyshomeostasis. Perfluorobutanesulfonic acid impairs reproduction and causes developmental disorders in offspring of Caenorhabditis elegans. Perfluorobutanesulfonic acid disrupts pancreatic organogenesis and lipid homeostasis in zebrafish embryos. Perfluorobutanesulfonic acid can be used in environmental toxicology, lipid metabolism and developmental toxicity studies .
Cat. No.: HY-W018026
CAS No.: 32462-30-9
Synonyms: L-p-Hydroxyphenylglycine; 4-Hydroxy-L-phenylglycine; UK 25842
Target:
Research Areas:
Oxfenicine (L-p-Hydroxyphenylglycine) is an orally active carnitine palmitoyltransferase-1 inhibitor. Oxfenicine inhibits the oxidation of fatty acids in the heart, protecting cardiac tissue from necrotic damage during ischemia, and also has an inhibitory effect on cardiac tissue apoptosis. In addition, Oxfenicine promotes lipolysis in a high-fat diet rat model. Oxfenicine can be used in the study of cardiovascular and metabolic diseases .
Cat. No.: HY-W015924
CAS No.: 594-61-6
Target:
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Animals Anti-aging Metabolic Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-124529
CAS No.: 37116-80-6
Category:
Human Gut Microbiota Metabolites other families Conocephalum conicum (L.) Dumort. Phenols Polyphenols Plants Endogenous metabolite
Target:
Cat. No.: HY-W096638A
CAS No.: 4217-84-9
Synonyms: (S)-Glycerolphosphocholine
Target:
Cat. No.: HY-W012974
CAS No.: 144-90-1
Synonyms: β-Aminoisobutyric acid; BAIBA
Category:
Cardiovascular Disease Ketones, Aldehydes, Acids Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
Target:
Research Areas:
Sodium Tartrate (E335ii) is an approved food additive that functions as both a pH regulator and an emulsifier. Sodium Tartrate effectively inhibits hydrolysis, thermal oxidation, polymerization and coloration of vegetable oil during high-temperature heating, exhibiting significant antioxidant activity. The DL-tartaric acid component of Sodium Tartrate has an absorption rate of up to 90% in brown rats, while the absorption rate of related tartaric acid in humans is only 20% .
Cat. No.: HY-123033AR
CAS No.: 23111-00-4
Category:
Cat. No.: HY-14811
CAS No.: 251111-30-5
Synonyms: ZGN-440; CKD-732 free base
Research Areas:
Beloranib (ZGN-440; CKD-732 free base) is a selective, irreversible inhibitor of methionine aminopeptidase MetAP2 that suppresses appetite and increases energy expenditure. Beloranib blocks the enzymatic cleavage of N-terminal methionine from nascent proteins by forming a covalent bond with MetAP2, thereby regulating fatty acid metabolism, adrenergic signaling, and hypothalamic NF-κB expression. Beloranib significantly reduces food intake, body weight, and fat accumulation, while improving glucose tolerance, insulin sensitivity, and lipid metabolism. Beloranib also elevates energy expenditure and fat oxidation levels, without affecting body temperature, spontaneous activity, or the inflammatory cytokine IL-1β. Beloranib can be used in research on obesity and hypothalamic obesity .
Target:
Research Areas:
Phenylcapsaicin is an analogue of Capsaicin (HY-10448). Phenylcapsaicin is a TRPV1 receptor activator. Phenylcapsaicin enhances fat oxidation during aerobic exercise .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
