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Results for "

fluorescent proteins

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Fluorescent Dye (352) Amino Acid Derivatives (3) Amyloid-β (3) Apoptosis (2) Arf Family GTPase (1) Autophagy (2) Bacterial (3) Bcl-2 Family (1) Beta-secretase (1) Biochemical Assay Reagents (114) Carboxylesterase (CES) (1) Caspase (1) Deubiquitinase (1) DNA Stain (3) DNA/RNA Synthesis (1) Drug Derivative (2) Drug Intermediate (4) Drug Isomer (1) Drug Metabolite (1) E1/E2/E3 Enzyme (1) EGFR (2) Endogenous Metabolite (1) Environmental Pollutants (1) Estrogen Receptor/ERR (2) FABP (1) FAP (3) Fungal (1) Glutamate Dehydrogenase (GLDH) (2) Glycosidase (1) Huntingtin (2) Isotope-Labeled Compounds (2) Ligands for E3 Ligase (1) Liposome (6) MAGL (1) Microtubule/Tubulin (1) Mitochondrial Metabolism (2) MOFs (1) mRNA (13) NF-κB (1) Nucleoside Antimetabolite/Analog (1) Oxidative Phosphorylation (1) Parasite (4) PARP (1) Phosphatase (2) Phosphodiesterase (PDE) (2) Phospholipase (1) PKC (3) PPAR (1) Prolyl Endopeptidase (PREP) (1) PROTACs (1) Reactive Oxygen Species (ROS) (1) Reference Standards (2) SHP1 (1) Smo (1) Transthyretin (TTR) (1) TSPO (1) β-catenin (1)
By Research Areas:	Cancer (25) Cardiovascular Disease (1) Infection (9) Inflammation/Immunology (7) Metabolic Disease (6) Neurological Disease (10)
Click Chemistry:	TCO (1) Labeling and Fluorescence Imaging (8) DBCO (3) Azide (7) Tetrazine (1) Alkynes (6)
Oligonucleotides:	Pegylated Lipids (1) Aptamers (2) Liposome (4) Cationic Lipids (1) mRNA (14) Reporter Genes (7) Cholesterol (1) Gene Editing (4)

510

Inhibitors & Agonists

322

Fluorescent Dyes

108

Biochemical Assay Reagents

Peptides

MCE Kits

Natural
Products

Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Targets Recommended: Fluorescent Dye Slit Proteins Synaptic Vesicle Proteins HSP YTHDF

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0974

Sulforhodamine B sodium salt 5+ Cited Publications Acid Red 52; Kiton Red 620	Environmental Pollutants Fluorescent Dye	Others
Sulforhodamine B sodium salt is a fluorescent dye with uses spanning from laser-induced fluorescence (LIF) to the quantification of cellular proteins of cultured cells.

HY-D0822

CY3 4 Publications Verification Sulfo-Cyanine3	Fluorescent Dye	Others
Cy3 (Sulfo-Cyanine3) is an orange-fluorescent label for protein and nucleic acid (λ_ex=554, λ_em=568).

HY-15944

5(6)-TAMRA 3 Publications Verification 5(6)-Carboxytetramethylrhodamine	Fluorescent Dye	Others
5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).

HY-135414

Cyanine5 NHS ester chloride 1 Publications Verification	Fluorescent Dye	Others
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-15938

5-FAM SE	Fluorescent Dye	Others
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .

HY-D0896

ANS 1 Publications Verification ANSA; 8-Anilino-1-naphthalenesulfonic acid	Bacterial	Infection
ANS (8-Anilino-1-naphthalenesulfonic acid) is a competitive inhibitor targeting thyroxine binding globulin (TBG) (K_i=2.09×10 ⁶ M ^-1). ANS is used in radioimmunoassay by displacing bound triiodothyronine (T3) to improve detection sensitivity. ANS can block the protein binding site of T3 and release free T3 for antibody recognition. As a fluorescent probe, ANS can specifically bind to the hydrophobic region of proteins (such as membrane proteins) and monitor the dynamics of protein conformation through changes in fluorescent signals. It is widely used in biochemical research and antibacterial material development .

HY-130533

ReAsH-EDT2	Fluorescent Dye	Others
ReAsH-EDT2 is a red fluorescent dye that marks proteins. ReAsH-EDT2 is a membrane-permeable biarsenical compound that binds covalently to tetracysteine sequences which allows the protein to be imaged. ReAsH-EDT2 can be used for protein localization and trafficking. (λ_ex=530 nm, λ_em=592 nm) .

HY-15937

5(6)-FAM SE 4 Publications Verification 5(6)-Carboxyfluorescein N-hydroxysuccinimide ester; 5(6)-Carboxyfluorescein succinimidyl ester mixed isomers	Fluorescent Dye	Others
5(6)-FAM SE is a green fluorescent dye widely used for protein labeling.

HY-110250

DFHBI 5+ Cited Publications	Fluorescent Dye	Others
DFHBI is a small molecule that resembles the chromophore of green fluorescent protein (GFP). DFHBI can be used for imaging RNA in living cells. . Spinach and DFHBI are essentially nonfluorescent when unbound, whereas the Spinach-DFHBI complex is brightly fluorescent both in vitro and in living cells (Ex/Em = 469/501 nm).

HY-D1819

Vari Fluor 633-Phalloidin	Fluorescent Dye	Others
Vari Fluor 633-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence at 630/650 nm when labeled .

HY-D1314

FAM azide, 6-isomer 6-FAM azide	Fluorescent Dye	Others
FAM azide, 6-isomer (6-FAM azide) is a 6-carboxyfluorescein derivative with an azide functional group and coupling partner in copper-catalyzed azide-alkyne cycloaddition. FAM azide, 6-isomer participates in synthesis of fluorescently tagged disparlure enantiomers for pheromone-binding protein binding assays. FAM azide, 6-isomer is widely used for labeling oligonucleotides (Ex/Em = 493/517 nm) .

HY-D0807

5-IAF 1 Publications Verification 5-Iodoacetamidofluorescein	Fluorescent Dye	Cancer
5-IAF (5-Iodoacetamidofluorescein) is an idoacetamide derivate of fluoresceine. 5-IAF can be used as fluorescent probe that labels proteins and other molecules having free thiols (cysteine side chains) .

HY-D1506

Fl-DIBO	Fluorescent Dye	Others
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P2528

*Enhanced Green Fluorescent* Protein (EGFP) (200-208)**	Fluorescent Dye	Others
Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria. Enhanced Green Fluorescent Protein (EGFP) (200-208) is a common reporter protein and is easy to detect .

HY-D1849

Cy3B NHS ester	Fluorescent Dye	Others
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.

HY-D1605

BODIPY FL L-Cystine 1 Publications Verification	Fluorescent Dye	Others
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λ_ex=504 nm, λ_em=511 nm) .

HY-124171

Zinquin ethyl ester 1 Publications Verification	Fluorescent Dye Drug Derivative	Others
Zinquin ethyl ester is a cell-permeable and lipophilic fluorescent derivative of Zinquin (HY-D0982). Zinquin ethyl ester reacts with protein-bound Zn ²⁺ in cells and forms fluorescent ternary adducts. Zinquin ethyl ester undergoes hydrolysis by intracellular esterases impeding its efflux across the plasma membrane (Ex/Em = 370/470 nm) .

HY-W998680

Fluorescein-maleimide 5-FITC-Maleimide	Fluorescent Dye	Others
Fluorescein-maleimide (5-FITC-Maleimide) is a thiol-reactive fluorescent derivatization reagent and non-specific protein labeling reagent. Fluorescein-maleimide covalently binds to protein thiol groups for protein labeling. Fluorescein-maleimide covalently binds to protein amino and imidazole groups under neutral pH conditions. Fluorescein-maleimide is used for fluorescent labeling of proteins, nucleic acids or other molecules containing one or more thiol groups (Ex/Em = 494/519 nm) .

HY-W015590

2-Hydroxyphenylacetic acid	Drug Metabolite Fungal	Infection Metabolic Disease
2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia .

HY-D0077

2',7'-Difluorofluorescein Oregon green 488	Fluorescent Dye	Others
2',7'-Difluorofluorescein (Oregon green 488) is a fluorescein derivative and a pH-sensitive fluorescent probe (pK_a ~4.7). Upon excitation at 488 nm, 2',7'-Difluorofluorescein exhibits pH-sensitive fluorescence intensity through the formation of dianions, while its pH sensitivity decreases under excitation at 450 nm, allowing its use in ratiometric pH analysis. 2',7'-Difluorofluorescein can be used for the quantitative analysis of pH values in the range of 2-7 in submicron aerosol particles. 2',7'-Difluorofluorescein undergoes buffer-mediated and buffer-free excited-state proton transfer between different protonated forms, and its cationic form undergoes rapid excited-state deprotonation. 2',7'-Difluorofluorescein is resistant to photodegradation, maintains stable absorption and fluorescence properties within the physiological pH range, and serves as a fluorescent protein label, a component of Ca ²⁺ indicators, a fluorescent imaging agent, and an anisotropy probe .

HY-143702

Fluorescent DOTAP NBD-DOTAP	Fluorescent Dye Liposome	Inflammation/Immunology Cancer
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .

HY-D1781

NTPAN-MI	Fluorescent Dye	Others
NTPAN-MI is a fluorescent probe (excitation wavelength: 405 nm). NTPAN-MI is selectively activated after labeling unfolded proteins with exposed thiols, thereby reporting the degree of protein homeostasis .

HY-W273413

4-Hydrazino-7-nitro-benzofurazan hydrazine adduct NBD-H	Fluorescent Dye	Cancer
4-Hydrazino-7-nitro-benzofurazan hydrazine adduct (NBD-H) is a fluorescent reagent used for protein labeling .

HY-153232

eGFP circRNA-LNP	Fluorescent Dye Liposome	Others
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .

HY-120959

DAUDA	Fluorescent Dye Parasite	Others
DAUDA (11-(dansylamino) undecanoic acid) is an environment-sensitive fluorescent fatty acid analogue. DAUDA alters its intensities and fluorescent emission spectra on entry into binding proteins. DAUDA is used to determine the relative affinity of natural fatty acids for polymorphs of the Schistosoma mansoni Sm14 fatty acid-binding protein[1].

HY-141667

MBD 7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole	Fluorescent Dye	Others
MBD (7-(p-Methoxybenzylamino)-4-nitrobenz-2,1,3-oxadiazole), a new fluorescent probe for protein and nucleoprotein conformation, is applied to bacterial ribosomes and to bovine trypsinogen and trypsin. MBD is strongly fluorescent upon binding to a hydrophobic area of a macromolecule .

HY-D1820

Vari Fluor 594-Phalloidin 1 Publications Verification	Fluorescent Dye	Others
Vari Fluor 594-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence at 585/609 nm when labeled .

HY-D1443

BSB (trans,trans)-1-Bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene	Amyloid-β	Others
BSB is a Congo red-derived fluorescent probe. BSB binds not only to extracellular amyloid β protein, but also many intracellular lesions composed of abnormal tau and synuclein proteins. BSB acts as a prototype imaging agent for Alzheimer's disease .

HY-D0941

5-Carboxytetramethylrhodamine 1 Publications Verification	Fluorescent Dye	Others
5-Carboxytetramethylrhodamine can be used as a fluorescent probe of nucleic acids and proteins. 5-Carboxytetramethylrhodamine displays excitation maxima of 558 nm and an emission maximum of 586 nm .

HY-124197

Coumarin hydrazine	Fluorescent Dye	Others
Coumarin hydrazine is a fluorescent chemical probe (λ_ex=420–450/λ_em=468nm) to label cellular protein- and lipid-bound carbonyls .

HY-151776

Cy3 methyltetrazine TZ-Cy3	Fluorescent Dye	Others
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a *tetrazine-modified fluorescent* probe** that can be used to analyze protein phosphorylation in solution and living cells .

HY-171493

mCherry mRNA(N1-Me-Pseudo UTP)	Biochemical Assay Reagents	Others
mCherry mRNA(N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression analysis, cell viability assays, and in vivo imaging. mCherry, derived from mushroom coral, is a widely used red fluorescent protein tracer in biotechnology applications.

HY-155640

5-FAM maleimide	Fluorescent Dye	Others
Maleimide-5’FAM is a fluorescein. Maleimide-5’FAM can be used for labeling non-transduced cells .

HY-D0099

Fluorescein-5-thiosemicarbazide	Fluorescent Dye	Others
Fluorescein-5-thiosemicarbazide is a amine containing fluorescent probe that can be used for labeling saccharides and protein carbonyl derivatives .

HY-110211

BODIPY TMR-X SE	Fluorescent Dye	Others
BODIPY TMR-X SE is a potent fluorescent dye. BODIPY TMR-X SE can be used to label the primary amines (R-NH₂) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. BODIPY TR-X binds to protein or antibody and has bright, orange fluorescent light. (λ_ex=544 nm, λ_em=570 nm) .

HY-153231A

eGFP mRNA-LNP (500 ng/μL)	Fluorescent Dye Liposome	Others
eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .

HY-D1327

Cyanine3 azide chloride 1 Publications Verification	Fluorescent Dye	Others
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm) ^[1]. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-D1342

Coumberol	Fluorescent Dye	Cancer
Coumberol is a fluorescent substrate of AKR1C3 protein. Coumberol can be used for the research of AKR1C3 .

HY-147889

BBR-BODIPY	Apoptosis Caspase Bcl-2 Family	Others
BBR-BODIPY is a fluorescent probe that allows screening its interaction with the targeted cells. BBR-BODIPY induces apoptosis and changes the expression of apoptosis-related proteins .

HY-D1818

Vari Fluor 680-Phalloidin	Fluorescent Dye	Others
Vari Fluor 680-Phalloidin is a fluorescent derivative of Phalloidin that specifically labels myofilament proteins and exhibits red fluorescence when labeled at 680/700 nm .

HY-D2498

Cy7 maleimide	Fluorescent Dye	Others
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .

HY-D1692

BODIPY 650/665 NHS ester	Fluorescent Dye	Others
BODIPY 650/665 NHS ester is bright, far-red fluorescent dye that can be used to label the primary amines (R-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules . Ex / Em = 646 / 660 nm

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dye	Others
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-137100

Cy 5 hydrazide Cyanine5 hydrazide	Fluorescent Dye	Others
Cy 5 hydrazide (Cyanine5 hydrazide) is a fluorescent dye for aldehydes and ketones. Cy 5 hydrazide can be used for labeling proteins .

HY-D2444

AF555 NHS	Fluorescent Dye	Cancer
AF555 NHS is a red fluorescent dye with excellent fluorescence properties and light stability. The excitation wavelength is 556 nm and the emission wavelength is 571 nm, which can be used for protein labeling, antibody labeling, and cell imaging .

HY-145385

Coelenteramide	Fluorescent Dye	Others
Coelenteramide is a oxidative product of Coelenterazine (HY-18743). Coelenteramide can form a complex with apoAequorin/Ca ²⁺, which is known as blue fluorescent protein (BFP) and shows continuous weak luminescence with Coelenterazine like a luciferase. Coelenteramide can be used as an imaging agent .

HY-174795

mCherry mRNA	mRNA	Others
mCherry mRNA encodes the mCherry fluorescent protein, which is derived from Anaplasma marginale. mCherry can be used as a fluorescent tracer in transfection and transgenic experiments or as a reporter of gene expression.

HY-D0968

Cy 3 (Non-Sulfonated) Cyanine3	Fluorescent Dye	Others
Cy 3 Non-Sulfonated (Cyanine3) is a fluorescent label for protein and nucleic acid.

HY-174789

Gaussia luciferase mRNA	mRNA	Others
Gaussia luciferase (GLuc) mRNA will express a luciferase protein, derived from the Gaussia princeps. luciferases are widely used in biotechnology, for microscopy and as reporter genes, for many of the same applications as fluorescent proteins.

HY-D2377

F8	Fluorescent Dye	Others
F8 is a small molecule GPR84 fluorescent probe that can visualize and detect GPR84 protein levels at the cellular and tissue levels .

Cat. No.	Product Name	Target	Research Area

HY-P2528

*Enhanced Green Fluorescent* Protein (EGFP) (200-208)**	Fluorescent Dye	Others
Enhanced Green Fluorescent Protein (EGFP) (200-208) is a marker gene product derived from the jellyfish Aequorea Victoria. Enhanced Green Fluorescent Protein (EGFP) (200-208) is a common reporter protein and is easy to detect .

HY-P0327

T7 Tag Peptide 1 Publications Verification	Peptides	Others
T7 Tag Peptide is a protein tag peptide composed of 11 residues from the N-terminus of gp10, the capsid protein of T7 bacteriophage. T7 Tag Peptide can be fused to the N-terminus or C-terminus of proteins such as enhanced green fluorescent protein (EGFP). T7 Tag Peptide is applicable for various immunoassays and affinity purification .

HY-P5481

DABCYL-LPETG-EDANS	Peptides	Others
DABCYL-LPETG-EDANS is a biological active peptide. (This 5-amino acid peptide is a sortase substrate, C-terminal sorting signal. Sortase cleaves surface proteins at the LPXTG motif and catalyzes the formation of an amide bond between the carboxyl group of threonine and the amino group of cell-wall crossbridges. Sortases are a family of Gram-positive transpeptidases responsible for anchoring surface protein virulence factors to the peptidoglycan cell wall layer. Cleavage of this FRET substrate by sortase reveals the fluorescent signal, Abs/Em = 340/490 nm.)

HY-P10680

TFE-IDAtp1-LinA	Liposome	Others
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED₅₀ of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .

HY-P10615

Abz-YGGRASDQ-EDDnp	Fluorescent Dye Transthyretin (TTR)	Others
Abz-YGGRASDQ-EDDnp is a fluorescent substrate of transthyretin (TTR) protein and is used to detect the hydrolytic activity of TTR protein .

HY-P10317

Suc-YVAD-AMC	Fluorescent Dye	Others
Suc-YVAD-AMC is used to measure the cysteine proteins of the proteasome.Suc-YVAD-AMC releases fluorescent AMC when cleaved by cysteine proteases to assess the enzymatic activity of the proteasome .

HY-P0327A

T7 Tag Peptide TFA 1 Publications Verification	Peptides	Others
T7 Tag Peptide TFA is a protein tag consisting of 11 residues from the N-terminus of the T7 bacteriophage capsid protein gp10. T7 Tag Peptide TFA can be fused to the N-terminus or C-terminus of proteins such as enhanced green fluorescent protein (EGFP). T7 Tag Peptide TFA can be used in various immunoassays and affinity purification .

HY-P4919

Mca-SEVNLDAEFK(Dnp)	Beta-secretase	Others
Mca-SEVNLDAEFK(Dnp) is a Beta-secretase 1 (BACE-1) peptide FRET substrate, containing the 'Swedish' Lys-Met/Asn-Leu mutation of the amyloid precursor protein (APP) β-secretase cleavage site. Cleavage at -Leu-Asp- of Mca-SEVNLDAEFK(Dnp) liberates the highly fluorescent 7-methoxycoumarin (Mca) fragment from the proximity quenching effect of the 2,4-dinitrophenyl (Dnp) internal quencher resulting in a large and easily detectable increase in fluorescence intensity.

HY-P4878

5-TAMRA-Amyloid β-Protein (1-40)	Amyloid-β	Neurological Disease
5-TAMRA-*Amyloid β-Protein* (1-40)** is a fluorescent (TAMRA)-labeled Amyloid β-Protein (1-40), Abs/Em=544/572 nm .

HY-P11757

Cyclo[K(N3)larllt]	EGFR	Cancer
Cyclo[K(N3)larllt] is a seven-membered cyclic peptide targeting EGFR, with a K_d value of 5.09 μM, and exhibits binding selectivity toward homologous proteins HER2 and HER3. Cyclo[K(N3)larllt] has no cytotoxicity and shows no growth inhibitory effect on cancer cells overexpressing EGFR. Cyclo[K(N3)larllt] can serve as a ligand for EGFR-targeted fluorescent conjugates, which is applicable to the detection of cancers with EGFR overexpression. Cyclo[K(N3)larllt] can be used in the research of colorectal cancer .

Cat. No.	Product Name

HY-KD1103

Red Fluorescent Rapid Labeling Kit (CY3）

Red Fluorescent Rapid Labelling Kit (CY3) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 550/570 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, one IgG molecule can bind 2–8 molecules of CY3. The entire experiment can be completed within 2 hours.

HY-KD1101

Green Fluorescent Rapid Labeling Kit (FITC）

Green Fluorescent Rapid Labelling Kit (FITC) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 488/515 nm. Based on NHS-ester chemistry, the NHS-ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of FITC. The entire procedure can be completed within two hours.

HY-KD1106

Deep Red Fluorescent Rapid Labeling Kit (AF647）

Red Fluorescent Rapid Labelling Kit (AF647) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 647/665 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF647. The entire procedure can be completed within two hours.

HY-KD1107

Deep Red Fluorescent Rapid Labeling Kit (CY5）

Deep Red Fluorescent Rapid Labelling Kit (CY5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 649/667 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY5. The entire experiment can be completed within 2 hours.

HY-KD1111

NIR Red Fluorescent Rapid Labeling Kit (AF750）

Near-infrared Fluorescent Rapid Labelling Kit (AF750) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 750/775 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF750. The entire procedure can be completed within two hours.

HY-KD1102

Green Fluorescent Rapid Labeling Kit (AF488）

Green Fluorescent Rapid Labelling Kit (AF488) enables green fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 480/525 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF488. The entire procedure can be completed within two hours.

HY-KD1105

Red Fluorescent Rapid Labeling Kit (AF594）

Red Fluorescent Rapid Labelling Kit (AF594) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 594/617 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds, thereby achieving conjugation with antibodies/proteins. Typically, one IgG molecule can bind 2-8 molecules of AF594. The entire procedure can be completed within two hours.

HY-KD1104

Red Fluorescent Rapid Labeling Kit (AF555）

Red Fluorescent Rapid Labelling Kit (AF555) enables red fluorescent labelling of proteins. Maximum excitation/ Emission Wavelength: 555/565 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in pH 7-9 solutions to form stable amide bonds with the target antibody/protein, achieving conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF555. The entire procedure can be completed within two hours.

HY-KD1109

NIR Red Fluorescent Rapid Labeling Kit (CY7）

Near-infrared Fluorescent Rapid Labelling Kit (CY7) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 750/773 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2–8 molecules of CY7. The entire experiment can be completed within 2 hours.

HY-KD1108

Deep Red Fluorescent Rapid Labeling Kit (CY5.5）

Deep Red Fluorescent Rapid Labelling Kit (CY5.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 678/695 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY5.5. The entire procedure can be completed within two hours.

HY-KD1112

Blue Fluorescent Rapid Labeling Kit (AF350）

TheBlue Fluorescence Rapid Labelling Kit (AF350) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 346/442 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of AF350. The entire procedure can be completed within two hours.

HY-KD1110

NIR Red Fluorescent Rapid Labeling Kit (CY7.5）

The Near-Infrared Fluorescence Rapid Labelling Kit (CY7.5) enables red fluorescent labelling of proteins. Maximum excitation/ emission wavelengths: 788/814 nm. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled at pH 7-9, forming stable amide bonds to achieve conjugation. Typically, one IgG molecule can bind 2-8 molecules of CY7.5. The entire procedure can be completed within two hours.

HY-KD1113

Biotinylated Rapid Labeling Kit

The Biotinylation Rapid Labelling Kit enables biotinylation of proteins. Based on NHS ester chemistry, the NHS ester-activated fluorescent dye reacts with primary amines in the antibody/protein to be labelled within a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2-8 molecules of biotin. The entire procedure can be completed within two hours.

HY-KD1115

DOTA Rapid Labeling Kit

The DOTA rapid labelling kit enables DOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to form stable amide bonds at pH 7–9, thereby achieving conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 DOTA molecules. The entire procedure can be completed within 2 hours.

HY-KD1114

Nota Rapid Labeling Kit

The NOTA Rapid Labelling Kit enables NOTA labelling of proteins. Based on NHS ester chemistry, NHS ester-activated fluorescent dyes react with primary amines on the antibody/protein to be labelled in a pH 7-9 solution, forming stable amide bonds to achieve conjugation with the antibody/protein. Typically, a single IgG molecule can bind 2–8 NOTA molecules. The entire procedure can be completed within two hours.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W015590

2-Hydroxyphenylacetic acid	Structural Classification Monophenols Ketones, Aldehydes, Acids Disease markers Phenols Endocrine diseases Nervous System Disorder Endogenous metabolite Source Classification	Drug Metabolite Fungal
2-Hydroxyphenylacetic acid is a metabolite of Phenylalanine and Tyrosine, as well as a product of the biotransformation of Phenylacetonitrile by marine fungi. 2-Hydroxyphenylacetic acid acts as a potential biomarker for food. 2-Hydroxyphenylacetic acid slightly induces the expression of green fluorescent protein. 2-Hydroxyphenylacetic acid is used in the research of phenylketonuria and related hyperphenylalaninemia .

HY-113033

Pentosidine	Structural Classification Natural Products Disease markers Endogenous metabolite Source Classification	Others Biochemical Assay Reagents
Pentosidine is a fluorescent advanced glycation end product (AGE) and cross-linker. Pentosidine is a fluorescent cross-linked structure formed by lysine and arginine in sugar oxidation reactions, and it is commonly found in collagen, skin, bone, lens and plasma proteins . Pentosidine is used in research related to type 1 diabetes, brown cataracts, rheumatoid arthritis, atherosclerosis and neurodegenerative diseases .

HY-N16309

Cyanine 7 free acid bromide	Lipid	Fluorescent Dye
Cyanine 7 free acid bromide is a near-infrared fluorescent probe for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry.

HY-129330

Sapintoxin D	Natural Products Euphorbiaceae Shirakiopsis indica (Willd.) Esser Plants Source Classification	PKC
Sapintoxin D is a fluorescent phorbol ester that can be used to study the activation of protein kinase C (PKC). Sapintoxin D is a calcium-dependent PKC activator .

HY-165424

NIR-BG2	Alkaloids Other Alkaloids Cananga odorata Plants Annonaceae Indole Alkaloids Source Classification	Fluorescent Dye Glycosidase
NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence .

HY-D1365B

Sulfo-Cy3(Me)COOH potassium	Lipid	Fluorescent Dye
Sulfo-Cyanine 3 free acid potassium is a sulfo-Cyanine3 derivative. Cyanine3 is an orange-fluorescent label dye for protein and nucleic acid (Ex=554 nm, Em=568 nm) .

HY-N15885

12-NBD Stearate	Lipid	Fluorescent Dye FABP Phosphatase
12-NBD Stearate is a fluorescent fatty acid analogue. 12-NBD Stearate binds to fatty acid binding protein (FABP) and sterol carrier protein-2 (SCP-2). Overexpressing sterol carrier protein-2 (SCP-2) 15-kDa isoform enhances 12-NBD Stearate transport. 12-NBD Stearate is a tool for microscopic long chain fatty acids (LCFA) uptake and internalization studies .

HY-N16316

Meso-Cl cyanine 7 free acid chloride	Lipid	Fluorescent Dye
Meso-Cl cyanine 7 free acid chloride is a Meso-Cl cyanine fluorescent dye. Meso-Cl cyanine 7 free acid chloride can be used for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry (Ex/Em = 778/805 nm) .

HY-N16307

Meso-Cl cyanine 7.5 free acid chloride	Lipid	Fluorescent Dye
Meso-Cl cyanine 7.5 free acid chloride is a Meso-Cl cyanine fluorescent dye. Meso-Cl cyanine 7.5 free acid chloride can be used for labelling amine groups such as those on antibodies, nucleic acids, and proteins and can be detected using a variety of fluorescence detection techniques such as microscopy and flow cytometry (Ex/Em = 815/825 nm) .

Cat. No.	Product Name	Chemical Structure

HY-D0017S

Dansyl chloride-d6
Dansyl chloride-d₆ is the deuterium labeled Dansyl chloride (HY-D0017). Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-124197S

Coumarin hydrazine-d7
Coumarin hydrazine-d₇ is the deuterium labeled Coumarin hydrazine (HY-124197). Coumarin hydrazine is a fluorescent chemical probe (λex=420–450/λem=468nm) to label cellular protein- and lipid-bound carbonyls .

HY-D0017S1

Dansyl chloride-13C2
Dansyl chloride- ¹³C₂ is the ¹³C labeled Dansyl chloride (HY-D0017) . Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis.

Cat. No.	Product Name		Classification

HY-164745

L-β-Ethynylserine		Alkynes
L-β-ethynylserine (βES) is a threonine analog. L-β-ethynylserine is efficiently incorporated into newly synthesized proteins, and allows their selective visualization or enrichment through bioorthogonal ligation to fluorescent dyes or affinity tags, respectively .

HY-D1314

FAM azide, 6-isomer 6-FAM azide		Labeling and Fluorescence Imaging Azide
FAM azide, 6-isomer (6-FAM azide) is a 6-carboxyfluorescein derivative with an azide functional group and coupling partner in copper-catalyzed azide-alkyne cycloaddition. FAM azide, 6-isomer participates in synthesis of fluorescently tagged disparlure enantiomers for pheromone-binding protein binding assays. FAM azide, 6-isomer is widely used for labeling oligonucleotides (Ex/Em = 493/517 nm) .

HY-D1506

Fl-DIBO		Labeling and Fluorescence Imaging
Fl-DIBO (fluorogenic dibenzocyclooctyne) is a selective and high sensitivity fluorescent probe to azide compounds. Fl-DIBO can react rapidly with azide compounds to form new highly fluorescent products with a maximum emission wavelength of 469 nm and excitation wavelength of 363 nm. Fl-DIBO can be used to label diazo-tagged proteins without detectable background signal interference . Fl-DIBO is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-D1051

Cy3-N3		Azide Labeling and Fluorescence Imaging
Cy3-N3 is a Cy3-azide fluorescent dye used to label for protein and nucleic acid. Cy3-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em = 548/563 nm).

HY-W039953

Ac4GlcNAz N-azidoacetylglucosamine-tetraacylated		Azide
Ac4GlcNAz (N-azidoacetylglucosamine-tetraacylated) is an azido-tagged analogue of N-acetylglucosamine (GlcNAC). It features azide functionality on the N-acyl side chain and is acetylated to aid in cell membrane permeation. Once in the cell, the acetylated compound is deprotected and takes part in the hexosamine biosynthetic pathway by action of GlcNAc kinase. The resulting modified proteins are detected by the addition of fluorescent tags under Cu(I)-catalyzed azide-alkyne cycloaddition conditions.

HY-137042

Cyanine5 alkyne Alkyne-Cy5		Alkynes Labeling and Fluorescence Imaging
Cyanine5 alkyne (Alkyne-Cy5) is a fluorescent dye used to label azide proteins and can be used to analyse post-translational modifications of proteins, glycosylation etc. Cyanine5 alkyne can also be used as a mitochondrial OXPHOS inhibitor to inhibit the growth of cancer stem cells (CSC) . Cyanine5 alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-151776

Cy3 methyltetrazine TZ-Cy3		Labeling and Fluorescence Imaging Tetrazine
Cy3 methyltetrazine (TZ-Cy3) is a click chemistry reagent with methyltetrazine building blocks that is highly reactive towards cyclooctene. Cy3 methyltetrazine is also a *tetrazine-modified fluorescent* probe** that can be used to analyze protein phosphorylation in solution and living cells .

HY-D2443

AF594 DBCO		DBCO
AF594 DBCO is an AlexaFluor 594-conjugated DBCO click chemistry probe for fluorescent labeling of azido-modified cholesterol probes. DBCO is a commonly used chemical biomarker group. AF594 DBCO (Excitation wavelength about 590 nm, emission wavelength about 617 nm) can be used to label proteins, cells and other biomolecules for fluorescence imaging and flow cytometry detection .

HY-D1327

Cyanine3 azide chloride 1 Publications Verification		Labeling and Fluorescence Imaging Azide
Cyanine3 azide chloride, an analog of Cy3 azide, is a potent green fluorescent dye. Cyanine3 azide chloride uses click chemistry coupled with Alkyne-labeled proteins. Cyanine3 azide chloride can be detected by fluorometers, imagers, and microscopes. (λ_ex=684 nm, λ_em=710 nm) ^[1]. Cyanine3 azide (chloride) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-151759

Sulfo-Cy5-TCO		TCO Labeling and Fluorescence Imaging
Sulfo-Cy5-TCO is a water-soluble sulfonated Cy5 fluorescent reagent containing trans-cyclooctene (TCO). Sulfo-Cy5-TCO undergoes an inverse electron demand Diels‑Alder reaction with tetrazine-labeled fixed breast cancer cells to achieve cell labeling. Sulfo-Cy5-TCO is used for fluorescent labeling and imaging of biological samples such as proteins and cells .

HY-D2891

5-TAMRA-DBCO		DBCO
5-TAMRA-DBCO is a fluorescent dye that combines 5-TAMRA (HY-15942) with a dibenzocyclooctyne (DBCO) moiety. 5-TAMRA-DBCO is able to copper-free click chemistry reactions with azide-functionalized molecules. 5-TAMRA-DBCO can be used for labeling proteins, peptides, nucleic acids (Ex/Em = 541/567 nm) .

HY-P10680

TFE-IDAtp1-LinA		Azide
TFE-IDAtp1-LinA is a highly potent amphiphilic carrier, containing a trifluoroethyl-iminodiacetic acid analog of Stp. TFE-IDAtp1-LinA, formed nanoparticles with Cas9 RNP/ssDNA, achieved enhanced green fluorescent protein knockouts with an ED₅₀ of 0.38 nM Cas9/sgRNA ribonucleoproteins (RNP) .

HY-D1860

Cy3 alkyne chloride		Alkynes
Cy3 alkyne chloride is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing a sulfonate ion and an alkyne functional group. Cy3 is a fluorescent dye with a fluorescence spectrum typically in the green to orange wavelength range. The alkyne functional group of Cy3 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy3 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-W879234

TriSulfo-Cy5.5 DBCO Sulfo Cy5.5-DBCO		DBCO
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.

HY-151756

diSulfo-Cy3 alkyne		Alkynes Labeling and Fluorescence Imaging
diSulfo-Cy3 alkyne is a water-soluble dye and a Click Chemistry reagent containing an alkyne group. Absorbance and emission of the dye are identical to Cy3 fluorophore. diSulfo-Cy3 alkyne can be used for the labeling of proteins, and even intact biological objects in water phase .

HY-D1862

Cy7.5 alkyne chloride		Alkynes
Cy7.5 alkyne chloride is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functional group of Cy7.5 alkyne chloride can react with molecules containing the azide functional group to form covalent bonds. Cy7.5 alkyne chloride can bind to biological molecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-D1859

Sulfo-Cy7.5 alkyne		Alkynes
Sulfo-Cy7.5 alkyne is a dye derivative of Cyanine 7.5 (Cy7.5) (HY-D0926) containing a sulfonate ion and an alkyne functional group. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The alkyne functionality of Sulfo-Cy7.5 alkyne can react with molecules containing the azide functionality to form covalent bonds. Sulfo-Cy7.5 alkyne can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples.

HY-D1850

Sulfo-Cy7.5 azide		Azide
Sulfo-Cy7.5 azide is a Cyanine 7.5 (Cy7.5) (HY-D0926) dye derivative with azide and sulfonate functional groups. The sulfonate ion increases the water solubility of the compound, making it suitable for use in aqueous solutions. Cy7.5 is a near-infrared fluorescent dye commonly used for biolabeling and cell imaging. The azide group of Sulfo-Cy7.5 azide can react chemically with molecules containing alkyne functionality, such as alkyne or cyclooctyne, to form covalent bonds. Therefore, Sulfo-Cy7.5 azide can bind to biomolecules such as proteins and antibodies to track their location and dynamic changes in biological samples. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.

HY-P11757

Cyclo[K(N3)larllt]		Azide
Cyclo[K(N3)larllt] is a seven-membered cyclic peptide targeting EGFR, with a K_d value of 5.09 μM, and exhibits binding selectivity toward homologous proteins HER2 and HER3. Cyclo[K(N3)larllt] has no cytotoxicity and shows no growth inhibitory effect on cancer cells overexpressing EGFR. Cyclo[K(N3)larllt] can serve as a ligand for EGFR-targeted fluorescent conjugates, which is applicable to the detection of cancers with EGFR overexpression. Cyclo[K(N3)larllt] can be used in the research of colorectal cancer .

Cat. No.	Product Name		Classification

HY-153079

eGFP mRNA (N1-Me-Pseudo UTP)		mRNA
eGFP mRNA (N1-Me-Pseudo UTP) will express green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. The eGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with N1-Me-Pseudo UTP (m1Ψ) improves protein expression and reduces innate immune response.

HY-174497

eGFP mRNA		mRNA Reporter Genes
eGFP mRNA expresses green fluorescent protein derived from the jellyfish Aequorea victoria. eGFP is a commonly used direct-detection reporter gene in mammalian cell culture, which produces bright green fluorescence. This product is synthesized without modified nucleosides, with a Cap1 version cap analog at the 5' end and a 100nt PolyA tail at the 3' end. It can be used as a positive reference for IVT (in vitro transcription) or LNP delivery systems.

HY-153229

Firefly luciferase mRNA-LNP 1 Publications Verification		mRNA Liposome
Firefly luciferase mRNA-LNP is a lipid nanoparticle (LNP) containing firefly luciferase mRNA. Firefly luciferase mRNA-LNP exhibits a stable nanostructure, in which LNP plays a key role in effectively protecting and transporting mRNA to cells. Luciferase is a bioluminescent reporter gene for gene regulation and functional studies. Firefly Luciferase mRNA-LNP expresses firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Firefly luciferase mRNA-LNP is studied in research for RNA delivery, cell viability, and translation efficiency .

HY-143702

Fluorescent DOTAP NBD-DOTAP		Cationic Lipids
Fluorescent DOTAP (NBD-DOTAP) is a cationic lipid which can be used for nucleic acid and protein delivery. Fluorescent DOTAP is labeled with a fluorophore NBD (maximum excitation/emission wavelength ∼463/536 nm). Fluorescent DOTAP can be used for gene delivery systems, drug delivery, as well as cell imaging and nanocarrier tracking. Fluorescent DOTAP is an ideal candidate for both biological and pharmaceutical formulation (e.g. co-delivery of vaccines) research .

HY-153845

RNA Aptamer Broccoli sodium		Aptamers
RNA Aptamer Broccoli sodium is a 49-nucleotide nucleic acid aptamer that is much shorter than Spinach and Spinach2. It exhibits bright green fluorescence when binding to DFHBI or DFHBI-1T (a soluble analog of the green fluorescent protein label). RNA Aptamer Broccoli sodium can be used for RNA expression or localization in living cells .

HY-153232

eGFP circRNA-LNP		Liposome
eGFP circRNA-LNP is a lipid nanoparticle (LNP) containing eGFP circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. eGFP circRNA carries Enhanced Green Fluorescent Protein (Enhanced Green Fluorescent Protein) eGFP, which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry .

HY-171493

mCherry mRNA(N1-Me-Pseudo UTP)		mRNA
mCherry mRNA(N1-Me-Pseudo UTP) is a reporter mRNA encoding a red fluorescent protein, suitable for gene expression analysis, cell viability assays, and in vivo imaging. mCherry, derived from mushroom coral, is a widely used red fluorescent protein tracer in biotechnology applications.

HY-153843

RNA Aptamer Corn sodium		Aptamers
RNA Aptamer Corn (sodium) is a 28-nt-long aptamer that is substantially shorter than Spinach and Spinach2 and exhibits bright red fluorescence upon binding DFHO (a soluble analog of the intrinsic fluorophore of red fluorescent protein), RNA Aptamer Corn (sodium) can be used to visualize RNA expression or localization in live cells which have been soaked with chromophores. The Corn-DFHO does not become appreciably cytotoxic when illuminated. And most importantly, Corn-DFHO exhibits markedly increased photostability compared to other aptamer-chromophore complexes both in vitro and in vivo. (36 nt Corn construct: 5'-GGCGCGAGGAAGGAGGUCUGAGGAGGUCACUGCGCC-3'; A 36-nt RNA construct, comprised of the 28-nt minimal Corn sequence extended proximally with a 4 base-pair stem.)

HY-153231A

eGFP mRNA-LNP (500 ng/μL)		Liposome
eGFP mRNA-LNP (500 ng/μL) is a lipid nanoparticle (LNP) containing eGFP mRNA. eGFP mRNA-LNP carries Enhanced Green Fluorescent Protein (eGFP), which will express green fluorescent protein after entering the cell. eGFP is commonly used as a reporter gene detectable by fluorescence microscopy or flow cytometry (excitation wavelength = 488 nm; emission wavelength = 535/40 bandpass). eGFP mRNA-LNP can be used for RNA delivery, translation efficiency and cell viability .

HY-118667

Dehydroergosterol 1 Publications Verification		Cholesterol
Dehydroergosterolis a naturally occurring fluorescent sterol analog (Ex/Em=325/375 nm), which mimics the properties of cholesterol in cell membranes. DehydroergosterolEasily conjugated by cholesterol-binding proteins for real-time imaging in live cells. DehydroergosterolThe sterol environment and intracellular sterol transport in vivo can be probed/elucidated in real time .

HY-174496

eGFP mRNA (5moU)		mRNA Reporter Genes
eGFP mRNA (5moU) expresses a green fluorescent protein, originally isolated from the jellyfish, Aequorea victoria. EGFP is a commonly used direct detection reporter in mammalian cell culture, yielding bright green fluorescence. The substitution with 5’-Methoxyuridine (5moU) improves protein expression and reduces innate immune response.

HY-174795

mCherry mRNA		mRNA Reporter Genes
mCherry mRNA encodes the mCherry fluorescent protein, which is derived from Anaplasma marginale. mCherry can be used as a fluorescent tracer in transfection and transgenic experiments or as a reporter of gene expression.

HY-174789

Gaussia luciferase mRNA		mRNA Reporter Genes
Gaussia luciferase (GLuc) mRNA will express a luciferase protein, derived from the Gaussia princeps. luciferases are widely used in biotechnology, for microscopy and as reporter genes, for many of the same applications as fluorescent proteins.

HY-N15995

DOPE-PEG(2000) Carboxylic acid sodium		Pegylated Lipids
DOPE-PEG(2000) Carboxylic acid sodium is a stabilizer. DOPE-PEG(2000) Carboxylic acid sodium produce a coating around the ferrofluid droplet chains which are dispersed in 5CB. DOPE-PEG(2000) Carboxylic acid sodium tends to fold, effectively shielding the surrounding LC molecules from the homeotropic anchoring at the droplet interface and leading to smaller deformations and thus also creating a more stable interface .

HY-174486

mCherry mRNA (5moU)		mRNA Reporter Genes
mCherry mRNA (5moU) encodes the fluorescent protein, mCherry, which is derived from DsRed, a protein found in Discosoma sp. mCherry is a monomeric fluorophore with a peak absorption at 587 nm and emission at 610 nm. It is stable and resistant to photobleaching.

HY-174794

Cas9-T2A-GFP mRNA		mRNA Gene Editing
The Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and a green fluorescent protein (GFP), which could be used in genome engineering experiments.

HY-174793

Cas9-T2A-GFP mRNA (N1-Methylpseudo-UTP)		mRNA Gene Editing
The Cas9-T2A-GFP mRNA encodes a Cas9 nuclease gene with two nuclear localization signals (NLS) and a green fluorescent protein (GFP), which could be used in genome engineering experiments. The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.

HY-174483

Renilla luciferase mRNA (5moU)		mRNA Reporter Genes
Renilla luciferase (RLuc) mRNA (5moU) will express a luciferase protein, originally isolated from the Renilla muelleri (Sea pansy). Luciferases are widely used in biotechnology, for microscopy and as reporter genes, for many of the same applications as fluorescent proteins.

HY-174792

Cre-T2A-GFP mRNA		mRNA Gene Editing
The Cre-T2A-GFP mRNA is a capped and polyadenylated messenger RNA encoding a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP).

HY-153230

Firefly luciferase circRNA-LNP		Liposome
Firefly luciferase circRNA-LNP is a lipid nanoparticle (LNP) containing Firefly luciferase circRNA, suitable for assays of RNA delivery, translation efficiency, cell viability, etc. Luciferase is commonly used as a bioluminescent reporter gene for gene regulation and function studies. Firefly Luciferase circRNA will express firefly luciferase protein after entering the cells, which is often used for promoter activity detection or dual fluorescent molecular complementation experiments. Common luciferase are firefly luciferase and sea kidney luciferase .

HY-150360

Renilla luciferase mRNA		mRNA Reporter Genes
Renilla luciferase (RLuc) mRNA will express a luciferase protein, originally isolated from the Renilla muelleri (Sea pansy). Luciferases are widely used in biotechnology, for microscopy and as reporter genes, for many of the same applications as fluorescent proteins.

HY-174791

Cre-T2A-GFP mRNA (N1-Methylpseudo-UTP)		mRNA Gene Editing
The Cre-T2A-GFP mRNA is a capped and polyadenylated messenger RNA encoding a Cre recombinase with a nuclear localization sequence (NLS) and a green fluorescent protein (GFP). The incorporation of N1-Methylpseudo-UTP can reduce the immunogenicity of the resulting mRNA.

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