147963-22-2
147963-22-2
Chemical Structure
CellTracker Blue CMAC
- CAS No.: 147963-22-2
- Formula:C10H8ClNO2
- Molecular Weight:209.63
InChIKey: VIEYMVWPECAOCY-UHFFFAOYSA-N
SMILES: O=C1OC2=C(C(CCl)=C1)C=CC(N)=C2
Biological Activity: CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels[1][2][3].
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CellTracker Blue CMAC | 98.84% | CellTracker Blue CMAC is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels. | ||||||||||||||||||||
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CellTracker Blue CMAC (solution) | CellTracker Blue CMAC (solution) is a non-fluorescent cell membrane permeable dye. The chloromethyl groups of CellTracker Blue CMAC are enzymatically cleaved by intracellular glutathione (GSH) to generate a fluorescent product (blue fluorescence, Ex/Em: 360/460 nm). CellTracker Blue CMAC is suitable for long-term cell tracking (up to 72 hours) and cell proliferation studies, and can also quantify GSH levels. Solvent and concentration: DMSO: 10 mM |
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References
- [1]. Horobin R W, et al. Reactive dyes for living cells: Applications, artefacts, and some comparisons with textile dyeing. Coloration technology, 2022,138(1):3-15.
- [2]. King N, et al. A new method of quantifying glutathione levels in freshly isolated single superfused rat cardiomyocytes. J Pharmacol Toxicol Methods. 2004 Nov-Dec;50(3):215-22. [Content Brief]
- [3]. Dludla PV, et al. A dose-dependent effect of dimethyl sulfoxide on lipid content, cell viability and oxidative stress in 3T3-L1 adipocytes. Toxicol Rep. 2018 Oct 4;5:1014-1020. [Content Brief]
