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  4. 4-Methylumbelliferone sodium salt

4-Methylumbelliferone sodium salt  (Synonyms: Hymecromone sodium salt; 4-MU sodium salt)

Cat. No.: HY-N0187A Purity: 99.88%
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4-Methylumbelliferone (sodium salt) is a coumarin derivative. 4-Methylumbelliferone (sodium salt) can be used as a standard to quantify the free 4-methylumbelliferone released as a result of enzyme-substrate action. 4-Methylumbelliferone (sodium salt) inhibits hyaluronan production in vitro. 4-Methylumbelliferone (sodium salt) can be studied in ovarian cancer research.

For research use only. We do not sell to patients.

CAS No. : 5980-33-6

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
10 mM * 1 mL in DMSO In-stock
Solid
1 g In-stock
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Based on 7 publication(s) in Google Scholar

Other Forms of 4-Methylumbelliferone sodium salt:

4-Methylumbelliferone sodium salt Related Antibodies

Top Publications Citing Use of Products

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: J Transl Med. 2025 Feb 24;23(1):224.  [Abstract]

    Representative western blots and statistical analysis of CD68, OPN, ARG1, CD206, collagen I, and αSMA protein expression levels in ITIH5 overexpression and control co-culture systems treated with different concentrations of 4-Methylumbelliferone (0-1 mM, 24 h).

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Aug 7;26(15):7637.  [Abstract]

    Electrophoresis analysis and staining of HA extracted from conditioned medium by the same cells, in the presence or absence of 4-Methylumbelliferone (4MU) and HYAL (6 U/mL). The analyzed samples include: (1) INS1E/SVF control, (2) INS1E/SVF treated with 4-Methylumbelliferone (4MU), (3) INS1E/SVF treated with HYAL (6 U/mL).

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Aug 7;26(15):7637.  [Abstract]

    Phase contrast Images of INS1E pseudo-islets treated or untreated with 4-Methylumbelliferone (4MU) for 24 h.

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Aug 7;26(15):7637.  [Abstract]

    Immunofluorescence analysis of INS1E cells cultured in 2D conditions, with or without 4-Methylumbelliferone (4MU) treatment, stained with anti-insulin antibody, DAPI, and Phalloidin.

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Aug 7;26(15):7637.  [Abstract]

    Phase contrast images of INS1E cells grown in 2D conditions, with or without 0.250 mM 4-Methylumbelliferone (4MU) cultivated on a tissue culture plate.

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Aug 7;26(15):7637.  [Abstract]

    Quantification of basal insulin secretion in INS1E cells grown in 2D and 3D conditions, with or without 0.250 mM of 4-Methylumbelliferone (4MU). Insulin levels were normalized to the total protein content (mg) of cell extracts.

    4-Methylumbelliferone sodium salt purchased from MedChemExpress. Usage Cited in: Int J Mol Sci. 2025 Aug 7;26(15):7637.  [Abstract]

    Cell viability assessment (MTS assay) of INS1E cells treated with different concentrations of 4-Methylumbelliferone (4MU) (0.5–0.075 mM) for 48 h.

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    • Purity & Documentation

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    Description

    4-Methylumbelliferone (sodium salt) is a coumarin derivative. 4-Methylumbelliferone (sodium salt) can be used as a standard to quantify the free 4-methylumbelliferone released as a result of enzyme-substrate action. 4-Methylumbelliferone (sodium salt) inhibits hyaluronan production in vitro. 4-Methylumbelliferone (sodium salt) can be studied in ovarian cancer research[1][2][3].

    Clinical Trial
    Molecular Weight

    198.15

    Formula

    C10H7NaO3
    CAS No.
    Appearance

    Solid

    Color

    Off-white to light yellow

    SMILES

    O=C1C=C(C2=CC=C(C=C2O1)O[Na])C
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    Store at room temperature, keep dry and cool

    In solvent -80°C 1 year
    -20°C 6 months
    Solvent & Solubility
    In Vitro: 

    DMSO : 50 mg/mL (252.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 5.0467 mL 25.2334 mL 50.4668 mL
    5 mM 1.0093 mL 5.0467 mL 10.0934 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    • Molarity Calculator

    • Dilution Calculator

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    Volume (start)

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

    Dosage

    mg/kg

    Animal weight
    (per animal)

    g

    Dosing volume
    (per animal)

    μL

    Number of animals

    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    Purity & Documentation
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO 1 mM 5.0467 mL 25.2334 mL 50.4668 mL 126.1670 mL
    5 mM 1.0093 mL 5.0467 mL 10.0934 mL 25.2334 mL
    10 mM 0.5047 mL 2.5233 mL 5.0467 mL 12.6167 mL
    15 mM 0.3364 mL 1.6822 mL 3.3645 mL 8.4111 mL
    20 mM 0.2523 mL 1.2617 mL 2.5233 mL 6.3084 mL
    25 mM 0.2019 mL 1.0093 mL 2.0187 mL 5.0467 mL
    30 mM 0.1682 mL 0.8411 mL 1.6822 mL 4.2056 mL
    40 mM 0.1262 mL 0.6308 mL 1.2617 mL 3.1542 mL
    50 mM 0.1009 mL 0.5047 mL 1.0093 mL 2.5233 mL
    60 mM 0.0841 mL 0.4206 mL 0.8411 mL 2.1028 mL
    80 mM 0.0631 mL 0.3154 mL 0.6308 mL 1.5771 mL
    100 mM 0.0505 mL 0.2523 mL 0.5047 mL 1.2617 mL
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    4-Methylumbelliferone sodium salt Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    4-Methylumbelliferone5980-33-6Hymecromone4-MUBiochemical Assay ReagentsInhibitorinhibitorinhibit

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