Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
formalin-induced pain model
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "formalin-induced pain model" in MCE Product Catalog:
Cat. No.: HY-N1884
CAS No.: 29424-96-2
Synonyms: (-)-Naringenin 4',7-dimethyl Ether; (-)-NRG-DM
Category:
Flavonoids Monophenols Flavonones Other Diseases Phenols Alpinia officinarum Hance Plants Disease Research Fields Zingiberaceae
Target:
Cat. No.: HY-176063
CAS No.: 3084843-71-7
Target:
Research Areas:
TRPV1 antagonist 11 (compound 2ac) is a potent TRPV1 antagonist with an IC50 of 29.3 nM. TRPV1 antagonist 11 is a potent μ-opioid receptor (MOR) agonist with a Ki of 60.3 nM. TRPV1 antagonist 11, a pyrimidine piperazine, exhibits pain relieving effects by antagonizing TRPV1 and stimulating MOR. TRPV1 antagonist 11 shows a potent, dose-dependent anti-nociceptive effect in a Formalin-induced pain model in mice .
Cat. No.: HY-N19281
CAS No.: 57419-60-0
Target:
Cat. No.: HY-182351
CAS No.: 253306-39-7
Target:
Research Areas:
ONO-2921 is an orally active and selective N-type calcium channel blocker. ONO-2921 functionally blocks N-type calcium channels. ONO-2921 reduces paw withdrawal responses during persistent nociception and hyperalgesia to heat in neuropathic pain models. ONO-2921 can be used for research on neuropathic pain and nociceptive pain .
Cat. No.: HY-183144
CAS No.: 141575-50-0
Target:
Research Areas:
Vedaclidine is an orally active muscarinic acetylcholine receptor (mAChR) modulator with mixed receptor activity, which activates muscarinic M2 and M4 receptors and blocks muscarinic M1, M3 and M5 receptors. Vedaclidine exerts its activity through interaction with spinal M4 muscarinic receptors, and does not induce hypothermia or excessive salivation. Vedaclidine can be used in research related to pain, neuropathic pain and inflammatory pain states .
Cat. No.: HY-184331
Target:
Research Areas:
FAAH-IN-10 is a FAAH inhibitor and TRPV1 antagonist, with an IC50 of 0.57 μM against human FAAH. FAAH-IN-10 regulates FAAH activity, antagonizes TRPV1 activity, and exhibits analgesic and anti-inflammatory activities. FAAH-IN-10 does not induce TRPV1-mediated hyperthermia. FAAH-IN-10 can be used for pain-related research .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
