3 Results for "

hepatic metastasis

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "hepatic metastasis" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-N2830
CAS No.: 21499-24-1
Agrimonolide is a phenethyl isocoumarin compound discovered from Agrimonia pilosa, exhibiting anti-inflammatory, antioxidant, and anticancer activities. Agrimonolide inhibits NF-κB, MAPK, and TLR4-mediated neuroinflammatory signaling, suppresses Notch and JAK2/STAT3 signaling to modulate Th17/Treg balance and maintain the intestinal barrier. Agrimonolide decreases HIF1A expression, inhibits glycolysis, and induces ferroptosis and cell cycle arrest via the mTOR pathway in tumor models, thereby suppressing cancer cell viability, proliferation, and metastasis. Agrimonolide exerts hepatoprotective and anti-fibrotic effects by regulating bile acid transporter expression and reducing hepatic bile acid accumulation. Agrimonolide is used for research on ulcerative colitis, ovarian cancer, non-small cell lung cancer, cholestatic liver injury, and neuroinflammation .
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1
1 Cited Publications
Cat. No.: HY-122591
CAS No.: 1287761-01-6
Purity:  98.69%
Target:  

COX

Research Areas:  

Metabolic Disease Cancer

PTUPB is a potent and dual sEH and COX-2 enzymes inhibitor with IC50 of 0.9 nM and 1.26 μM, respectively .
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Cat. No.: HY-186158
CAS No.: 1002722-97-5
Target:  

Drug Intermediate

Research Areas:  

Cancer

HOOC-OXA-COOH is an anionic prodrug of Oxaliplatin (HY-17371). HOOC-OXA-COOH can be loaded onto nanomotors via electrostatic interaction, and undergoes cascade activation by H2S and endogenous glutathione in the tumor microenvironment to release cytotoxic Pt 2+. HOOC-OXA-COOH can be used in the research of colon cancer .
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