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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
human Notum carboxylesterase
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "human Notum carboxylesterase" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-P79357
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Notum; HNotum; Notum, Palmitoleoyl-Protein carboxylesterase; Notum Pectinacetylesterase Homolog (Drosophila); [Wnt Protein] O-Palmitoleoyl-L-Serine Hydrolase; Notum Pectinacetylesterase Homolog; Palmitoleoyl-Protein carboxylesterase Notum; Protein Notum H
Species:
Human
Source:
CHO
Cat. No.: HY-182632
CAS No.: 1875037-24-3
Target:
Research Areas:
LP-935001 is a Notum carboxylesterase inhibitor with an IC50 of 0.4 nM.LP-935001 prevents palmitoleate group removal from Wnt proteins, restores Wnt/β-catenin signaling.LP-935001 enhances cortical bone thickness in rodent models.LP-935001 can be used for the research of bone loss/nonvertebral fractures .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
