![Poly[(R)-3-hydroxybutyrate]](https://file.medchemexpress.com/product_pic/hy-184779.gif "Click to View Poly[(R)-3-hydroxybutyrate] Product Detail")
Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
human fibrosarcoma
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "human fibrosarcoma" in MCE Product Catalog:
20
20 Publications Verification
Cat. No.: HY-B0581
CAS No.: 24584-09-6
Synonyms: ICRF-187; ADR-529; NSC-169780
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .
13
13 Cited Publications
Cat. No.: HY-W013523
CAS No.: 65182-56-1
2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells .
2
2 Cited Publications
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P11143A
Target:
Research Areas:
Cat. No.: HY-W047478
CAS No.: 4630-20-0
Synonyms: NSC 10154
Target:
Cat. No.: HY-174929A
Synonyms: DBCO-PEG5000-NH2
Target:
ANB-NOS is a heterobifunctional crosslinker with lipophilic, uncharged properties suitable for intracellular conjugation. ANB-NOS contains an amine-reactive Nhydroxysuccinimide (NHS) ester and a photoactivatable nitrophenyl azide. ANB-NOS can be used for the research of fibrosarcoma and mammary adenocarcinoma .
Cat. No.: HY-N10158
CAS No.: 207792-17-4
Target:
Research Areas:
1,7-Bis(4-hydroxyphenyl)-3-hydroxy-1,3-heptadien-5-one (compound 39), a diarylheptanoid, exhibits antiproliferative activity towards human HT-1080 fibrosarcoma and murine colon 26-L5 carcinoma cells .
Cat. No.: HY-N3215
CAS No.: 24338-53-2
Target:
Cat. No.: HY-B0581R
CAS No.: 24584-09-6
Synonyms: ICRF-187 (Standard); ADR-529 (Standard); NSC-169780 (Standard)
Target:
Research Areas:
Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
Dexrazoxane (Standard) is the analytical standard of Dexrazoxane. This product is intended for research and analytical applications. Dexrazoxane, as an intracellular iron chelating agent, reduces the formation of superoxide radicals and has cardioprotective, anti-inflammatory, antioxidant, anti-tumor and neuroprotective activities. Dexrazoxane inhibits ferroptosis of H9c2 cells by inhibiting HMGB1. Dexrazoxane induces DNA damage and apoptosis in human fibrosarcoma cells .
Cat. No.: HY-173399
Target:
Research Areas:
hSTING activator-1 (Compound 68) is a STING agonist. hSTING activator-1 can effectively activate multiple human STING variants (R232, H232, HAQ) with EC50 values of 56 nM, 89 nM and 51 nM, respectively. hSTING activator-1 activates the type I interferon pathway by directly binding to STING protein and stabilizing its conformation, promoting downstream IRF3 phosphorylation and cytokine release. hSTING activator-1 inhibits fibrosarcoma tumor growth and has potential in cancer research .
Cat. No.: HY-P11143
CAS No.: 1900734-29-3
Target:
Research Areas:
Cat. No.: HY-182419
CAS No.: 904680-01-9
A-849519 is a reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 19 nM. A-849519 binds to the active site of the Mn 2+ form of human MetAP-2, where the oxygen atom of one acidic functional group interacts with the manganese ion, and another heteroatom binds to the water molecule above the two manganese ions, thereby functionally inhibiting enzyme activity. A-849519 inhibits the methionine processing activity of MetAP-2 as well as the proliferation of fibrosarcoma cells. A-849519 can be used in studies related to fibrosarcoma .
Cat. No.: HY-W047478R
CAS No.: 4630-20-0
Synonyms: NSC 10154 (Standard)
Category:
Target:
Research Areas:
1-(3-Carboxypropyl)-3,7-dimethylxanthine is the major circulating oxidative carboxylation metabolite of Pentoxifylline (HY-B0715). 1-(3-Carboxypropyl)-3,7-dimethylxanthine protects fibrosarcoma cells against the cytotoxic effect of TNF-α .
Cat. No.: HY-182377
CAS No.: 123598-19-6
Target:
Research Areas:
DT-5461 is an IL-1 and TNF-α antagonist. DT-5461 competitively binds lipid A-binding sites on macrophage receptors, blocks LPS (HY-D1056)-initiated signaling, inhibits LPS-induced cytokine release, prevents LPS-induced serum cytokine production in mice, and protects against LPS-induced lethal endotoxemia. DT-5461 can be used for the research of lethal endotoxemia, medullary tubular mammary carcinoma, poorly differentiated colon adenocarcinoma, squamous-cell lung carcinoma, and gelatinous gastric adenocarcinoma .
Cat. No.: HY-N19737
CAS No.: 62560-99-0
Target:
Cat. No.: HY-184779
CAS No.: 29435-48-1
Synonyms: PHB
Target:
Research Areas:
Poly[(R)-3-hydroxybutyrate] (PHB) is a polyhydroxyalkanoate polymer with biocompatibility and processability. Poly[(R)-3-hydroxybutyrate] can be used to prepare drug delivery nanoparticles and tissue engineering scaffolds. Poly[(R)-3-hydroxybutyrate] is applicable to research related to drug delivery, tissue engineering and wound dressing materials .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
