DBCO-PEG5000-Amine
DBCO-PEG5000-Amine (DBCO-PEG5000-NH2) is a polyethylene glycol derivative containing dibenzocyclooctyne. DBCO-PEG-Amine is a universal, modular "bridge molecule": it forms stable covalent linkage with target materials (e.g., MSN or polymers) via the amino group at one end, while the DBCO group at the other end enables efficient, specific, and biocompatible click chemical conjugation with any azide-bearing biological entities (e.g., bacteria, cells) in subsequent steps.
For research use only. We do not sell to patients.
- Molecular Weight:5000 (Average)
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
DBCO-PEG-NH2 can be used to synthesize polymer backbones for constructing hyaluronidase nanogels[1].
DBCO-PEG-NH2 can be used to modify mesoporous silica nanoparticles for constructing a "bacteria-nanoparticle" hybrid carrier (Bac-MSN)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 5000 (Average)
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SMILES
NCCOCCNC(CCC(N1CC2=C(C=CC=C2)C#CC3=C1C=CC=C3)=O)=O.[n]
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Synonyms
DBCO-PEG5000-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- DBCO-PEG5000-Amine
- DBCO-PEG5000-NH2
- Biochemical Assay Reagents
- triazole bonds
- copper-free click chemistry
- azide-containing molecules
- mesoporous silica nanoparticles
- solid tumors
- 3D collagen gels
- HT1080 human fibrosarcoma cell
- Escherichia coli
- human fibrosarcoma
- strain-promoted azide-alkyne cycloaddition
- Inhibitor
- inhibitor
- inhibit