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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
human melanocortin 1 receptor
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "human melanocortin 1 receptor" in MCE Product Catalog:
Synonyms: MT-7117
Target:
Research Areas:
Dersimelagon (MT-7117) is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon can be used for the research of skin pigmentation .
Cat. No.: HY-P1545A
Synonyms: α1-17-ACTH TFA
Target:
Research Areas:
Cat. No.: HY-109114A
CAS No.: 2490660-87-0
Synonyms: MT-7117 phosphate
Target:
Research Areas:
Dersimelagon phosphate is an orally active, selective melanocortin 1 receptor (MC1R) agonist with EC50 values of 8.16, 3.91, 1.14 and 0.251 nM for human (h), cynomolgus monkey (cm), mouse (m) and rat (r) MC1R, respectively. Dersimelagon phosphate shows good affinity for hMC1R and hMC4R with Ki values of 2.26, 32.9 nM, respectively. Dersimelagon phosphate can be used for the research of skin pigmentation .
Target:
Research Areas:
Cat. No.: HY-P12217
Target:
Research Areas:
Cyclic MC4R peptide agonist-1 is a cyclic peptide agonist of the melanocortin-4 receptor (melanocortin-4 receptor). Cyclic MC4R peptide agonist-1 activates the human melanocortin-4 receptor via an alternative activation motif centered on APWR, and this activation process is independent of the classical HFRW pharmacophore. Cyclic MC4R peptide agonist-1 inhibits signal transduction of the human melanocortin-3 receptor and melanocortin-5 receptor. Cyclic MC4R peptide agonist-1 is used in research related to obesity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
