1 Result for "

hypothalamus-pituitary-ovary axis

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "hypothalamus-pituitary-ovary axis" in MCE Product Catalog:

Cat. No.: HY-B1012
CAS No.: 152-43-2
Synonyms: W-3566
Quinestrol (W-3566) is an orally effective synthetic estrogen compound that acts on CYP3A4, CYP1A2, and GnRH. Quinestrol interferes with GnRH release and disrupts the hypothalamic-pituitary-ovarian axis. Quinestrol downregulates the gene expression of follicle-stimulating hormone β and luteinizing hormone β, induces oxidative stress, damages reproductive organs, reduces sperm density and motility, increases sperm malformation rate, and alters the levels of sex hormones such as testosterone, luteinizing hormone, estradiol, and progesterone. Quinestrol can be used in studies related to reproductive function regulation .
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