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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
61 Results for "
immunoglobulin G1
" in MedChemExpress (MCE) Product Catalog:
Products (61)
61 Results for "immunoglobulin G1" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: LNP023
Target:
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Iptacopan (LNP023) is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G) .
13
13 Publications Verification
Synonyms: LNP023 hydrochloride
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Research Areas:
Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan hydrochloride exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan hydrochloride can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G) .
2
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1
1 Cited Publications
Cat. No.: HY-P99033
CAS No.: 1905409-39-3
Synonyms: BTCT-4465A; RG-7828; RO7030816
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P9920A
CAS No.: 947687-13-0
1
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1
1 Cited Publications
Cat. No.: HY-P73143
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P70796
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IGHG1; Ig Gamma-1 Chain C Region NIE; immunoglobulin Heavy Constant Gamma 1 (G1m Marker); Ig Gamma-1 Chain C Region KOL; Constant Region Of Heavy Chain Of IgG1; Ig Gamma-1 Chain C Region EU; immunoglobulin Heavy Constant Gamma 1; Ig Gamma-1 Chain C Region
Species:
Human
Source:
HEK293
Cat. No.: HY-P99955
CAS No.: 2431972-52-8
Synonyms: AMG 451; KHK4083
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Cat. No.: HY-P99367
CAS No.: 2484870-90-6
Synonyms: DS-7300a Antibody; MABX-9001A Antibody
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Cat. No.: HY-P99521
CAS No.: 2138442-13-2
Synonyms: XmAb14045
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Cat. No.: HY-P990047
CAS No.: 2761478-99-1
Synonyms: AMG133 antibody
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Cat. No.: HY-P99036
CAS No.: 1296818-77-3
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Cat. No.: HY-P990045
CAS No.: 2749515-10-2
Synonyms: ALE.F02
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Cat. No.: HY-P99382
CAS No.: 2039148-04-2
Synonyms: JTX 2011; 37A10
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Cat. No.: HY-P99157
CAS No.: 1895083-75-6
Synonyms: Mab 8H9
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Omburtamab (Mab 8H9) is a mouse monoclonal immunoglobulin G1 (IgG1) antibody targeting B7-H3. Omburtamab specifically binds to the glycoprotein antigen B7-H3, which is widely expressed on the surface of tumor cells. As a targeting carrier for recombinant toxins, it delivers PE38 to inhibit cellular protein synthesis and induce cytotoxicity in antigen-expressing cancer cells. Omburtamab can be used in research related to glioma, breast cancer, osteosarcoma and neuroblastoma .
Cat. No.: HY-P990032
CAS No.: 2574438-65-4
Synonyms: EOS-448; EOS884448; GSK4428859A
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Cat. No.: HY-P990021
CAS No.: 2635404-72-5
Synonyms: TRL1068
Cat. No.: HY-P99551
CAS No.: 1374419-41-6
Synonyms: KBSA301; AR-301
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Cat. No.: HY-P991661
CAS No.: 1607838-85-6
Research Areas:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
