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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
9 Results for "
intrinsic coagulation pathway
" in MedChemExpress (MCE) Product Catalog:
Products (9)
9 Results for "intrinsic coagulation pathway" in MCE Product Catalog:
Cat. No.: HY-E70544B
CAS No.: 9001-29-0
Research Areas:
Canine Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Canine Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Canine Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Canine Factor X can be used in studies related to Factor X deficiency .
Cat. No.: HY-172400
CAS No.: 3046390-69-3
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FXIa-IN-16 is an orally active selective FXIa inhibitor with an IC50 of 0.19 nM. FXIa-IN-16 exerts highly selective competitive inhibition on endogenous FXIa, blocks the thrombin amplification loop to inhibit thrombosis, while preserving exogenous physiological hemostatic function. FXIa-IN-16 can be used in thrombosis-related research .
Cat. No.: HY-162646
CAS No.: 3047411-80-0
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FXIIa-IN-5 (Compound 4J) is an orally active, selective inhibitor for factor XIIa (FXIIa), with IC50 of 21 nM. FXIIa-IN-5 inhibits the intrinsic coagulation pathways, and exhibits anti-inflammatory and antithrombotic activity in Carrageenan (HY-125474)-induced mice thrombosis models. FXIIa-IN-5 exhibits moderate pharmacokinetic characteristics and slightly toxicity (at 100 mg/kg) .
Cat. No.: HY-E70393J
Bovine Factor XIa is an enzyme, which is involved in the intrinsic pathway of blood coagulation. Bovine Factor XIa is highly selective and exhibits a minimal extended substrate recognition site of at least five residues long. Bovine Factor XIa is reactive as Bovine Factor IXa (HY-E70393I) does, that it cleaves all the peptides bearing factor IX activation site sequences .
Cat. No.: HY-E70544A
CAS No.: 9001-29-0
Research Areas:
Bovine Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Bovine Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Bovine Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Bovine Factor X can be used in studies related to Factor X deficiency .
Cat. No.: HY-P991994
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Research Areas:
Cat. No.: HY-E70393K
Target:
Research Areas:
Mouse Factor XII (Recombinant) is a mouse-derived recombinant coagulation protein. Factor XII is a multi-domain protein that contains two fibronectin-binding consensus sequences, two epidermal growth factor domains, one Kringle domain, one proline-rich domain, and one catalytic domain. Factor XII plays a role in thrombosis. Mouse Factor XII (Recombinant) can be used in studies related to arterial thrombosis .
Cat. No.: HY-E70393L
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Cyno Factor Xll (Recombinant) is a Cynomolgus macaque-derived recombinant coagulation protein. Factor XII is a multi-domain protein that contains two fibronectin-binding consensus sequences, two epidermal growth factor domains, one Kringle domain, one proline-rich domain, and one catalytic domain. Factor XII plays a role in thrombosis. Cyno Factor Xll (Recombinant) can be used in studies related to arterial thrombosis .
Cat. No.: HY-E70544C
CAS No.: 9001-29-0
Research Areas:
Rabbit Factor X is a vitamin K-dependent plasma serine protease that is activated to generate Factor Xa. Rabbit Factor X mediates the common coagulation pathway and catalyzes the conversion of prothrombin to thrombin . Rabbit Factor X is the first enzyme to act in the common pathway of thrombosis in the coagulation cascade. Rabbit Factor X can be used in studies related to Factor X deficiency .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
