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FXIIa-IN-5

FXIIa-IN-5 (Compound 4J) is an orally active, selective inhibitor for factor XIIa (FXIIa), with IC50 of 21 nM. FXIIa-IN-5 inhibits the intrinsic coagulation pathways, and exhibits anti-inflammatory and antithrombotic activity in Carrageenan (HY-125474)-induced mice thrombosis models. FXIIa-IN-5 exhibits moderate pharmacokinetic characteristics and slightly toxicity (at 100 mg/kg).

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  • CAS No.: 3047411-80-0
  • 화학식: C26H29N7O
  • 분자량:455.55
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FXIIa-IN-5 Chemical Structure
    FXIIa-IN-5 Chemical Structure
CAS No.: 3047411-80-0
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  • FXIIa-IN-5 Chemical Structure
    FXIIa-IN-5 Chemical Structure
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  • FXIIa-IN-5