3 Results for "

mitochondrial fuel oxidation

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "mitochondrial fuel oxidation" in MCE Product Catalog:

1
Dodecanoylcarnitine
Dodecanoylcarnitine
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1 Cited Publications
Cat. No.: HY-113166
CAS No.: 25518-54-1
Purity:  99.75%
Synonyms: (-)-Lauroylcarnitine
Category:  

Immune System Disorder Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields

Target:  

Endogenous Metabolite

Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
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Oltipraz metabolite M2
Oltipraz metabolite M2
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Cat. No.: HY-134998
CAS No.: 84201-40-1
Target:  

HIF/HIF Prolyl-Hydroxylase Mitochondrial Metabolism Drug Metabolite p38 MAPK

Research Areas:  

Metabolic Disease Inflammation/Immunology

Oltipraz metabolite M2, an active metabolite of Oltipraz (HY-12519), is an orally active HIF-1α inhibitor. Oltipraz metabolite M2 increases mitochondrial fuel oxidation and inhibits lipogenesis in the liver by dually activating AMPK in high-fat diet (HFD)-fed mice. Oltipraz metabolite M2 can be used for hepatic steatosis and steatohepatitis research .
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Dodecanoylcarnitine (Standard)
Dodecanoylcarnitine (Standard)
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Cat. No.: HY-113166R
CAS No.: 25518-54-1
Synonyms: (-)-Lauroylcarnitine (Standard)
Category:  

Microorganisms Immune System Disorder Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite

Target:  

Reference Standards Endogenous Metabolite

Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine (HY-113166). This product is intended for research and analytical applications. Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .
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