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mosaic

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48

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3

Fluorescent Dyes

4

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20

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2

Isotope-Labeled Compounds

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-D0815
    Propidium Iodide
    135+ Cited Publications

    		 Fluorescent Dye DNA/RNA Synthesis Others
    Propidium Iodide (PI) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis), and is often used in flow cytometry analysis.
    Propidium Iodide
  • HY-Y0507
    DL-Serine
    1 Publications Verification

    		 TMV Infection Cancer
    DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .
    DL-Serine
  • HY-DY1006
    Propidium Iodide (solution)

    		Fluorescent Dye DNA/RNA Synthesis Others
    Propidium Iodide (PI) (solution) is a nuclear staining agent that stains DNA. Propidium Iodide is an analogue of ethidine bromide that emits red fluorescence upon embedding in double-stranded DNA. Propidium Iodide cannot pass through living cell membranes, but it can pass through damaged cell membranes to stain the nucleus. Propidium Iodide has a fluorescence wavelength of 493/617 nm and a wavelength of 536/635 nm after Mosaic with DNA. Propidium Iodide is commonly used in the detection of apoptosis (apoptosis) or necrosis (necrosis) , and is often used in flow cytometry analysis.
    Solvent and Concentration: Sterile water: 1 mg/mL
    The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.
    Propidium Iodide (solution)
  • HY-B0821
    Pymetrozine
    1 Publications Verification

    CGA 215944

    		 Environmental Pollutants Bacterial Infection
    Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae (Sulzer).
    Pymetrozine
  • HY-41404
    Piperonylic acid

    2H-1,3-benzodioxole-5-carboxylic acid

    		 Cytochrome P450 Interleukin Related EGFR IGF-1R Infection Others Cancer
    Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities .
    Piperonylic acid
  • HY-Y0507S
    DL-Serine-2,3,3-d3

    		TMV Isotope-Labeled Compounds Infection Cancer
    DL-Serine-2,3,3-d3 is the deuterium labeled DL-Serine. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV) .
    DL-Serine-2,3,3-d3
  • HY-P2717
    Ac-YVAD-AMC

    		Caspase Infection
    Ac-YVAD-AMC is an inhibitor for caspase. Ac-YVAD-AMC inhibits bacteria-induced cell death of hypersensitive response (HR) cells .
    Ac-YVAD-AMC
  • HY-W001084
    Methyl 4-hydroxyphenylacetate

    		Others Infection Cancer
    Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate
  • HY-N4210
    Yadanziolide A

    		TMV Infection Cancer
    Yadanziolide A, isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects .
    Yadanziolide A
  • HY-W017463
    trans-3-(3-Pyridyl)acrylic acid

    		Drug Intermediate TMV Isocitrate Dehydrogenase (IDH) Infection
    trans-3-(3-Pyridyl) acrylic acid is an unsaturated carboxylic acid and synthetic building block, which serves as a synthetic precursor of 3-(3-pyridyl) propanoic acid. trans-3-(3-Pyridyl) acrylic acid can be used to prepare dual mutant IDH1/NAMPT inhibitors and PGE2 antagonist analogs. In addition, trans-3-(3-Pyridyl) acrylic acid exhibits antiviral activity against tobacco mosaic virus (TMV) .
    trans-3-(3-Pyridyl)acrylic acid
  • HY-N13047
    Ningnanmycin

    		TMV SOD Infection
    Ningnanmycin is a plant antiviral agent. Ningnanmycin binds to specific residues on the TMV CP disc, inhibits CP assembly, disassembles the CP disc into monomers, and disrupts the structure of the TMV CP disc to reduce pathogenicity. Ningnanmycin binds to key amino acids of PVY CP, interferes with CP-CP interactions, inhibits CP assembly and virion formation, and blocks PVY replication. Ningnanmycin induces the expression of antiviral response genes PRXIIB, PRXIIE, PUB4 and PER42, thereby activating the host defense system. Ningnanmycin can be used in studies related to Tobacco Mosaic Virus infection and Potato Virus Y infection .
    Ningnanmycin
  • HY-B0821R
    Pymetrozine (Standard)

    CGA 215944 (Standard)

    		 Reference Standards Bacterial Infection
    Pymetrozine (Standard) is the analytical standard of Pymetrozine. This product is intended for research and analytical applications. Pymetrozine is a feeding inhibitor of Homoptera, in preventing transmission of cauliflower mosaic caulimovirus by the aphid species Myzus persicae (Sulzer).
    Pymetrozine (Standard)
  • HY-121255
    (-)-Cryptopleurine

    (R)-Cryptopleurine; NSC 19912

    		 TMV Cancer
    (–)-Cryptopleurine is an alkaloid that has been found in Lauraceae and has diverse biological activities. It inhibits the growth of human A375 melanoma, A431 epidermoid carcinoma, A549 lung, MES-SA uterine sarcoma, and MCF-7 breast cancer cells (IC50=3 nM for all).2 (–)-Cryptopleurine inhibits hypoxia-induced gene expression in a hypoxia response element (HRE) reporter assay (IC50=8.7 nM).3 (–)-Cryptopleurine (500 μg/mL) prevents lesion formation in tobacco (N. tabacum) plants infected with tobacco mosaic virus (TMV). It also inhibits protein synthesis by yeast and mammalian ribosomes.
    (-)-Cryptopleurine
  • HY-117085
    Lobaric acid

    		Phosphatase TMV Lipoxygenase Cancer
    Lobaric acid is a depsipeptide metabolite isolated from Stereocaulon lichen with antioxidant, antiproliferative, antiviral and enzyme inhibitory activities. Lobaric acid scavenges superoxide free radicals (IC50=97.9 μM) and inhibits cancer cell proliferation (EC50 of 15.2-63.9 μg/mL against leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic and lung cancer cell lines). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50=0.87 μM for human recombinant enzyme) and 12(S)-HETE produced by 12(S)-lipoxygenase (IC50=28.5 μM). Lobaric acid (250 μM) also reduced pathological changes in tobacco leaves infected with tobacco mosaic virus (TMV).
    Lobaric acid
  • HY-119458
    Luotonin A

    		Topoisomerase TMV Fungal Infection
    Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity .
    Luotonin A
  • HY-W001084R
    Methyl 4-hydroxyphenylacetate (Standard)

    		Reference Standards Others
    Methyl 4-hydroxyphenylacetate (Standard) is the analytical standard of Methyl 4-hydroxyphenylacetate (HY-W001084). This product is intended for research and analytical applications. Methyl 4-hydroxyphenylacetate is a compound found in the marine fungus Penicillium oxalicum 0312F1. Methyl 4-hydroxyphenylacetate can be Methyl 4-hydroxyphenylacetate inhibits replication of tobacco mosaic virus (TMV) in Nicotiana tabacum leaf discs. Methyl 4-hydroxyphenylacetate shows inhibitory activity against proliferation of cancer cells. Methyl 4-hydroxyphenylacetate can be used for the researches of TMV infection and cancer .
    Methyl 4-hydroxyphenylacetate (Standard)
  • HY-17517
    Tiadinil

    		Fungal Biochemical Assay Reagents Infection
    Tiadinil is a systemic acquired resistance (SAR) inducer, plant elicitor and antifungal agent. Tiadinil promotes the production of herbivore-induced plant volatiles in Camellia sinensis (tea plant). Tiadinil inhibits mycelial growth, spore germination and germ tube elongation of Stagonosporopsis citrulli in vitro. Tiadinil can be used in studies related to vine blight .
    Tiadinil
  • HY-N7532
    Yadanzioside I

    		TMV Infection
    Yadanzioside I is a potent anti-tobacco mosaic virus (TMV) quassinoid with an IC50 of 4.22 μM .
    Yadanzioside I
  • HY-N8024
    Rubinaphthin A

    		TMV Infection
    Rubinaphthin A is a naphthohydroquinone that can be found in the roots of Rubia yunnanensis. Rubinaphthin A exhibits inhibitory activity against tobacco mosaic virus (TMV) .
    Rubinaphthin A
  • HY-N12249
    7-Deoxy-trans-dihydronarciclasine

    		Amyloid-β TMV Infection Neurological Disease Inflammation/Immunology
    7-Deoxy-trans-dihydronarciclasine, an alkaloid, is a tobacco mosaic virus (TMV) inhibitor (IC50: 1.80 μM). 7-Deoxy-trans-dihydronarciclasine is an anti-neuroinflammatory agent. 7-Deoxy-trans-dihydronarciclasine decreases the Aβ and APP levels in the cerebral cortex of Tg2576 mice .
    7-Deoxy-trans-dihydronarciclasine
  • HY-148568
    TMV-IN-2

    		TMV Bacterial Infection Inflammation/Immunology Cancer
    TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor .
    TMV-IN-2
  • HY-P5642
    Retrocyclin-101

    RC-101

    		 Bacterial Ser/Thr Protease Influenza Virus HSV SARS-CoV Toll-like Receptor (TLR) Fungal HIV Flavivirus Infection Inflammation/Immunology
    Retrocyclin-101 (RC-101) is a synthetic cyclic θ-defensin, a broad-spectrum antimicrobial peptide with anti-pathogen (covering viruses, bacteria and fungi) activity and anti-inflammatory activity. Retrocyclin-101 exhibits significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus and others. Retrocyclin-101 inhibits TLR4 and TLR2-mediated signal transduction and reduces pro-inflammatory cytokine expression .
    Retrocyclin-101
  • HY-145324
    Antiviral agent 14

    		TMV Infection
    Antiviral agent 14 is an antiviral agent against the tobacco mosaic virus (TMV) and cucumber mosaic virus (CMV). The EC50 values of Antiviral agent 14 against TMV and CMV with EC50 values of 135.5 μg/mL and 178.6 μg/mL, respectively .
    Antiviral agent 14
  • HY-N7194
    Yadanzioside L

    		TMV Infection
    Yadanzioside L is a quassinoid and shows anti-tobacco mosaic virus (TMV) activity (IC50=4.86 μM) .
    Yadanzioside L
  • HY-155044
    TMV-IN-5

    		TMV Fungal Infection
    TMV-IN-5 (compound 1a) is an anti-plant virus/fungal agent. TMV-IN-5 inhibits viral assembly by binding to tobacco mosaic virus (TMV) CP. TMV-IN-5 can be used in the development of pesticides .
    TMV-IN-5
  • HY-148569
    TMV-IN-3

    		TMV Bacterial Infection Inflammation/Immunology Cancer
    TMV-IN-3, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-3 has antiviral activity against TMV with an EC50 value of 120.3 μg/mL. TMV-IN-3 can be used for the research of infection, inflammation and tumor .
    TMV-IN-3
  • HY-N8521
    6-O-Methacrylate

    		TMV Parasite Infection
    6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity .
    6-O-Methacrylate
  • HY-148567
    TMV-IN-1

    		TMV Bacterial Infection Inflammation/Immunology Cancer
    TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor .
    TMV-IN-1
  • HY-N10110
    (±)-Phrymarolin II

    		TMV Infection
    (±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.
    (±)-Phrymarolin II
  • HY-163201
    TMV-IN-7

    		TMV Infection
    TMV-IN-7 (compound G2) is a potent inhibitor of tobacco mosaic virus (TMV). TMV-IN-7 exhibits strong hydrophobic interactions to obstructing the virus’s self-assembly .
    TMV-IN-7
  • HY-N15076
    Herbimycin B

    		Src Antibiotic Bacterial Infection Cancer
    Herbimycin B is an ansamycin antibiotic that acts as a Src family kinase inhibitor. Herbimycin B has herbicidal effect on most monocotyledons and dicotyledons, inhibits the activity of tobacco Mosaic virus (TMV), HeLa cells and Ehrlich cells .
    Herbimycin B
  • HY-155045
    TMV-IN-6

    		TMV Infection
    TMV-IN-6 (Compound 4g) is a novel antiviral and fungicidal agent. TMV-IN-6 inhibits virus assembly by binding totobacco mosaic virus (TMV) CP and interfere with the assembly process of TMV CP and RNA .
    TMV-IN-6
  • HY-Y0507R
    DL-Serine (Standard)

    		Reference Standards TMV Infection Cancer
    DL-Serine (Standard) is the analytical standard of DL-Serine. This product is intended for research and analytical applications. DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV)[1].
    DL-Serine (Standard)
  • HY-W718796
    DL-Serine-15N

    		Isotope-Labeled Compounds TMV Cancer
    DL-Serine- 15N is 15N-labeled DL-Serine (HY-Y0507) DL-Serine, a fundamental metabolite, is a mixture of D-Serine and L-Serine. DL-Serine has antiviral activity against the multiplication of tobacco mosaic virus (TMV).
    DL-Serine-15N
  • HY-152259
    TMV-IN-4

    		DNA/RNA Synthesis TMV Infection
    TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco .
    TMV-IN-4
  • HY-160641
    isoG Nucleoside-1

    		Others Others
    isoG Nucleoside-1 (compound 15) is an isoguanine (isoG) nucleoside. In the HNA(h)-DNA(d) mosaic scaffold, h-isoG base mismatches follow the order G>C>T, while h-isoG base mismatches follow the order G>C>T .
    isoG Nucleoside-1
  • HY-162400
    TMV-IN-8

    		TMV Infection
    TMV-IN-8 (compound 7 d) is an anti tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL.TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppressed TMV coat protein gene expression and biosynthesis process .
    TMV-IN-8
  • HY-163999
    TMV-IN-12

    		TMV Infection
    TMV-IN-12 (compound 4) is an inhibitor of tobacco mosaic virus (TMV) with antifungal properties. TMV-IN-12 effectively prevents TMV particle aggregation and self-assembly of TMV capsid protein (TMV-CP) (Kd=0.142 μM), preventing TMV from infecting tobacco plants .
    TMV-IN-12
  • HY-162807
    TMV-IN-10

    		TMV Infection
    TMV-IN-10 (compound 4h) is an arecoline derivative with anti-tobacco mosaic virus (TMV) activity (EC50=146 µg/mL). TMV-IN-10 can be used in research on controlling crop pests and diseases and improving crop yields by acting on the viral coat protein (CP) to cause viral fragmentation .
    TMV-IN-10
  • HY-159080
    HgCht2-IN-1

    		Parasite Infection
    HgCht2-IN-1 (compound 1516b) is a HgCht2 inhibitor that successfully inhibits the antagonism of cyst nematodes against nitrogen-fixing rhizobia and phosphate-absorbing arbuscular mycorrhizal symbionts. HgCht2-IN-1 can be used in the study of cyst nematode antagonism against microbial symbionts .
    HgCht2-IN-1
  • HY-163754
    TMV-IN-9

    		TMV Infection
    TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus (TMV) with an EC50 of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host .
    TMV-IN-9
  • HY-N1836
    3-Acetonyl-3-hydroxyoxindole

    3-Hydroxy-3-acetonyloxindole

    		 TMV Infection
    3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity .
    3-Acetonyl-3-hydroxyoxindole
  • HY-41404R
    Piperonylic acid (Standard)

    2H-1,3-benzodioxole-5-carboxylic acid (Standard)

    		 Cytochrome P450 Interleukin Related EGFR IGF-1R Reference Standards Infection Others Cancer
    Piperonylic acid (Standard) is the analytical standard of Piperonylic acid. This product is intended for research and analytical applications. Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities .
    Piperonylic acid (Standard)
  • HY-N18141
    Meliatoosenin N

    		TMV Infection
    Meliatoosenin N is a limonoid compound. Meliatoosenin N inhibits the replication of tobacco mosaic virus in vitro .
    Meliatoosenin N
  • HY-N17527
    7-Demethoxytylophorine N-oxide

    		Others Infection
    7-Demethoxytylophorine N-oxide is an alkaloid inhibitor of Tobacco Mosaic Virus. 7-Demethoxytylophorine N-oxide can be isolated from the aerial parts of Cynanchum komarovii. 7-Demethoxytylophorine N-oxide is applicable to research related to Tobacco Mosaic Virus infection .
    7-Demethoxytylophorine N-oxide
  • HY-N18115A
    Toosendansin A

    		Drug Derivative Cancer
    Toosendansin A is a salannin-type limonoid and cytotoxic agent found in the fruits of Melia azedarach. Toosendansin A can be used for the research of leukemia, stomach cancer, breast cancer .
    Toosendansin A
  • HY-113053F
    Prostaglandin A1-biotin

    PGA1-biotin

    		 Drug Derivative Infection
    Prostaglandin A1-biotin (PGA1-biotin) is a biotin-labeled Prostaglandin A1 (HY-113053). Prostaglandin A1-biotin can be found in the culture filtrate of rhizobia, and the culture filtrate containing this compound exhibits significant antiviral activity .
    Prostaglandin A1-biotin
  • HY-P5642A
    Retrocyclin-101 TFA

    RC-101 TFA

    		 HIV SARS-CoV Influenza Virus Flavivirus HSV Bacterial Fungal Toll-like Receptor (TLR) Ser/Thr Protease Infection Inflammation/Immunology
    Retrocyclin-101 (RC-101) TFA is an artificially synthesized, cyclic-structured θ-defensin, a broad-spectrum agent with antimicrobial (covering viruses, bacteria, and fungi) activity and anti-inflammatory activity. Retrocyclin-101 TFA can inhibit the serine protease activity of ZIKV NS2B-NS3, with an IC50 of 7.20 μM. Retrocyclin-101 TFA has significant inhibitory activity against HIV, SARS-CoV-2, flaviviruses, influenza viruses, HSV-1/2, Staphylococcus aureus, etc. Retrocyclin-101 TFA inhibits the signal transduction mediated by TLR4 and TLR2, reducing the expression of pro-inflammatory cytokines .
    Retrocyclin-101 TFA

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