94-53-1
94-53-1
Chemical Structure
Piperonylic acid
Synonym(s): 2H-1,3-benzodioxole-5-carboxylic acid
- CAS No.: 94-53-1
- Formula:C8H6O4
- Molecular Weight:166.13
IUPAC Name: benzo[d][1,3]dioxole-5-carboxylic acid
InChIKey: VDVJGIYXDVPQLP-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(OCO2)C2=C1)O
Biological Activity: Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities[1][2][3][4].
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Piperonylic acid | 99.91% | Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities. | ||||||||||||||||||||
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Piperonylic acid (Standard) | ≥98% | Piperonylic acid (Standard) is the analytical standard of Piperonylic acid. This product is intended for research and analytical applications. Piperonylic acid is a natural molecule bearing a methylenedioxy function that closely mimics the structure of trans-cinnamic acid. Piperonylic Acid is a selective, mechanism-based inactivator of the trans-cinnamate 4-Hydroxylase. Piperonylic acid has anticancer, antioxidant and antibacterial activities. | ||||||||||||||||||||
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References
- [1]. Schalk M, et al, Werck-Reichhart D. Piperonylic acid, a selective, mechanism-based inactivator of the trans-cinnamate 4-hydroxylase: A new tool to control the flux of metabolites in the phenylpropanoid pathway. Plant Physiol. 1998;118(1):209‐218. [Content Brief]
- [2]. Lee D, et al. Piperonylic acid stimulates keratinocyte growth and survival by activating epidermal growth factor receptor (EGFR). Sci Rep. 2018 Jan 9;8(1):162. [Content Brief]
- [3]. Zarai, Zied, et al. "Antioxidant and antimicrobial activities of various solvent extracts, piperine and piperic acid from Piper nigrum." Lwt-Food science and technology 50.2 (2013): 634-641.
- [4]. Moreira KG, et al. Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition. PLoS One. 2021 Oct 26;16(10):e0259134. [Content Brief]
