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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
mutant Cu
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "mutant Cu" in MCE Product Catalog:
Cat. No.: HY-165381
CAS No.: 71555-14-1
Research Areas:
ZMC2 is a thiosemicarbazone-class metal ion chelator and zinc ionophore with a human mutant p53 R175H binding Ka of 27.4 nM.ZMC2 binds Fe, Cu, Mn, Zn, and other transition metals.ZMC2 facilitates zinc transport across membranes.ZMC2 restores zinc binding to zinc-deficient p53 mutants, restoring wild-type structure and function, including site-specific DNA binding.ZMC2 generates reactive oxygen species (ROS).ZMC2 can be used for the research of cancer .
Cat. No.: HY-187665
CAS No.: 489402-79-1
Target:
Research Areas:
SOD1-Derlin-1-IN-3 is a mutant SOD1 (SOD1mut) inhibitor. SOD1-Derlin-1-IN-3 blocks the interaction between SOD1mut and Derlin-1 by preferentially binding to the Derlin-1 binding region (DBR) of SOD1mut, without affecting SOD enzyme activity. SOD1-Derlin-1-IN-3 can be used for research on amyotrophic lateral sclerosis (ALS) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
